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Week 4
Chapter 21-Vaccines
27
Pharmacology
Undergraduate 3
11/24/2014

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Term
Nonspecific immunity
Definition
Initial defense, physical barriers such as intact skin, mucus production, inflammation, fever, & phagocytosis of foreign bodies are examples of what type of immunity?
Term
Specific immunity
Definition

Defense vs. specific antigen, B- and T-lymphocytes, and there are 4 ways to aquire this are examples of what type of immunity?

 

Term
Active immunity
Definition
This arrises when an animal receives an antigen that activates B- and T-Lymphocytes & causes animal to produce antibodies. Takes time to develop, but lasts a relatively long time due to memory.
Term
Passive Immunity
Definition
This arises when an animal receives antibodies from another anmal. Provides immediate protection, but for shorter periods of time.
Term
Natural Immunity
Definition
This type of immunity is aquired through during normal biological experiences.
Term
Artificial immunity
Definition
This type of immunity is aquired through medical procedures.
Term
Vaccines
Definition
These are a suspension of weakened, live, or killed microorganisms administered to prvent, improve, or treat infectious disease. They trigger a specific immune responce to help fight future infections from a speific agent.
Term
Inactivated (Killed) vaccine
Definition
This type of vaccine is made from microorganisms or their components that have bee hemically treated to kill the microorganism. Adjuvat needed to enhance immune response by increasing stability of the vaccine in the body.
Term
Attenuated (modified live) vaccines
Definition
This type of vaccine has microorganisms that have been altered to lose their virulence, but are still able to replicate with in the animal to provide immunity.
Term
Live vaccines
Definition
This type of vaccine is made from live microorganisms that may be fully virulent or avirulent.
Term
Recombinant vaccines
Definition
This type of vaccine is a gene or part of a microorganism removed from one organism (the pathogen) & inserted into another microorganism.
Term
Toxoids
Definition
This is a special type of vaccine used vs. toxins instead of microorganisms. Provides active immunity.
Term
Antitoxins
Definition
Substances that contain antibodies obtained from an animal that has beem hypersensitized to neutralize toxins. Used when exposure to toxin is likely. Provide passive immunity.
Term
Antiserum
Definition
Antibody rich serum from a hypersensitized or actually infected animal. ntibodies are colleced through plasma. Short lived (passive). Used against K9 distemper, Feline Panleukopenia, and bovine anthrax.
Term
Autogenous
Definition
Produced for a specific disease problem in a specific area from a sick animal. Cultured organisms from farm.
Term
Polyvalent vaccines
Definition
Mutiple-antigen vaccines contain more than one antigen.
Term

Sensitive to light, excessive heat, and freezing

Obtain from reputible source

Some vaccines need to be reconsttuted prior to use.

Use only diluent provided by manufacturer

Do not mix multiple vaccines in same syringe

Administer different vaccines in different sites.

Record where and how given.

Definition
Handling and care of vaccines:
Term
The refrigerator.
Definition
Where should vaccines be stored?
Term

Age

Health

Medications

Pregnancy

Environment

History

Definition
Name the patient considerations for vaccines.
Term
Local reaction at vaccine site
Definition
Pain & swelling are what type of vaccne reaction?
Term
Systemic reaction to vaccine
Definition
Anaphylaxis, hives, wheezing, dyspnea, hypotesion, and shock are what type of vaccine reaction?
Term
Sarcomas
Definition
Tumors of connective-tissue origin are what type of vaccine reaction?
Term
Antibody titers
Definition
These are used to assess the level of antibody to a particular antigen. Expressed in ratios such as 1:2, 1:4.
Term
Core vaccines
Definition
These vaccines are recomen ded for all individual animals because the consequences of infection are severe, infection poses zoonotic potiential, disease prevelence is high, Organism is eaily transmitted to other of its species. Vaccine is safe & effcacious.
Term
Rabies, DHPP, FRCP.
Definition
Examples of Core vaccines.
Term
Noncore vaccines
Definition
These vaccines are recommended only for individual animals deemed to be at high risk for contact with the organism. Based on evaluation of all risk factors.
Term
Bodatella
Definition
One example of a noncore vaccine.
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