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Zoology- Bio 1B
Circulation
26
Biology
Undergraduate 1
10/12/2006

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Term
Circulatory System Components
Definition
1. Circulatory Fluids
2. Vessels
3. Pump
4. Valves
Term
Circulatory System Roles
Definition
Transport to and from cells:
1. CO2 and O2
2. Nutrients and metabolites
Term
Types of Circulatory Systems
Definition
1. Ciliated
2. Open
3. Closed
Term
Ciliated Systems
Definition
-Use cilitated body cavity for circulation
-Gastrovascular System: Cnidarians and Platyhelminths(ciliated with branching extensions)
-Water Vascular System: Echinoderms(ciliated with extensions for respiration)
Term
Open Systems
Definition
-Have dorsal vessel pumping blood mixed with lymph
-Hemolymph exits doral vessel into body cavity and returns via ostia or veins
-Arthropoids and molluscs
-Drawbacks are backwaters and eddies cause poor oxygenation and poor diffusion gradients
Term
Closed Systems
Definition
-Connect arteries and veins by adding capillaries
-Better circulation means higher activity levels
-Earthworms
Term
Invertebrate Closed Systems
Definition
-Cephalopods have three hearts; one for each gill and one for the body
-Annelids have even more hearts
-Invertebrates' heart is from dorsal vessel
Term
Vertebrate Hearts
Definition
-Heart is from ventral, not dorsal vessel
-Vein to Atrium to Vetricle to Artery
-No pumping mechanism after capillaries to raise pressure
Term
Two Chambered Heart
Definition
-Fishes
-Systemic blood isn't pressurized
-If the heart is working harder, it will receive blood that has less O2
-Fill capillaries and sysemtic capillaries, artery, vein and heart
Term
Three Chambered Heart
Definition
-In Amphibians and some reptiles(snakes and lizards) -Two atria and one ventricle where blood gets mixed -Greater systemic pressure for hihger activity levels heart gets fresher blood -lung and skin capillaries and systemic capillaries [image]
Term
four chambered heart
Definition
-Crocodilians, birds and mammals -Pulmonary circuit; no mixing of oxyenated and deoxygenated blood -Fully oxygenatged blood to organs and fully deoxygenated blood to lungs -Lung capillaries and systemic capillaries [image]
Term
Capillaries
Definition
-Everywhere in Body
-Only <1% open at any one time; 2000mm^2
-Surface area is 1000 square miles
-Most sphincters are relaxed
-Leaky because one-celled thick
-Allows diffucsion of nutrients and gases
-Hydrostatis pressure forces blood out
-oxmotic pressure recaptures much of it
-The rest is caught by the lymph system
Term
Lymph System
Definition
-Lost fluids are recaptured by extensive open-ended lymph ducts
-skeletal muscles pump those recaptured fluids to the heart
-Defends against antigens/germs
Term
First Line of Defense
Definition
-Skin and cilitate mucous membranes
Term
Second Line of Defense
Definition
-Inflammation, Clotting and Phagocytosis
-Raptured mast cells at injury site release histamines, which attract WBCs(phagocytes and macrophages) and also dilate capillaries which makes them leakier
-
Term
What are the steps in the Clotting Process?
Definition
1. Plateletes
2. Clotting Factors
3. Prothrombin
4. Thrombin
5. Fibrinoen
6. Fibrin: fibrous protein; forms clot
-Leukemia victims lack plateletes and Hemophiliacs lack clotting factors
Term
White Blood Cells(WBC)
Definition
-Inside the lymph nodes, which is why the doctor feels the throat
-Eosinophils, neutrophils, macrophages,etc.
-Each type specializes on a class of invader
-Macrophages and dendritic cells are main phagocytes
Term
Acquired Immunity
Definition
-Slower respones to specific microbes
-B-cells: made by bone marrow; also from spleen; against extracellular pathosgen like bacteria
-T-cells: made by thymus; against intracellular pathogens like viruses
Term
Innate Immunity
Definition
-Fast response to a broad range of microbes
1.External Defenses: mucous and skin
2.Internal Defenses: Inflammation, natural killer cells, Phagocytic cells, and antimicrobial proteins
Term
B-Cells
Definition
-Variable; Some have antibodies that match antigens(from pathogens)
-Antibodies are surface protein of B-cells; tag pathogen for destruction
-Antigen: Antibody generators
-A b-cell whose binding site matches an antigen is said to be "selected"; it clones into many cells and two cell types result: Attacking plasma cells or Long-lived memory cells(idle plasma cell factories)
Term
Antibodies
Definition
-Causes neutralization, agglutination(clustering of antigens, precipitation(make solid) or simply rupturing
Term
Secondary Immune Response
Definition
-Get a disease you get natural immunization -Immunization: injecting chemical or heat inactivated antigens [image]
Term
Jenner
Definition
-Put Vaca in Vaccination
-Cow pox helped protect from small pox
-1796
Term
Pathogen Evolution
Definition
-Evolve to avoid detection; Most pathogens change surface proteins so memory cells don't recognize them
-pathogesn have shorter generation time and evolve faster than their larger hosts
-AIDS: intracellular invaders and T-cells
Term
T-Cells
Definition
-Like B-cells; have diverse antigen receptor sites and come in two different functional types
-Helper T Cell: Help B-cells
-Cytotoxic T Cell: MHCs label diseased or cancerous for attack by these
Term
Major Histocompatibility Complex(MHCs)Genes
Definition
-Have ~100 alleles
-Each MHC molecules type presents a different type of antigen for T cells to recognize as alien
-Gene polymorphism increases chances of matching antigens, so higher MHC diveristy the higher the disease resistance
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