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z- Glycolysis
BCH 4054 Perez, Manuel Spring 2011
14
Chemistry
01/22/2011
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Term
Regulation Step
 Definition
PFK (Phosphofructo Kinase)
Term
Glucose to G6P
 Definition
Hexokinase + Mg2+ + ATP

G6P
Term
G6P to F6P
 Definition
PGI (phosphoglucose isomerase)
Term
F6P to FBP
 Definition
PFK (Phosphofructo Kinase) + Mg2+ + ATP
ONE WAY (regulation step)
Term
FBP to DHAP + GAP
 Definition
Aldolase
Term
DHAP to GAP
 Definition
TIM (Triose Phosphate Isomerase)
Term
GAP to 1,3 BPG
 Definition
GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) + NAD+ + Pi

Note: reaction happens twice per original glucose
Term
1,3-BPG to 3PG
 Definition
PGK (Phosphoglycerate Kinase) + ADP + Mg2+

Note: reaction happens twice per original glucose
Term
3PG to 2PG
 Definition
PGM (Phosphoglycerate Mutase)
Term
2PG to PEP
 Definition
Enolase + Mg2+

Note: reaction gives off H2O
reaction happens twice per original glucose
Term
PEP to Pyruvate
 Definition
PK (Pyruvate Kinase) + ADP + Mg2+ + K+

Note: reaction happens twice per original glucose
Term
Where does Galactose enter
 Definition
G6P
Term
Where does Mannose enter
 Definition
F6P
Term
Where does Fructose enter
 Definition
F6P (Muscle)
GAP (Liver)