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Week One Biochem Review II
Water powerpoint
29
Chemistry
Professional
09/19/2009

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Term
Bond strength depends on four things:
Definition
temperature, pressure, bond angle, & environment
Term
Water has ________ bonds among _________ on one water molecule & the __________ on another water molecule
Definition
hydrogen; hydrogens; oxygen
Term
each water molecule can bind up to _______ other water molecules, through partial charges of hydrogen bonding
Definition
4
Term
Water has a __________ bond between the ______ atom & the _________ atom
Definition
covalent; oxygen and hydrogen
Term
small localized __________ charge around the oxygen atom & a small localized _________ charge around the hydrogen atoms
Definition
negative; positive
Term
This uneven distribution of positive and negative charges classifies water as a_______ _________ __________.
Definition
polar covalent bond
Term
Water is a _____________.
Definition
nucleophile
Term
Water Donates unpaired e- to ______________.
Definition
electrophiles
Term
Water can act as both what?
Definition
acid and base
Term
H+ typically are responsible for increasing/decreasing pH
Definition
decreasing
Term
OH- typically are responsible for __________ pH.
Definition
raising
Term
water is often in a _____________ equilibrium
Definition
dissociation
Term
Intracellular fluid (ICF; fluid inside the cell)
- makes up ____% of body weight
- has a 11:1 ratio of __ to ___
Definition
40%; K to Na
Term
Extracellular fluid: (ECF; fluid outside the cells)
- makes up ___% of bodyweight.
- has a 14:1 ratio of __ to __
Definition
20%; Na to K
Term
Interstitial fluid (ISF) surrounds the cells but doesn’t _______ and makes up about ___ of the ECF
Definition
circulate; three fourths
Term
________ makes up about ¼ of the ECF & circulates
Definition
Plasma
Term
____ is the main cation in plasma
Definition
Na+
Term
___ is the main anion in plasma
Definition
Cl-
Term
main anions in ICF are __________.
Definition
proteins
Term
Osmosis: type of diffusion of water through any barrier from a solution of ___ solute concentration to a solution of ____ solute concentration
Definition
low; high
Term
An increase in ECF osmolality (ion concentration) leads to movement of water from the cells into the ECF, and ultimately to________ _________.
Definition
cellular dehydration
Term
When ECF osmolality (ion concentration) decreases water moves______ the cell from the ECF. ______ soon follows
Definition
into; edema
Term
ECF hypertonic –____ ion concen-relative to cell
Definition
high
Term
ECF hypotonic –____ ion conc-relative to cell
Definition
low
Term
Regulation of water balance depends on:
Definition
1) hypothalamic mechanisms controlling
thirst
2) ADH (anti-diuretic hormone)
3) retention or excretion of water by the
kidneys
4) evaporative losses due to respiration &
perspiration
Term
The ________ play a vital role in maintaining the composition & volume of the ______.
Definition
kidneys; ECF
Term
When circulating extracellular fluid decreases by ~10%, get thirsty & triggers __________ ______ __________.
Definition
non-osmotic ADH release
Term
hypovolemic (low volume) thirst – your body is ________ from _________.
Definition
dehydrated; sweating
Term
Nephrogenic Diabetes Insipidus
Definition
Results from inability of renal tubular ADH osmoreceptors (in kidneys) to respond to ADH
Cannot respond to subtle changes in ECF osmolarity
Characterized by extreme thirst, high water intake
& inability to concentrate urine; these symptoms are similar to those observed in Diabetes Mellitus
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