Term
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Definition
•Agent must be present in every case
•must be isolated and grown in vitro.
•disease must be reproduced when inoculated into a susceptible host.
same agent must be recovered from the experimentally infected host. |
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Definition
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Definition
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Definition
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Definition
| capsid plus nucleic acids |
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Term
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Definition
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Term
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Definition
| projections on an envelope, usually glycoproteins |
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Term
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Definition
cubic/ icosahedral
helical
binal
complex |
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Term
| DNA methods to increase genome coding capacity |
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Definition
| Open Reading Frames and differential splicing |
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Term
| RNA methods to increase genome codign capacity |
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Definition
positive and negative sense
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Term
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Definition
| same sequence as mRNA doesn't need to be transcribed |
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Term
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Definition
| complementary/opposite sequence of mRNA must be transcribed |
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Term
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Definition
| proteins that are part of the mature virion and are carried with it even outside of the cell. can include enzymes |
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Term
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Definition
| proteins encoded by the virus but not present on the viral particle |
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Term
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Definition
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Definition
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
| period of the growth curve where the virus has entered the cell but has not finished replication or left the cell yet |
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Term
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Definition
affinity for a specific type of tissue
determined by:
receptors on the cell
transcription factors
viral tropogens
physical environment |
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Term
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Definition
attachment
penetration
uncoating
transcription and/or translation
viral nucleic acid and protein synthesis
assembly and/or maturation
release by lysis (non enveloped) or budding (enveloped)
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Term
| mechanisms of viral entry |
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Definition
endocytosis - naked or enveloped
fusion - enveloped
translocation - naked |
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Term
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Definition
can undergo mRNA splicing
open reading frames, multiple proteins per mRNA |
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Term
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Definition
- use both strands
- genes overlap
- different open reading frame
- variation in termination and splicing
- polycistronic messages
- post translational processing |
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Term
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Definition
| exchange of nucleic acid between viruses |
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Term
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Definition
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Term
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Definition
| exchange of gene PRODUCTS between two viruses |
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Term
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Definition
| number of cases in a time period |
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Term
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Definition
| number of cases at one time point |
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Term
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Definition
| percent of population that contracts disease during an outbreak |
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Term
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Definition
| percent with disease that die |
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Term
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Definition
| disease occurse continuously in the population over a period of time |
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Term
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Definition
| peaks in disease occurence that exceed expected values |
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Definition
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Definition
direct
indirect
vector
iatrogenic
nosocomical
zoonotic
vertical |
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Term
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Definition
acute
recurrent
chronic
slow |
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Definition
| capacity to produce disease of any severity |
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Definition
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