Term
| what is the transformation zone of the cervix? |
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Definition
-where the squamous cells of the outside of the cervix meet the columnar cells of the canal of the cervix
-where abnormal growth and dysplasia most often develops |
|
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Term
| What is CIN? what is the major cause? |
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Definition
cervical intraepithelial neoplasia- the abnormal growth of potentially precancerous cells in the cervix
-major cause is infxn with HPV types 16 or 18 |
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Term
| ACOG guidelines december 2009 state that Paps should be started when? |
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Definition
| at the age of 21, regardless of the age of first sexual intercourse |
|
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Term
| women aged 21-29 should get Paps how often? |
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Definition
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Term
| women over 30 yoa who have had 3 consecutive negative tests can be screen every ___ years |
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Definition
|
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Term
| when is it reasonable to discontinue pap screening? |
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Definition
| at either 65 or 70 years of age if they have had three or more negative tests in a row in the past 10 years |
|
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Term
| pap recommendations for women who have had a benign hysterectomy? |
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Definition
|
|
Term
| women with a hx of high grade lesions prior to their hysterectomy, pap recs? |
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Definition
| pap screened every year for 20 years |
|
|
Term
| pap recs for women with hx of cervical CA or severe dysplasia? |
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Definition
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Term
| what happens if endocervical cells are absent on the pap results? post menopausal women? pregnant women? all other? |
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Definition
-post men: if all paps have been normal to this point, can have repeat in 1 year
-pregnant: should be rescreened after baby is born
-others; should be rescreened in 6 months time |
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Term
| which is a more serious pap result? ASC-US or AGC-US? |
|
Definition
|
|
Term
|
Definition
findings of CIN1
findings consistent with HPV infection |
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|
Term
|
Definition
|
|
Term
| cervical ca stage 0 means? |
|
Definition
| full thickness involvement of the epithelium w/o invasion into the stroma (Carcinoma in situ) |
|
|
Term
|
Definition
| limited to cervix, no spread to nodes |
|
|
Term
|
Definition
|
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Term
|
Definition
| the cancer has spread to the lower part of the vagina or the walls of the pevlis. cancer may be blocking the uretrs, its has not spread to nearby lymph nodes or to distant sites |
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Term
|
Definition
A- invades mucous of bladder or rectum and/or extends beyond the true pelvis, no nearby nodes are involved, no distant organs are involved,
B- distant metastasis, such as lungs or liver |
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Term
| 35% of pts with invasive cervical CA have ______ disease after treatment |
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Definition
|
|
Term
| what are 3 options for treatment of ASC-US paps? |
|
Definition
-repeat pap until 2 consecutive normal paps
OR
-immediate colposcopy
OR
-DNA testing for high risk types of HPV |
|
|
Term
| tx of women with ASC-US pap and + HPV? - HPV? |
|
Definition
-colposcopic eval
-follow up pap in 1 year |
|
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Term
|
Definition
| colposcopy with endocervical sampling |
|
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Term
|
Definition
| follow up paps at 4-6 month intervals is indicated until there are 4 consecutive negative paps. |
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Term
|
Definition
| if initial work up is negative, these pts are treated in the same manner as those with adenocarcinoma in situ pap and require a diagnostic excisional procedure (cold knife cone biopsy) |
|
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Term
|
Definition
| should be referred for colposcopy and endocervical sampling is preferred |
|
|
Term
|
Definition
| colposcopy with endocervical sampling. |
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