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VIII Chemistry comes alive II
we love chem!!!
49
Anatomy
Undergraduate 2
09/16/2013

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Term
In physiological systems
Definition
we find inorganic and organic compounds that are reactive and interactive, store and release energy, structurally strong are catalyst
Term
What are the inorganic compounds
Definition
water, salts, acids, bases, buffer
CO2, CO3, CO
Term
water
Definition
polar molecule: electron hover around oxygen nucleus more
Term
Water; heat properties
Definition
absorb/lose heat; good for tempering effect in internal and external environmental changes
Term
solvent properties
Definition
polarity allows ions to dissolve in the water
Term
reactivity (water)
Definition
hydration and synthesis reaction, water used to breakdown products, removed during synthesis reaction
Term
Salts
Definition
ionic compounds with cations other than H+ and anions other than OH-
Term
electrolytes
anion
cations
Definition
ions; conduct current
anions is negatively charged
cations is positively charged
Term
Acids
Definition
proton H+ donor- dissociate in water
weak acids- do not completely dissociate
strong acids- completely dissociate
Term
Bases
Definition
proton (H+) acceptor
hdroxyl ion
weak bases- weak proton acceptors
strong bases- strong acceptors
Term
Organic compounds
Definition
carbohydrate, lipids, nucleic acids, proteins,
Term
Carbohydrates
CHO
Definition
Carbon + Hydrogen + oxygend 1:2:1
Term
monosaccharides
Definition
one chain or ring ribose, glucose, fructose
Term
disaccharides
Definition
2 rings joined; glucose and fructose to make sucrose, maltose, lactose
Term
polysaccharides
Definition
3 or more sugars: starch, cellulose, glycogen
Term
carbohydrate function
Definition
fuel for working muscles and organs
Term
Lipids
CHO
Definition
proportion of O is much lower than carbohydrates; also some phosphorus
Term
Neutral fats
glycerol
fatty acids
Definition
triglycerides
3 carbon
long carbon chains
Term
Saturated
Definition
no C-C double bonds, plaque formation and cardiovascular disease
Term
Unsaturated
Definition
at least one carbon double bond
Term
True or false, triglycerides are non polar covalent bond and don't dissolve in aqueous solutions
Definition
true
Term
Phospholipid
Definition
one fatty acid chain replaced by phosphate group
polar
interact with aqueous envrionemnt
**to change polarity and function of triglycerides add phopshate in place of fatty acid chain
Term
Steroids (type of steroid)
Definition
flat 4 hydrocarbon rings
cholesterol- membranes, bile slats, vitamin D and steorid hormones (estrogen, testosterone)
Term
Eicosanoid
Definition
lipid
20 carbon; prostaglandins found in inflammation, bloodclotting, labor...drugs inhibit production of prostaglandin
Term
Proteins
elements make up proteins
Definition
Carbon + Hydrogen + Oxygen and Nitrogen*
Term
Amino acids
Definition
building blocks of protein; 20
Term
Primary structure
Definition
amino end of one amino acid joins with acid end of 2nd amino acid. forms peptide bond
Term
secondary structure
Definition
alpha helix, beta sheet folding of protein due to amino acid chain arrangement
alpha helix is coil of primary chain; stabilized by hydrogen bonds
Beta sheets linked side by side through hydrogen bonds
Term
tertiary structure
Definition
helix/sheet folds over itself glob structure; enzymes' allows proximity of protein
Term
Quaternary structure
Definition
aggregation of two or more polypeptide chains
hemoglobin
4 different subunits in 1 protein --> non functional if pull apart different subunits
Term
Fibrous proteins
Definition
strand like; collagen, elastin, keratin,
structureal
important in tensile strength
skin cells have a lot of this
Term
globular proteins
Definition
spherical protein ; functional=enzymes
Term
denaturation
Definition
destruction of structure of the protein, heat or too much acid
Term
Enzymes
cofactor
coenzyme
Definition
characteristic- globular protein catalyst
small molecule need for enzyme to function effectively; Mg 2+ and Ca 2+
large organic cofactor; vitamin
Term
Mechanisms of enzyme activity
activation energy
substrate
active site
Definition
activation energy - energy needed to bring two molecules into reaction
substrate- bind to enzyme; reactnats
active site- where reactant bind to enzyme
Term
molecular chaperones
Definition
heat shock proteins
assist protein folding during synthesis
prevent incorrect folding
aid association process
translocation of protein across cell membranes
promote breakdown of damaged denatured protein
Term
Nucleic acids
elements:
Definition
C,H,O,N,P*

sugar (ribose/deoxyribose) nitrogen base (adenine, guanine, cytosine, thymine, uracil) phosphate group
Term
DNA
location
Definition
nucleus and mitochondrion
Term
DNA structure
Definition
double helix
Term
DNA stability
Definition
stable (not degrade easily(
Term
function of DNA
Definition
TEMPLATE for protein synthesis
Term
Elements
Definition
sugart deoxyribose bases: ATCG
phosphate backbone= sugar phosphate
Term
Complementary base pair
Definition
A:T
C:G
Term
RNA location
Definition
outside nucleus
Term
RNA structure
Definition
single stranded
Term
RNA stability
Definition
easily broken down
Term
RNA function
Definition
protein synthesis; mRNA, rRNA, amino acid carrier (tRNA)
Term
elements
complementary bases RNA
Definition
sugar: ribose, bases AGCU
A:U
C:G
Term
ATP
Definition
nucletoide with 2 additional phosphate groups
main energy currency for body
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