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VT 150 - week 4
VT 150
193
Veterinary Medicine
Not Applicable
11/16/2014

Additional Veterinary Medicine Flashcards

 


 

Cards

Term
F=1.8C+32
Definition
C=F-32/1.8
Term
Antimicrobial Drugs
Definition
counteract infection
Term
antimcrobials
Definition
chemical substances that have the capacity to kill or hinhibit the growth of microorganisms
Term
biocidal
Definition
kill microorganisms
Term
biostatic
Definition
inhibit the frowth of microorganisms
Term
antibiotics
Definition
chemicals that work on bateria
Term
spectrum of action
Definition
the range of bacteria on which the agent is effective
Term
gram (+) bacteria
Definition
resist decolorization by gram stain process (stains purple)
Term
Gram (-)
Definition
decolorized by gram stain process (stain pink-red)
Term
narrow spectrum antibiotic
Definition
drug specified for either gram (+) or gram (-)
Term
broad spectrum antibiotics
Definition
drugs used for both Gram (+) and Gram (-)
Term
bacteriostatic
Definition
drugs that inhibit the growth or replication of the organism
Term
bacteriocidal
Definition
drugs kill the organism
Term
goal of antibiotic therapy
Definition
render the bacteria helpless without causing harm to the patient
Term
Kirby Bauer Test
Definition
antibiotic disc test to determine sensitivity
Term
R = resistant
Definition
the antibiotic does NOT work against these bacteria
Term
I = intermediate
Definition
antibiotic may work against these bacteria
Term
S = sensitive
Definition
antibiotic DOES work against these bacteria
Term
MIC
Definition
minimum inhibitory concentration
Term
Minimum Inhibitory Concentration
Definition
the lowest concentration of an antibiotic that will at least inhibit the growth of bacteria
Term
Inhibition of cell wall synthesis
Definition
bactericidal
Term
damage to cell membrane
Definition
bactericidal or bacteriostatic
Term
inhibition of protein synthesis
Definition
bactericidal or bacteriostatic
Term
interference with metabolism
Definition
bacteriostatic
Term
impairment of nucleic acids
Definition
bactericidal
Term
antibiotic resistance
Definition
occurs when bacteria change in some way that reduces or eliminates the effectiveness of the medication
Term
antibiotic resistance occurs when:
Definition
medication is not used properly
used with a viral infection
improper dose or improper length of time
Term
antibiotic residues
Definition
presence of a chemical or its metabolites in animal tissues or food products
Term
even at low levels residues can cause allergic resistance that's transferred to people who consume food
Definition
withdrawl time
Term
classes of antibiotics
Definition
cell wall agents
cell membrane agents
protein synthesis agents
antimetabolites
nucleic acid agents
miscellaneous
Term
cell wall agents
Definition
affect the cell walls of bacteria & do not attack the host since animal cells do not have cell walls
Term
cell wall agents (examples)
Definition
penicillins
cephalosporins
bacitracin
vancomycin
Term
penicillin
Definition
natural & synthetic derivatives of molds
broad spectrum drug
beta-lactum structure that interfers with cell wall synthesis in newly formed bacteria
Term
penicillins (examples)
Definition
penicillin G (most common, narrow spectrum)
Penicillin Procaine G
Benzathine Penicillin G (provides longer blood levels)
Term
Penicillin Broad spectrum examples
Definition
amoxicillin
ampicillin
methicillin
Term
Penicillin Beta-lactamase resistant penicillins (narrow spectrum) examples
Definition
oxacillin
floxacillin
Term
Potentiated penicillins
Definition
(combined w/ another drug to enhance the effects of both)
amoxicillin/clavulanic acid
clavamox & augmentin
Term
Cephalosporins (1st - 4th generations)
Definition
semi-synthetic, broad spectrum antibiotics that interfere with cell wall synthesis
cephadroxil (cefa-drops)
cephalexin (keflex)
cefazolin
Term
bacitracin
Definition
disrupts the cell wall but by a different mechansim
toxic to kidneys
used as topical for skin, mucous membranes, eyes
also used a food additive
works against Gram + bacteria
Term
vancomycin
Definition
used against many gram + bacteria on infections that are resistant to toxic antibiotics such as penicillins or cephalosporins
Term
cell membrane agents
Definition
attack the cell membrane of the bacteria
Polymyxin B - usually combined w/ neomycin & bacitracin to create a wide spectrum topical medication
Term
protein synthesis agents
Definition
agents that interfere with the protein synthesis (DNA transmittance) in the bacterial cell
Term
protein synthesis agents
Definition
aminoglycosides
tetracyclines
chloramphenicol
florgenical
macrolides
lincosamides
Term
aminoglycosides
Definition
derived from species of streptomyces microbes
used to treat gram - bacterial infections
poorly absorbed from GI tract
highly toxic to kidneys
identified by -mycin, -micin ending in generic name
Term
Aminoglycosides (examples)
Definition
gentamicin
neomycin
amikacin
Term
tetracyclines
Definition
broad spectrum
bacteriostatic
slows bone development & causes discoloration of teeth
not approved for dairy cattle
-cycline ending in generic name
Term
tetracyclines (examples)
Definition
tetracycline
doxycycline - used in treatment of kennel cough, tick fever, lyme disease
Term
chloramphenicol
Definition
Broad spectrum
suppresses blood cell formation in bone marrow
banned from use in food-producing animals
wear gloves when handling
Term
florfenicol
Definition
synthetic
broad spectrum
used to treat bovine respiratory disease
Term
macrolides
Definition
can cause upset stomach
erythomycin
tylosin
tilmicosin
Term
erythromycin
Definition
bactericidal or bacteriostatic depending on concentration
used to treat penicillin-resistant bacteria
Term
tylosin (tylan)
Definition
used in livestock
can be found in food/water additives
not for use in horses
Term
tilmicosin
Definition
used to treat vocine respiratory disease
Term
lincosamides
Definition
work against gram (+) bacteria
Lincomycin
clindamycin (Antirobe) often used for dental infections
Term
antimetabolites
Definition
deprive bacteria of essential material needed for metabolism
Term
sulfonamides
Definition
inhibit synthesis of folic acid / hinders growth of bacteria
combined with trimethoprim & ormetoprim
side effects - skin rash, crystalluria, KCS
Term
sulfonamides (examples)
Definition
sulfadimethoxine (albon)
sulfadimethoxine/ormetroprim (primor)
Term
nucleic acid agents
Definition
interferes with bacterial nucleic acid
Term
fluoroquinolones
Definition
newer generation of quinolones
identified by -floxacin ending in generic name
can cause cartilage defects in frowing dogs
given at high doses, can cause blindness in cats
effective against gram + and gram - bacteria
Term
flouroquinolones (examples)
Definition
enrofloxacin (baytril)
ciprofloxacin (cipro)
orbifloxacin (orbax)
marbofloxacin (zeniquin)
Term
nitrofurans
Definition
broad spectrum
less potent than other antibiotics
prohibited from use in food animals b/c may induce carcinogenic residues in animal tissue
Term
nitrofurans (examples)
Definition
nitrofurazone
nitrofurantoin
Term
nitroimidazoles
Definition
antibacterial & antiprotozoal properties
commonly used to treat diarrhea
metronidazole (flagyl)
Term
rifampin
Definition
broad spectrum
used primarily w/ erythromycin to treat infections in foals
may cause reddish color to urine, tears, sweat, & saliva
Term
antifungals
Definition
divided into molds & yeast
Term
Superficial fungal infections
Definition
diagnosed through test media or microscopic identification
Term
Systemic fungal infections
Definition
identified through serology
Term
types of antifungals
Definition
polyene
imidazole
antimetabolic
superficial
Term
polyene antifungals
Definition
bind to fungal cell membrane
nystatin (panalog)-administered topically, orally, IV
Amphotericin B - administered IV, topically, extremely nephrotoxic
Term
imidazole antifungals
Definition
cause leakage of fungal cell membrane
have fewer side effects than amphotericin b
identified by -azole ending in generic name
Term
Imidazole antifungals (examples)
Definition
ketoconazole
miconazole
itraconazole
fluconazole (treats valley fever)
Term
antimetabolic antifungals
Definition
given orally & topically in combination with other antifungals to treat cryptococcus infections
Flucytosine
Term
Superficial Antifungals
Definition
Griseofulvin - treats dermatophyte infections (ringworm)
Lufeneron (Program)
Term
Antivirals
Definition
limited use in vet med
work by preventing viral penetration of the host cell
inhibiting virus production of RNA or DNA
Term
antiviral (examples)
Definition
Acyclovir - used to treat ocular feline herpes virus
Tamiflu - sometimes used to treat parvo
Interferon - used to treat FeLV & ocular feline herpes
Term
disinfectant
Definition
kills or inhibits growth of mocroorganisms on inanimate objects
Term
antiseptic
Definition
kills or inhibits growth of microorganisms on living tissue
Term
germicide
Definition
chemical that kills microorganisms
Term
bactericidal
Definition
chemical that kills bacteria
Term
virucidal
Definition
chemical that kills viruses
Term
fungicidal
Definition
chemical that kills fungi
Term
sporicidal
Definition
chemical that kills spores which are especially resistant to chemicals
Term
Types of disinfecting agents
Definition
Phenols
Quaternary Ammonium Compounds
Aldehydes
Ethylene oxide
Halogens
Biguanides
Other
Term
Phenols
Definition
first antiseptic effective against Gram + bacteria & some Gram - bacteria, fungi, & some enveloped viruses
Not effective vs. spores & nonenveloped viruses (such as parvo)
Should not be used as an antiseptic due to skin irritation & possible neurotoxicity
LYSOL
Term
Quaternary Ammonium Compounds
Definition
Effective vs. Gram + & Gram - bacteria
not effective vs spores
limited effectiveness vs fungi
effective vs enveloped viruses but not nonenveloped viruses (such as parvo)
Usually not irritating to skin
Example : Roccal-D
Term
Aldehydes
Definition
Gluteraldehydes used to disinfect instruments in cold sterilization & on fiberoptics
Sporicidal
Term
Formaldehydes
Definition
used to disinfect instruments in gas or solution
can be used as tissue fixation agent
Term
ethylene oxide
Definition
gas used for chemical sterilization
Term
alcohols
Definition
used on Gram + and Gram - bacteria
used vs. enveloped viruses
not for antiseptic purposes
causes pain and has denaturing effect on proteins
usually 70% solution used
Term
Chlorine (Chlorox)
Definition
halogen
kills bacteria, fungi, viruses, & spores
found in bleach, usually used in a 1:10 dilution
Term
Iodine
Definition
halogen
usually mixed with water or alcohol to form brown solution
commonly used as topical antiseptics
Betadine
Povidine
Term
Biguanides
Definition
effective vs. bacteria, some fungi, & enveloped viruses
Term
hydrogen peroxide
Definition
kills anaerobic bacteria in deep wounds
limit use - can cause damage to tissue
Term
soaps / detergents
Definition
limited bactericidal activity
main function is mechanical removal of microbes
Term
ectoparasites
Definition
live on the surface of the host
cause external parasite infestations
Term
endoparasites
Definition
parasites live inside the body
cause internal parasite infections
Term
helminths
Definition
worms found primarily in GI tract, liver, lungs, circulatory system
Term
nematodes
Definition
slender, tube-like, non-segmented
transmitted by arthropods
roundworms (ascarids, trichurs, ancylostoma, strongyle, dirofilaria)
Term
Platyhelminths
Definition
can live in GI tract or other body tissues
cestodes - tapeworms (taenia, dipylidium, echinococcus
trematodes - flukes (paragonimus)
Term
antiparasitics
Definition
categorized by the type of parasite they work against
Term
anthelmintics
Definition
kill worm parasites
further categorized into - antinematodal, anticestodal, antitrematodal
Term
Antinematodal - Benzimidazoles
Definition
Interfere with worm's energy metabolism
given PO in repeated doses
Term
Thiabendazole
Definition
ascarids & strongyles
also has antifungal & anti-inflammatory effects
Tresaderm Otic
Term
Oxibendazole
Definition
horse dewormer
can cause lier toxicity in dogs
EQ Equine Wormer Paste
Term
Mebendazole
Definition
Ascarids, hookworms, & cestodes in horses dogs
Telmintic
Term
Fenbendazole
Definition
nematodes, hookworms, whipworms, taenia, giardia
used in small animals, horses, & food animals
not for use in lactating dairy animals
Panacur
Term
Probenzimadazoles
Definition
probiotics which are metabolized in the animals body to benzimidazole
Febantel - Drontal Plus
Term
Imidazothiazoles
Definition
anticholinergic to paralyze the parasite
treat ascarids, strongyles, whipworms, & hookworms
not ovicidal
Levamisole - Levasole
Term
Tetrahydropyrimidines
Definition
cholinergic agonists that mimic action of Ach - initial stimulation and paralysis of the worm
Examples: Pyrantel Pamoate (Nemex, Strongid-T)
Pyrantel tartrate
Morantel tartrate
Term
Organophosphates
Definition
used vs. both endoparasites & ectoparasites
horses - bots, nematodes, strongyles,pinworms
ruminants - strongyles
dogs/cats - hookworms, nematodes, whipworms
usually given as feed additive to cattle
USE WITH CAUTION IN ALL SPECIES
neurotoxic to parasites, can cause neurologic side effects in host animal
Examples: dichlorvos (Task), Coumaphos (Baymix)
Term
Piperzine
Definition
only eradicates ascarids in all species
essentially nontoxic, sold OTC
Examples: Hartz Health Measures Once-a-month Wormer
Term
Avermectins
Definition
causes paralysis & death in the parasite
Ivermectin - can cause adverse reaction in collies and collie crosses
"White feet do not treat"
Examples: Heartgard, Ivomec
Term
Cestodes
Definition
consist of a head (scolex), neck & segments (proglottids)
increase in length by producing new segments from the neck area (oldest segments are at the distal end of the worm)
attaches to intestinal wall by its scolex (must dislodge it as part of treatment)
Examples: Praziquantel, Droncit, Epsiprantel (Cestex), Fenbendazole
Term
Trematodes
Definition
Named for the area they infect
Have intermediat host, usually a snail
Examples: Clorsulon (Curatrem), Albendazole (Valbazen), Praziquantel
Term
Protozoa
Definition
single-celled parasites
Term
Coccidia
Definition
protozoa that cause various intestinal disorders, some serious, even fatal
complex life cycle making them difficult to treat
treatment includes sanitation & disinfection of environment
Term
Anticoccidials - SULFA drugs
Definition
work at various stages of coccidian life cycle
usually given orally in feed, water, or by liquid and tablets
Term
Sulfamethoxine (albon
Definition
used in poultry, dogs, and cats
reduces the number of oocysts shed
Term
Amprolium
Definition
Corid
coccidiosis in calves
Term
Monensin
Definition
Rumensin
used in cattle
Term
Decoquinate
Definition
Deccox
used in cattle and goats
Term
Giardia
Definition
protozoan parasite seen in animals
treated with - Metronidazole (Flagyl), Fenbenazole (Panacur), Albendazole
Term
Babesia spp
Definition
blood protozoan transmitted by ticks
treated with imidocarb (imizol)
not used in food-producing animals
Term
Heartworm
Definition
affects dogs, cats, ferrets
caused by the nematode dirofilaria immitis
transmitted by mosquitos
adults live in the pulmonary artery but can be found in RT ventricle and RT atrium
Term
Heartworm medications
Definition
L3 can be prevented from reaching maturity by the use of preventative medicines
when given to a HW neg. dog the drug will prevent any larvae transmitted by a mosquito from reaching the adult stage
when given at hight doses it will also kill circulating microfilariae in HW pos dogs
Term
Ivermectin (Heartgard)
Definition
monthly preventative, given orally
also used to treat demodex
when given with pyrantel pamoate=Heartgard Plus
Dose determines use - Low - HW preventative
Moderate - kills microfilariae
high - kills most internal parasites
Term
Milbemycin (interceptor, Sentinel)
Definition
monthly preventative
both products are also effective vs. hookworms, nematodes, and whipworms
Sentinel also contains lufenuron for flea control
Term
Selamectin (revolution)
Definition
monthly preventative
applied topically and absorbed systemically
also controls fleas, ear mites, sarcoptic mange
some tick preventative activity
Term
Moxidectin (ProHeart-6)
Definition
six month injection interrupts early larval development
was taken off the market, but available again
Term
Melarsomine (immiticide)
Definition
arsenical drug given IM in epaxial muscles between L3 & L5
Term
Thiacetarsamide (caparsolate)
Definition
rarely used anymore, if at all
Term
adulticides - heartworm medications
Definition
used to treat any adult heartworms that may have developed in the RV because of improper or no preventatives
Term
Ivermectin
Definition
given at a higher dose
need to monitor for neurolofic side effects
Term
Ectoparasites
Definition
live on the outside of the body - flies, grubs, lice, fleas, mites, ticks, mosquitoes
accurate id of the ectoparasite is essential for proper treatment
can be oral, sprays, dips, pour-ons, ear tags, spot-ons, shampoos, dusts, foggers
always read product lave and use proper protective gear
Term
Nonspecific immunity
Definition
initial defense
physical barriers (skin), mucus production, inflammation, fever, phagocytosis of foreign material
Term
specific immunity
Definition
defense vs. specific antigen
B and T-lymphocytes
four types Active, passive, natural, artificial
Term
active immunity
Definition
arises when an animal receives an antigen that activates b and t-lymphocytes and causes the animal to produce antibodies
takes time to develop, but lasts a relatively long time due to memory
Term
passive immunity
Definition
arises when an animal receives antibodies from another animal
provides immediate protection, but for a shorter amount of time
Term
natural immunity
Definition
acquired during normal biological experiences
Term
artificial immunity
Definition
acquired through medical procedures
Term
vaccines trigger specific immune responses to help fight future infections from a specific agent
Definition
Term
vaccines
Definition
suspension of weakened, live, or killed microorganisms administered to prevent, improve or treat an infectious disease
Term
types of vaccines
Definition
inactivated (killed)
attenuated (modified-live)
live
recombinent
toxoids
antitoxins
antiserum
autogenous
multiple-antigen vaccines
Term
Inactivated (killed)
Definition
made from microorganisms or their components that have been chemically treated to kill the microorganism
advantages - usually safe, stable and unlikely to cause disease
disadvantages - need for repeated doses to ensure protection, adjuvant/preservatives may cause reaction
Term
attenuated (modified-live)
Definition
microorganisms have been altered to lose their virulence, but are still able to replicate w/in the animal to provide immunity
advantages - immunity usually lasts longer, have better efficacy and quicker stimulation of CMI
disadvantages - possible abortion when given to pregnant animal, can produce mild forms of the disease, can be shed into the environment
Term
live
Definition
made from live microorganisms that may be fully virulent or avirulent
advantages - fewer doses are needed to achieve immunity, lasts longer, adjuvants not needed, inexpensive
disadvantages - possible residual virulence
Term
recombinant
Definition
a gene or part of a microorganism is removed from one organism (pathogen) and inserted into another microorganism
advantages - fewer side effects, effective immunity, varied routes of administration
disadvantages - increased cost
Term
toxoids
Definition
special type of vaccine used vs. toxins instead of microorganisms
used like a vaccine
provides active immunity
disadvantages-shorter duration of effectiveness, may contain adjuvants/preservatives
Term
antitoxins
Definition
substances that contain antibodies obtained from an animal that has been hypersensitized to neutralize toxins
used when exposure to a toxin is likely
provides passive immunity
disadvantages- immunity short-lived, may also contain preservatives
Term
antiserum
Definition
antibody-rich serum from a hypersensitized or actually infected animal
abs are collected from plasma
short lived (passive)
treats k9 distemper, feline panleukopenia, bovine anthrax
Term
autogenous
Definition
produced for a specific disease problem in a specific area from a sick animal
cultured organism from farm
disadvantages - may contain endotoxin or other byproducts so use with caution
Term
polyvalent vaccines
Definition
multiple-antigen vaccines contain more than one antigen
advantages-fewer injections to administer, less expensive when giving multiple vaccine agents
disadvantages- rate of adverse reactions rise as the number of antigens goes up
Term
care and handling of vaccines
Definition
sensitive to sunlight, excessive heat and freezing
store in refrigerator
obtain from a reputable source
some vaccines need to be reconstituted prior to use, use only diluent provided by manufacturer
administer only via route identified by manufacturer (especially important in food animals)
do not mix multiple vaccines together in same syringe
administer different vaccines in different sites and record where/how given
Term
patient considerations
Definition
age
health
medications
pregnancy
environment
history
Term
local vaccine reactions
Definition
pain, swelling at injection site
Term
systemic vaccine reaction
Definition
anaphylaxis, hives, wheezing, dyspnea, hypotension, shock
Term
sarcomas
Definition
tumors of connective-tissue origin
Term
antibody titers
Definition
way to assess the level of antibody to particular antigen
expressed in ratios such as 1:2, 1:4
the correlation between antibody titer and protection vs. exposure to the disease has not been thoroughly investigated
Term
core vaccine
Definition
recommended for all individual animals because:
the consequences of infection are severe
infection poses zoonotic potential
disease prevalence is high
organism is easily transmitted to others of its species
vaccine is safe and efficacious
examples: rabies, DHPP, FRCP
Term
noncore vaccines
Definition
recommended only for individual animals deemed to be at high risk for contact with the organism
based on evaluation of all risk factors
Example: Bordetella
Term
cancer-fighting drugs
Definition
antineoplastic and chemotherapeutic agents stop the cancerous activity of malignant cells
Term
act vs. characteristics unique to malignant cells
Definition
rapid cell division
different rate of cellular drug uptake
increased cellular response to selected anticancer drugs
Term
Cell-cycle nonspecific (CCNS)
Definition
antineoplastic agents that act during any phase of the cell cycle
kill the cell during the dividing or resting phases
Term
cell-cycle specific (CCS)
Definition
antineoplastic agents that act during a specific phase of the cell cycle
effective against rapidly growing cancer cells
Term
growth fraction
Definition
the percentage of the cancer cells that are actively dividing
high growth fraction = cells are dividing rapidly
low frowth fraction = cells are dividing slowly
Term
doubling time
Definition
time required for the number of cancer cells to double
Term
CCNS drugs
Definition
kill at any phase concentration dependent killing
Cyclophosphamide (Cytoxan)
Cisplatin
Caboplatin
Doxorubicin (adriamycin)
steroids - corticosteroids, estrogens, androgens
Term
CCS - cell-cycle specific
Definition
kill in specific phases of cell cycle; killing is time dependent
5-fluorouracil
vincristine
vinblastine
Term
administering antineoplastics
Definition
various protocols are used-some in therapeutic combinations the tumor is more effectively destroyed when bombarded w/drugs that act in different ways
calculation of antineoplastics is based on body surface area
BSA is determined from bodyweight in kg using charts
Term
safe handling of antineoplastics
Definition
waste is considered contaminated for 72 hr and disposed of properly
reconstitution of agents is done in a vertical airflow hood with PPE
IV catheter placement must be a "good stick" and some area not used again w//in a 24 hour period
Pregnant women should not handle antineoplastics
immuno-compromised people should not handle antineoplastics
NO eating/drinking while handling drugs
Term
immune enhancers
biologic response modifiers (BRMs)
Definition
agents used in conjunction with antineoplastic agents to enhance body's immune system
Term
interferons
Definition
group of naturally-occurring proteins that have antitumor and antiviral effets
Term
Interleukins
Definition
group of chemicals that play various roles in the immune system
Term
acemannan
Definition
chemical used in treatment of fibrosarcomas and MCTs (mast cell tumors) in dogs and cats
stimulates macrophage activity
Term
monoclonal antibodies
Definition
identical immunoglobulin molecules that have cytotoxic effects on tumor cells
Term
immunosuppressive drugs
Definition
work mainly by interfering with one of the stages of the cell cycle or by affecting cell messengers
Used primarily to treat immune-mediated disorders in which the immune system is overactive
Examples:
Cyclosporine (Atopica, Optimmune)
Azathioprine (Imuran)
Cyclophosphamide (Cytoxan)
Term
L-asparaginase (elspar)
Definition
works by making asparagine unavailable to malignant cells
Term
Enzyme Inhibitors
Definition
controls the growth of tumor cells
Toceranib (Palladia)- treats Grade II and III, recurrent, cutaneous mast cell tumors in dogs, given in tablet form, owners should wear gloves and wash hands
Term
Adverse reactions
Definition
bone marrow suppression
GI effects
alopecia
infertility
cardiotoxicity
Term
opthalmic drug considerations
Definition
1-drug penetration-topical opthalmic drugs tend to be absorbed into the anterior chamber and have little effect on the posterior or vitreous chambers
2-frequency of drug application-ointments are usually administered less frequently than eye drops
3-ease of application-some clients find ointments easier to apply than drops and vice cersa
Term
topical anesthetics
Definition
used for foreign body removal and performance of comprehensive eye exams
Examples: proparacaine, tetracaine
Term
fluorescein sodium
Definition
detects corneal defects and patency of lacrimal ducts
Term
Pupil Closing (miotics)
Definition
cholinergic drugs that constrict the pupil
lower introcular pressure by increasing outflow of aqueous humor
used for glaucoma
Example - Pilocarpine
Term
Pupil Opening (Mydriatics)
Definition
drugs that dilate pupils
may be used to treat uveitis and to dilate pupil for fundic exam
Examples: atopine, homatropine, phenylephrine, tropicamide, epinephrine
Term
cyclopedics
Definition
drugs that paralyze the ciliary muscles and may minimize pain due to ciliary spasm
Term
glaucoma
Definition
disease characterized by increased IOP due to structural defects, genetic defects, or result of other ocular disease or trauma
If left untreated, could cause blindness
drugs to treat glaucoma reduce IOP by decreasing production of fluids w/i the eye
Examples: carbonic anhydrase inhibitors, beta-adrenergic blockers, osmotic diuretics
Term
keratoconjunctivitis sicca (KCS, "dry eye")
Definition
tear production is decreased resulting in persistent mucopurulent conjunctivitis and corneal scarring and ulceration
may be immune mediate
treatment includes: artificial tears, antibiotic-steroid preparations, lacrimogenics (increase tear production), immunomodulators
Term
Otitis externa
Definition
inflammation of the pinna dna external auditory canal
caused by bacteria, yeast, parasites, allergiew, systemic disease, and neoplasia
clinical signs = head shaking, ear scratching, ear discharge
Term
otitis media
Definition
inflammation of the middle ear
caused by extension of otitis externa through ruptured tympanum, URI, polyps, trauma
can be clinically silent or have signs similar to otitis externa
Term
otitis interna
Definition
inner ear infection
signs = head tilt toward the affected side, ataxia, nausea, and vomiting
Term
diagnosing otitis
Definition
otoscopic exam
ear cytology
culture / sensitivity
Term
otic medications
Definition
combo of antifungal, antibiotic, and antiinflammatory
antiparasitics are used to treat ear mites
local anesthetics reduce pain
cleansers, drying agents and cerumen (ear wax) dissolvers are used in combo with otic medications
Term
Otic Medications (examples)
Definition
Tresaderm
Otomax, Mometamax
Panalog
Baytril Otic
Conofite
MilbeMite
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