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Z 331 Second Midterm
Anatomy and Physiology Chapters 6-9
129
Anatomy
Undergraduate 3
07/06/2009

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Term
What makes up the Skeletal System?
Definition
Bones, cartilages, ligaments, and other connective tissues that stablize or connect the bones
Term
What are the 5 primary functions of the Skeletal System
Definition
Support, Storage of Minerals and Lipids, Blood Cell Production, Protection, and Leverage

SSBPL
Super Strong Bones Protect Life
Term
Bone is also known as?
Definition
Osseous Tissue
Term
What are the 6 Broad Categories of Bones?
Definition
Long, Flat, Sutural, Irregular, Short, Sesamoid
LFSISS
"Look For Stuff In Small Spaces"
Term
What is another name for Sutural bones?
Where are Sutural bones located
Definition
Wormian bones
between the flat bones of the skull
Term
What Sesamoid bone does everyone have?
Definition
patellae
Term
Process - related to the bone surface
Definition
Any projection or bump
Term
Ramus - related to the bone surface
Definition
An extension of a bone making an angle with the rest of the structure
Term
Trochanter - related to the bone surface
Definition
A large, rough projection
Term
Tuberosity - related to the bone surface
Definition
A smaller, rough projection
Term
Tubercle - related to the bone surface
Definition
A small, rounded projection
Term
Crest - related to the bone surface
Definition
A Prominent Ridge
Term
Line - related to the bone surface
Definition
A low ridge
Term
Spine - related to the bone surface
Definition
A pointed process
Term
Head - related to the bone surface
Definition
The expanded articular end of an epiphysis, separated from the shaft by a neck
Term
Neck - related to the bone surface
Definition
A narrow connection between the epiphysis and the diaphysis
Term
Condyle - related to the bone surface
Definition
A smooth, rounded articular process
Term
Trochlea - related to the bone surface
Definition
A smooth, grooved articular process shaped like a pulley
Term
Facet - related to the bone surface
Definition
a small, flat articular surface
Term
Fossa - related to the bone surface
Definition
A shallow depression
Term
Sulcus - related to the bone surface
Definition
A narrow grove
Term
Foramen - related to the bone surface
Definition
A rounded passageway fro blood vessels or nerves
Term
Canal - related to the bone surface
Definition
A passageway through the substance of a bone
Term
Fissure - related to the bone surface
Definition
An elongate cleft
Term
Sinus or antrum - related to the bone surface
Definition
A chamber within a bone, normally filled with air
Term
define diaphysis
Definition
extended tubular shaft
Term
What is the expanded area at each end of the diaphysis called?
Definition
epiphysis
Term
define metaphysis
Definition
the area where the diaphysis and the epiphysis connect to each other
Term
What kind of bone primarily makes up the diaphysis?
Definition
Dense bone
Term
What kind of bone mostly makes up the epiphyses
Definition
spongy bone
Term
In Flat bone What is the layer of spongy bone between the layers of compact bone referred as?
Definition
Diploe
Term
what are osteocytes?
Definition
bone cells
Term
What is the outer surface of bone covered with
Definition
Periosteum
Term
What accounts for almost 2/3 of the wight of bone
Definition
Calcium phosphate
Term
Define Osteoblast
Definition
Immature bone cell that secretes organic components of matrix
Term
Define Osteoclast
Definition
Multinucleate cell that secretes acids and enzmes to dissolve bone matrix
Term
The basic functional unit of mature compact bone is?
Definition
the Osteon
Term
define - endosteum
Definition
incomplete cellular layer that lines the marrow cavity
Term
What are the pockets called that contain bone cells?
Definition
lacunae
Term
Narrow passageways through the bone matrix used to exchange nutrients, waste products and gases
Definition
Canaliculi
Term
define hydroxyapatite
Definition
crystals formed from calcium phosphate and calcium hydroxide
Term
What is the process called when osteoblasts produce new bone matrix
Definition
osteogenesis
Term
What is the function of osteoprogenitor cells?
Definition
maintain populations of osteoblasts
Term
The process by which osteoclasts dissolve bone matrix?
Definition
osteolysis
Term
Central Canal runs in which direction
Definition
parallel to the surface
Term
perforating canals run which direction?
Definition
perpendicular to the surface
Term
What are trabeculae
Definition
the struts and plates in spongy bone forms
Term
T or F There are no capillaries in the matrix of the spongy bone
Definition
True: nutrients move via diffusion
Term
[image]
Definition
[image]
Term
define ossification
Definition
process of replacing other tissues with bone
Term
Most bones originate as what?
Definition
Hyaline cartilages
Term
the process that converts cartilage into bone is called
Definition
endochondral ossification
Term
the process when bone developes directly from mesenchyme or fibrous connective tissue
Definition
intramembranous ossification
Term
When dermal bones form in abnormal locations
Definition
heterotopic bones
Term
What are the three major sets of blood vessels found in typical bone
Definition
The Nutrient Artery and Vein, Metaphyseal Vessels, Periosteal Vessels
Term
Produced by the kidneys, Promotes calcium and phosphate ion abosorption along the digestive tract
Definition
Calcitriol
Term
Produced in the pituitary gland, it stimulates osteoblast activity and the synthesis of bone matrix
Definition
Growth Hormone
Term
Produced in the thyroid gland, alont with growth hormone it stimulates osteoblast activity and the synthesis of bone matrix
Definition
Thyroxine
Term
What is the effect of Calcitonin on the skeletal system
Definition
Inhibits osteoclast activity, promotes calcium loss at kidneys, reduces calcium ion concentrations in body fluids ↓ blood Ca++ levels (↑ bone deposition)
Term
Which hormones are involved in calcium ion homeostasis
Definition
parathyroid and calcitonin
Term
What are the three major effects of parathyroid hormone
Definition
stimulates osteoclast activity, increases the rate of intestinal absorption of calcium ions, decreases the rate of excretion of calcium ions at the kidneys ↑ blood Ca++ levels (↑ bone resorption)
Term
What are the major function of calcitonin
Definition
inhibits osteclast activity, increases the rate of excretion of calcium ions at the kidneys
Term
define osteopenia
Definition
inadequate ossification, bone become thinner and weaker
Term
define osteoporosis
Definition
when the reduction in bone mass is sufficient to compromise normal function
Term
define canaliculi
Definition
interconnect adjacent osteocytes
Term
The more inorganic material that s present in the bone_______
Definition
The harder and more rigid the bone becomes
Term
Organic material in the bone give bone it's?
Definition
flexibility and tensile strength.
Term
Steps of Intramembranous Ossification
Definition
Osteoblasts develop
in dermal layer - Osteoblasts cluster
and secrete osteoid
(ossification center)- Osteoblasts trapped;
convert to osteocytes - Trabecula form - Bone collar forms
(compact bone);
Periosteum forms
Term
Define appositional Growth
Definition
when a bone increases in diameter
Term
Steps of Endochondral Ossification
Definition
Hyaline cartilage
forms - Osteoblasts form
in periosteum;
build bone collar
(diaphysis)- Diaphysis center
calcifies; cavity forms
(primary ossification center -Blood vessels
invade cavity;
spongy bone forms - Diaphysis elongates;
epiphyses ossify
(secondary ossification centers
Term
What is the Epiphyseal Plate:
Definition
Line of cartilage
separating epiphysis
from diaphysis
Term
Interstitial Growth
Definition
Increases bone length
• Growth occurs at epiphyseal plates
Term
Fibrodysplasia Ossificans Progressiva
Definition
(Uncontrolled bone growth)
Bone formed from muscle:
Myoblasts → Osteoblasts
Term
What percent of bone mass is recycled each week
Definition
5 - 7% of bone mass
Term
Wolff’s Law:
Definition
Bones remodel in response to forces placed
on them
Term
Steps in a bone repair of a fracture
Definition
Step 1: Hematoma Formation:
Step 2: Cartilaginous Callus Formation:
• Clotting seals injured blood vessels
• Cartilage fills in damaged area
Step 3: Bony Callus Formation:
Step 4: Bone Remodeling:
• Spongy bone replaces cartilage
• Compact bone replaces spongy bone
Term
What are the influencing factors of osteoporosis
Definition
Influencing Factors:
1) ↓ sex hormones
2) Calcium deficiency
3) Vitamin D deficiency
4) Inactivity
Term
Trichinosis
Definition
infection by the parasitic nematode (larval worms),
muscle pain, diarrhea, and weakness.
Term
Fibromyalgia
Definition
diagnosis=key
pattern of tender points in 11 of 18 known locations.
– Pain cannot be explained by any other mechanisms.
Term
Muscular Dystrophies
Definition
an inherant disease caused by
a mutation in one of many genes that effect muscle
function. Ca++ channels in the sarcoplasm raise to a
point that proteins denature. Rx=Steroid treatment
decrease inflammation slows the progression of the
disease
– The mutations commonly display characteristics between the
ages of 3 and 7. Effects primarily skeletal muscle but in latter
stages facial muscles and cardiac muscles are involved. Most
individuals die before age 20.
Term
kyphosis
Definition
thoracic curvature
Term
lordosis
Definition
swayback, abdomen and buttocks an xageration of the lumbar vertebra
Term
scoliosis
Definition
lateral curvature of the spine
Term
Spin Bifida
Definition
during the third week of develpoment, the vertebral arches form around the spinal chord develops abnormally, the arch is incomplete and the spinal cord bulge out, cause is from low levels of folic acid.
Term
Acromegaly
Definition
high levels of HGH released after puberty, abnormal growth of hands, feet, lower jaw, skull, etc,
Term
Osteogenesis imperfecta
Definition
brittle bones, loose ligaments and tendons
Term
Marafin’s Syndrome
Definition
extremely long slender limbs, abnormal epiphyseal activity
Term
Achondroplasia
Definition
slow epiphyseal growth, trunk is normal size and limbs are much shorter.
Term
Joint (articulation)
Definition
Site where two or more bones meet
Term
Types of Joints?
Definition
Synarthroses (immovable joints), Amphiarthroses (slightly movable joints),Diarthroses (freely movable joints)
Term
Examples of Synarthroses joints?
Definition
a) Suture (e.g. skull)
• Bones interlocked (fibrous)
b) Gomphosis (e.g. teeth)
• Peg-in-socket connection (fibrous)
c) Synchondrosis (e.g. epiphyseal plates)
• Plate connects bones (cartilaginous
Term
Examples of Amphiarthroses Joints?
Definition
2) Amphiarthroses (slightly movable joints)
• Cord/sheet connect bones (fibrous)
• Broad disk connects bones
a) Syndesmosis (e.g. tibia/fibula)
b) Symphysis (e.g. vertebrae
Term
Diarthroses is also known as
Definition
Synovial Joints (e.g. end of long bones)
permits the wides range of motion
Term
From the superior to the inferior of a Synovial Joint in what order is the joint built
Definition
Periosteum - synovial membrane - Articular cartilage - joint cavity (contians synovial fluid) articular capsule
Term
what is the meniscus
Definition
a pad of fibrocartilage situated between opposing bones wihthin synovial jiont
Term
Gliding Joint
Definition
nonaxia, carpal bones
Term
Hinge Joint
Definition
Uniaxial, e.g. elbow
Term
Pivot Joint
Definition
Uniaxial, radioulnar joint
Term
Ellipsoidal Joint
Definition
Biaxial, e.g. knuckle
Term
Saddle Joint
Definition
Biaxial, e.g. Thumb
Term
Ball-and-Socket Joint
Definition
Multiaxial, e.g. shoulder
Term
Sprain
Definition
Ligaments stretched / torn
Term
Dislocation
Definition
Bones forced out of normal position
Term
Cartilage Damage
Definition
Tearing of cartilage (e.g. meniscus)
Term
Bursitis
Definition
Irritation of fluid-filled pockets (friction / shock absorption
Term
Tendonitis:
Definition
Inflammation of tendon sheaths (overuse
Term
Arthritis:
Definition
Articular cartilage destruction (pain, swelling, stiffness
Term
Rheumatoid arthritis
Definition
autoimmune disease
Term
Define Bursae
Definition
small, fluid-filled pockets in connective tissue
Term
Function of a tendon
Definition
limit the joint's range of motion and provide mechanical support for it
Term
Function of ligaments
Definition
support, strenghtn and reinforce synovial joints
Term
Types of Movement - Gliding
Definition
two surfaces slide past one another
Term
Types of Movement - Flexion
Definition
reduces the angle
Term
Types of Movement - Extension
Definition
increases the angle
Term
Types of Movement - hyperextension
Definition
extension past the anatomical position
Term
Types of Movement - Abduction
Definition
moving away from the longitudinal axis
Term
Types of Movement- adduction
Definition
back to anatomical position
Term
Types of Movement - Circumduction
Definition
moving in a loop
Term
What is the purpose of articular cartilage?
Definition
prevents bony surfaces at a synovial joint from contacting one another
Term
3 important components to levers
Definition
Load (resistance)
Fulcrum
Effort (applied force
Term
What is a Mechanical advantage
Definition
Small effort over a large distance
Load is closer to fulcrum
Less effort moves a large load a small distance
Term
Mechanical disadvantage
Definition
Effort is larger than load
Effort closer to fulcrum
Effort allows load to move rapidly over a large
distance
Term
Example of a First Class Lever
Definition
Fulcrum located between load and force
very few in the human body
Term
Example of a Second class lever
Definition
Load found between effort and fulcrum
• Small force can move a large weight
Term
example of a Third class lever
Definition
Force applied between load and fulcrum
Load is moved quickly and farther at
expense of effort
• Always at a mechanical disadvantage
Most common lever in human body
Term
Inversion
Definition
twisting motion of the foot that turns the sole inward.... oppostite is eversion
Term
Dorsiflexion
Definition
elevation of the sole when you dig in your heel opposite is plantar flexion
Term
Opposition
Definition
Thumb to the surface of the palm.
Term
Protraction
Definition
jaw moving moving forward....opposit is retraction
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