Term
|
Definition
|
|
Term
| Macrolide Antibiotics (Clarithromycin/Erythromycin) |
|
Definition
CYP3A4 SUBSTRATES
CYP3A4 INHIBITORS
|
|
|
Term
| Statins (Not pravastatin or rosuvastatin) |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Glucocorticoids (ex: Prednisone) |
|
Definition
CYP3A4 SUBSTRATE
CYP3A4 INHIBITOR |
|
|
Term
|
Definition
|
|
Term
|
Definition
CYP1A2 SUBSTRATE
CYP1A2 INHIBITOR |
|
|
Term
|
Definition
CYP2C19 SUBSTRATE
CYP2C9 SUBSTRATE
CYP3A4 INDUCER |
|
|
Term
Omeprazole
Lansoprazole
Esomeprazole
Pantoprazole
Rabeprazole |
|
Definition
CYP2C19 SUBSTRATE
CYP2C19 INHIBITOR (NOT ESOMEPRAZOLE) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
CYP3A4 INHIBITOR
CYP1A2 INHIBITOR
CYP2C9 INHIBITOR |
|
|
Term
| Azole Antifungals (Ketoconazole, Voriconazole) |
|
Definition
CYP3A4 INHIBITOR
CYP2C19 INHIITOR(KETO)
CYP2C9 INHIBITOR (VORI)
|
|
|
Term
|
Definition
CYP3A4 INHIBITOR
CYP1A2 INHIBITOR
CYP2C19 INHIBITOR
|
|
|
Term
|
Definition
|
|
Term
| Protease Inhibitors (Ritonavir, nelfinavir, indinavir) |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
CYP3A4 INDUCER
CYP2C19 INDUCER |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
CYP3A4 INDUCER
CYP2C19 INDUCER
CYP2C9 INDUCER |
|
|
Term
|
Definition
|
|
Term
|
Definition
CYP3A4 INDUCER
CYP2C9 INDUCER |
|
|
Term
|
Definition
CYP 3A4 INHIBITOR
CYP2C19 INHIBITOR
CYP2C9 INHIBITOR |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Increased effect of warfarin |
|
|
Term
|
Definition
|
|
Term
|
Definition
Decrease Clearance
Increase INR |
|
|
Term
| Chronic Heavy Alcohol Use |
|
Definition
Increase metabolism
Decrease INR |
|
|
