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visceral motor
visceral motor
90
Anatomy
Graduate
04/25/2012

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Term
who's the boss of visceral motor activity
Definition
hypothalamus
Term
what is another term for visceral motor system
Definition
autonomic motor system
Term
what is the function of the visceral motor system
Definition
controls involuntary functions mediated by the activity of smooth muscle, cardiac muscle, and glands
Term
what are the 2 major divisions of the visceral motor system
Definition
sympathetic, parasympathetic
Term
funciton of sympathetic division of visceral motor system
Definition
mobilizes body's resources for dealing with challenges
Term
function of parasympathetic division
Definition
activity predominates during states of relative quiescence so energy can be restored: Rest and Digest
Term
where do parasympathetic preganglionic neurons origintate
Definition
either in the brainstem or in the sacral region of the spinal cord
Term
where do sympathetic preganglionic neurons originate
Definition
T1-L2
Term
what are the 4 brainstem nuclei from which parasympathetic neurons arise
Definition
edinger-westphal nucleus, superior & inferior salivatory nuclei, dorsal motor nucleus of vagus, nucleus ambiguus
Term
which preganglionic parasympathetic neurons originate in the edinger-westphal nucleus
Definition
parasympathetic fibers of the oculomotor nerve (CN III)
Term
which preganglionic parasympathetic neurons originate in the superior and inferior salivatory nuclei
Definition
parasympathetic fibers of CN VII and IX
Term
which preganglionic parasympathetic neurons originate in the dorsal motor nucleus of the vagus
Definition
parasympathetic fibers of vagus
Term
which preganglionic parasympathetic neurons originate in the nucleus ambiguus
Definition
additional parasympathetic fibers that also project via the vagus nerve
Term
in what part of the brainstem is the edinger westphal nucleus
Definition
midbrain
Term
in what part of the brainstem is the dorsal motor nucleus
Definition
medulla
Term
specifically where in the sacral spinal cord do parasympathetic preganglionic neurons arise from (what horn, what levels
Definition
lateral horn of the gray matter of spinal cord between S2-S4
Term
what is the path of the preganglionic parasympathetic neurons that originate in the lateral honr of the gray matter of the spinal cord between S2-S4
Definition
the axons of these neurons travel via pelvic splanchnic nerves to innervate parasympathetic ganglia in the lower 1/3 colon, rectum, bladder, and reproductive organs
Term
what nerve innervates the upper viscera
Definition
vagus
Term
what innervates lower viscera
Definition
splanchnics from sacrum
Term
what are some parasympathetic activities
Definition
constrict pupils, slow heart rate, increase peristaltic activity of the gut, increase glandular secretions
Term
what is the enteric nervous system
Definition
an extensive system of independent nerve cells associated with the gastrointestinal tract
Term
do more neurons reside in the human GI tract or in the spinal cord?
Definition
more in the human GI tract
Term
if you want to consider that the visceral motor system has 3 divisions, what are its 3 divisions
Definition
sympathetic, parasympathetic, enteric
Term
what is the function of the Enteric Nervous System
Definition
enteric neurons work somewhat independently of the visceral motor system and help control mechanical and chemical conditions within the gut
Term
where are intrinsic enteric neurons located?
Definition
within the walls of the GI tract in 2 major plexuses: Auerbach's and Meissner's
Term
what are the 2 major plexues of the enteric nervous system
Definition
Auerbach's and Meissner's
Term
what is another term for Auerbach's plexus
Definition
myenteric plexus
Term
what is the function of the neurons of the myenteric plexus
Definition
regulate peristalsis/muscular control of the guty
Term
what is another name for meissner's plexus
Definition
submucus plexus
Term
what is the function of neurons of the submucus plexus
Definition
chemical monitoring and glandular secretions
Term
what 3 neuronal systems control GI functions
Definition
enteric, parasympathetic, sympathetic
Term
where does parasympathetic innervation to the GI come from
Definition
dorsal motor nucleus of the vagus
Term
where does sympathetic innervation to the GI tract come from
Definition
sympathetic neurons from spinal cord byway of celiac and mesentary prevertebral ganglia
Term
can the enteric system function without vagus and without sympathetics
Definition
yes. It will still actively digest and move food along.
Term
what are GVA neurons
Definition
neurons that bring infromation back from viscera to CNS
Term
does the visceral motor system require sensory feedback?
Definition
yes: to modulate and control its many functions
Term
where are the cell bodies of many visceral afferents (GVA neurons) located
Definition
in small ganglia along the vagus nerve
Term
where do axons of GVA neurons project centrally
Definition
into the solitary nucleus of the brainstem
Term
what does the soliatary nucleus do once it has received sensory information from GVA neurons
Definition
integrates the sensory information and projects it onto the hypothalamus for further integration
Term
what is the key controlling center for autonomic function
Definition
hypothalamus
Term
what are some examples of visceral afferent information that the GVAs bring up to the CNS
Definition
nausea, GI distention due to overeating, pulse rate, respiration rate, blood pressure, how full the bladder/bowel is
Term
what is the major organizing center for visceral motor function
Definition
hypothalamus
Term
what part of the brain does the hypothalamus belong ot
Definition
diencephalon
Term
what is the hypothalamus continuous with
Definition
pituitary gland
Term
what makes up the hypothalamus
Definition
large number of nuclei - each with their own pattern of connections and functions
Term
what is the key controlling center for general homeostatic funcitons
Definition
hypothalamus
Term
what is the path of GVA information, beginning with the vagus
Definition
vagus - NST - hypothalamus
Term
along with GVA information, what else projects to the hypothalamus
Definition
cerebral cortex amygdala, solitary nucleus
Term
what is another term for solitary nucleus
Definition
nucleus of the solitary tract = NST
Term
what does the hypothalamus do with all of the information/projections it receives
Definition
hypothalamic nuclei synthesize converging information and then project appropriate responses to preganglionic sympathetic and parasympathetic neurons in the brainstem and spinal cord
Term
what types of information does the hypothalamus integrate
Definition
visceral, cognitive, emotional
Term
what is the job of the hypothalamic nuclei
Definition
receive/integrate afferent stimuli and relay visceral motor responses
Term
describe the path of visceral info as it leaves organs as sensory and returns as motor
Definition
GVA from organs goes to the nucleus of the solitary tract. NST goes to hypothalamus. Hypothalamus integrates visceral sensory info with cognitive and emotional info. From the hypothalamus, it will activate either sympathetic or parasympathetic nerves to contro viscera.
Term
why is it that something I see can make me throw up
Definition
info from what you see goes to the hypothalamus. The hypothalamus controls vomiting centers
Term
what types of neurons leave the hypothalamus to go to the organs (GVA, GVE, GSA, GSE
Definition
GVE
Term
from where (directly) does the hypothalamus receive visceral sensory information
Definition
nucleus of the solitary tract = NST
Term
is the hypothalamus the boss of sympathetics or parasympathetics
Definition
both
Term
what are the basics of what the hypothalamus does
Definition
receives information from organs. Integrates it with cognitive/emotions. Sends direct responses down parasympathetics or sympathetics
Term
what 2 neurotransmitters does the visceral motor system use
Definition
acetylcholine and/or norepinephrine
Term
what is the primary neurotransmitter of sympathetic and parasympathetic preganglionic neurons
Definition
acetylcholine
Term
what are the 2 types of receptors that acetylcholine can activate on postganglionic neurons
Definition
nicotinic (nAChR) and muscarinic (mAChR)
Term
describe nAChR
Definition
ionotropic ion channels that mediate fast excitatory postsynaptic potentials
Term
describe mAChR
Definition
G-protein-linked receptors that mediate slower but prolonged postsynaptic potentials
Term
what neurotransmitter do sympathetic preganglionic neurons use
Definition
acetylcholine
Term
what neurotransmitter do parasympathetic preganglionic neurons use
Definition
acetylcholine
Term
which acetylcholine receptors mediate fast excitatory postsynpatic potentials on the postganglionic cell
Definition
nicotinic (nAChR)
Term
which acetylcholine receptors mediate slow, prolonged postsynpatic potentials on the postganglionic cell
Definition
muscarinic (mAChR)
Term
what is the result of acetylcholine being able to activate 2 kinds of receptors
Definition
preganglionic neurons can generate both rapid excitation and slower modulation on postganglionic neurons
Term
what kind of neurotransmitter is used by postganglionic sympathetic neurons
Definition
norepinephrine
Term
what is another term for norepinephrine
Definition
adrenalin
Term
what kind of neurotransmitter is used by postganglionic parasympathetic neurons
Definition
acetylcholine
Term
why is the postganglionic sympatheticsystem sometimes referred to as an adrenergic system
Definition
postganglionic sympathetics release adrenalin/norepinephrine onto their targets
Term
why is the postganglionic parasympathetic system sometimes referred to as an cholinergic system
Definition
postganglionic parasympathetics release acetylcholine onto their targets
Term
what determines the specific effects of acetylcholine and norepinephrine from the postganglionic neurons
Definition
the type of receptor expressed on the target tissue
Term
from where does the heart receive sympathetic innervation
Definition
from neurons originating in the lateral horn of the spinal cord
Term
from where does the heart receive parasympathetic innervation
Definition
from neurons originating in the dorsal motor nucleus of the vagus
Term
what is the function of sensory receptors in the heart
Definition
sensory receptors monitor blood pressure changes in the great vessels and this information is conveyed via vagus nerve to the NST
Term
what sensory receptors are in the heart
Definition
baroreceptors
Term
what neurotransmitter is released by preganglionic parasympathetic neurons that synapse on the heart
Definition
acetylcholine
Term
what happens if blood pressure increases?
Definition
deformation of baroreceptors in the great vessels is conveyed through the vagus nerve GVA fibers to the nucleus of the solitary tract. The NST relays this information to the hypothalamus for integration. The hypothalamus responds by inhibiting preganglionic sympathetic neurons in the spinal cord as well as by activating preganglionic parasympathetic neurons in the dorsal motor nucleus of the vagus. Inhibition of sympathetic neurons and activation of parasympathetic neurons prevents release of norepinephrine and causes a release of acetylcholine, thereby decreasing herat rate
Term
what is the result of inhibition of preganglionic sympathetics to the heart
Definition
reduced stimulation of postganglionic sympathetics and therefore reduced stimulatory effect of norepinephrine on cardiac muscle
Term
what is the result of activation of preganglionic parasympathetic neurons
Definition
activation of postganglionic parasympathetic acetylcholine release decreases heart rate and force of heart contractions
Term
bladder is under control of what 3 systems
Definition
somatic, sympathetic, parasympathetic
Term
what is the function of sympathetic activity on the bladder
Definition
throughout the day, tonic sympathetic activity closes the internal sphincter and allows the bladder to fill
Term
what is the function of somatic innervation to the bladder
Definition
somatic motor nerve (pudendal nerve) tonically closes an external sphincter to prevent voiding
Term
what are the nerve roots of the pudendal nerve
Definition
S234
Term
what is the pathway that tells you that you need to pee
Definition
as the bladder fills, visceral afferent neurons project to the spinal cord and ultimately to the nucleus of the solitary tract and pontine micturation centers in the brainstem
Term
what is the pathway that allows you to release urine from the bladder
Definition
hypothalamus/pontine micturation centers initiate descending pathways which inhibit the sympathetics and the pudendal nerve, which have been closing the sphincters. The hypothalamus/pontine micturation centers activate parasympathetics in the S234 spinal cord which cause bladder contraction.
Term
if you have a spinal cord injury, how do you release urine from your bladder
Definition
the ascending sensory information from the bladder as well as the descending motor information to the bladder has been cut off. However, once you get enough volume in the bladder, urination is stimulated reflexively by parasympathetic nerve at the sacral spinal cord level, causing bladder to empty incompletely
Term
what is the problem of incomplete emptying of the bladder in SCI patients
Definition
causes UTI
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