Term
| What is the Composition of blood? |
|
Definition
| - Plasma, Plasma proteins and Blood Cells |
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Term
|
Definition
- Erythrocytes
- Leukocytes
- Thrombocytes |
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Term
| What is the function of Erythrocytes? |
|
Definition
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Term
| What is the function of Leukocytes? |
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Definition
| - Protect body from infection |
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Term
| What is the function of Platelets? |
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Definition
| - Promote blood coagulation |
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Term
| What are the Primary Lymphoid Organ? |
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Definition
|
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Term
| What are the Secondary Lymphoid Organs? |
|
Definition
- Spleen
- Lymph nodes
- Tonsils
- Peyer patches of small intestines |
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Term
| What is the purpose of the thymus? |
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Definition
| - Key in newborn immune response |
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Term
| What is the purpose of Bone Marrow? |
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Definition
| - Origin of hematopoeiesis |
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Term
| What is the purpose of the spleen? |
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Definition
| - Fetal hematpoeiesis (has phagocytes and lymphocytes -- immune) |
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Term
|
Definition
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Term
| What does hematpoiesis mean? |
|
Definition
|
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Term
| Where does Blood cell production originate? |
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Definition
|
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Term
| What are the two stages/divisions of of Blood cell production? |
|
Definition
- Mitotic Division (Replication)
- Maturation (Differentiation) |
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Term
|
Definition
| - Defend the body against organisms that cause infection and remove debris, including dead or injured host cells of all kinds |
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Term
| Where do Leukocytes primarily act? |
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Definition
| - in tissue, but are transported via circulation |
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Term
| What is the average number of Leukocytes in an adult? |
|
Definition
|
|
Term
| What are the 5 types of Leukocytes? |
|
Definition
- Neutrophil
- Lymphocytes
- Monocytes
- Eosinophils
- Basophils |
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|
Term
| Which Leukocytes have a Granulocyte structure? |
|
Definition
| - Neutrophils, eosinophils, basophils |
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Term
| Which Leukocytes have a Agranulocyte structure? |
|
Definition
|
|
Term
| Which Leukocytes have a Agranulocyte structure? |
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Definition
|
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Term
| Which Leukocytes are Phagocytes (Cells that ingest/digest bacteria)? |
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Definition
| - Neutrophils, Eosinophils, Basophils, Monocytes |
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Term
| Which Leukocytes are Immunocytes (Cells that create immunity)? |
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Definition
|
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Term
| What are the clinical evaluation of Hematologic System methods? |
|
Definition
- Bone marrow aspiration
- Bone marrow biopsy
- Blood test (CBC -- # of RBC, WBC, Platelets) |
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Term
| What is the condition called of an increase of WBC's? |
|
Definition
|
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Term
| What is the condition called of an decrease of WBC's? |
|
Definition
|
|
Term
| What is the condition called of an decrease of Neutrophils? |
|
Definition
|
|
Term
| What is the condition called of a marked decrease in Granulocytes? |
|
Definition
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Term
| What are the % of differentiating Leukocytes ex. Neutrophils..? Eosinophils...? Basophils...? Lymphocytes...? Monocytes...? |
|
Definition
- Neutrophils (50-67%)
- Eosinophils (0-3%)
- Basophils (0-2%)
- Lymphocytes (24-40%)
- Monocytes (4-9%) |
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|
Term
| What are mature Neutrophils called? |
|
Definition
|
|
Term
| What are immature Neutrophils called? |
|
Definition
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Term
| What does a shift to the left mean?...What does it signal? |
|
Definition
- Means that many band cells are in peripheral blood
- Signals acute stage infection |
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Term
| What does a shift to the left mean?...What does it signal? |
|
Definition
- Means that many band cells are in peripheral blood
- Signals acute stage infection |
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Term
| What types of patients often get Neutropenia? |
|
Definition
|
|
Term
| What is the M.O.A. of filgastrim (Neupogen)? |
|
Definition
| - Promotes proliferation, differentiation and activation of cells that makes granulocytes |
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|
Term
| What are indications of filgastrim (Neupogen)? |
|
Definition
| - Malignancies, chemo-induced leukopenia |
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|
Term
| What are the two types of Lymphocytes? |
|
Definition
|
|
Term
| Where are T. cells mature at?...and what do they do? |
|
Definition
- Mature in thymus
- Cell-mediated immune response (attack and destroy specific foreign cells) |
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|
Term
| Where are B. cells mature at?...and what do they do? |
|
Definition
- Mature in bone marrow
- Produce antibodies that react against foreign antigens (ex. Bacteria and Viruses) |
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Term
| What are Monocytes Major Function? |
|
Definition
- Protein phagocytosis (Fight bacteria similair to neutrophils)
- 2nd to arrive at scene of an injury (occur during late phase of infection) |
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|
Term
| What are Eosinophils Major Function? |
|
Definition
- Phagocytosis of antigen-antibody complexes
- Increase w/ allergic reactions and parasitic infections |
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|
Term
| What are Basophils Major Function? |
|
Definition
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