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Week 11
sex linked and mitochondrial inheritence
26
Biology
Undergraduate 1
04/25/2012

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Term
when is gender determined?
Definition
during conception
Term
what two sets of organs are created during the 5th week of prenatal birth?
Definition
Unspecialized Gonads and Reproductive Ducts
Term
What is the difference between Mullerian and Wolffian reproductive ducts?
Definition
Wolffian: Male ducts,
Mullerian: Female Ducts
Term
is XX male?
Definition
no, XY is male
Term
what is the SRY gene and where is it found?
Definition
presence of the SRY gene determines if the baby will be a boy or not.
it is found on the Y chromosome
Term
what does HETEROGAMETIC mean and which gender does it describe?
Definition
it means that the genes are XY (hetero, different)
it is found in the germ line cells (testes) of males.
Term
what does HOMOGAMETIC mean and which gender does it describe?
Definition
it means that the genes are XX (homo, same)
it is found in the germ line cells (ovaries) of females
Term
which is bigger? the X or Y chromosome?
Definition
X, baby!!
Term
did you know that the X chromosome has more than 1500 genes?
and the Y chromosome has like 231 genes..
Definition
oh! interesting! :]
Term
what is the PAR? and is it on the X or Y chromosome?
Definition
PAR = pseudoautosomal regions
they make up only 5% of the genes and are located at the tips of the Y chromosome
Term
what is the MSY? and is it on the X or Y chromosome?
Definition
MSY = male specific region
makes up the large middle part of the Y chromosome. about 95%
Term
SRY and AZF are found on the Y chromosome.
what are they used for?
Definition
to make sperm
Term
which are functions of the SRY gene found on Y chromosomes?
a) found in the MSY of the Y chromosome
b) found in PAR of the Y chromosome
c) promote creation of male structures
d) demote creation of female structures
Definition
A and C
Term
Sex Influenced Traits:
Definition
traits that are influenced by Gender.... obviously.
so a heterozygous male will be bald.
but a heterozygous female will not just because she's female.
Term
X inactivation:
Definition
in females, because they have two X chromosomes, one will be deactivated.
the inactivated chromosome is called the BARR BODY
Term
what is the Barr Body? X or Y chromosome?
Definition
Barr body is the X chromosome in girls that is inactivated due to X-inactivation.
Term
what are XIST genes?
Definition
genes on inactive-X's that encodes an RNA that binds to it.
Term
DNA Methylation:
Definition
when Methyl groups bind to DNA and suppress gene expression
Term
True or False? imprints are erased and recreated after the gender is determined.
Definition
TRUE
Term
what is mtDNA? where is it found?
Definition
mtDNA is found inmitochondria
they have a high exposure to free radicals
they are more prone to mutation that regular DNA
Term
mitochondria interesting facts
Definition
-mitochondria have "mini-chromosomes"
-mitochondrial genes are passed down through the mother
Term
heteroplasmy deals with which organelle?
what is heteroplasmy?
Definition
mitochondria.
it is the idea that phenotype may change due to the amount of mutated mitochondria
Term
Epistasis
Definition
when one gene(1) cannot be expressed because the other gene(2) effected the trait gene (1) wanted to effect
Term
Plieotropy
Definition
when genes have ongoing, domino effecting, effects.
Term
Genetic HeteroGeniety
Definition
some phenotypes can be expressed with different genes
Term
phenocopy
Definition
traits that are effected by the environment, not genetics
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