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Vertebrate Development Test 3 (Final)
Kempf
187
Biology
Undergraduate 4
12/07/2010

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Term
Neural Crest Cells arise from...
Definition
edges of forming neural plate.
Term
Neural Crest Cells have two migrations
Definition
1. dorsal lateral (superficial)
2. ventral (deep through somites)
Term
Neural Crest Cells in Cranial Region form (10)
Definition
1. sensory roots of CN 5,7,9,10
2. Schwann Cells of PNS
3. Brachial Cartilages
4. Membranous Bones of Skull
5. Mesoderm
6. Dentine of Teeth
7. Head Mesenchyme
8. Cranial parasympathetic Ganglia
9. Ciliary Muscle of Eye
10. Meninges of CNS (pia mater, arachnoid mater, dura mater)
Term
Neural Crest Cells of Trunk form...
Definition
1.Parasympathetic and Sympathetic Ganglia
2. Dorsal Root Ganglia
3. Meninges of CNS (pia, arachnoid, dura)
4. Schwann Cells of PNS
5. Adrenal Medulla
Term
Cranial Nerves
Definition
1. Olfactory
2. Optic
3. Oculomotor
4. Trochlear
5. Trigeminal
6. Abducens
7. Facial
8. Acoustic
9. Glossopharyngeal
10.Vagus
11.Accessory
11. Hypoglossal
Term
CN #1
Definition
Olfactory (Special Sensory)
Term
CN #2
Definition
Optic (special Sensory)
Term
#3
Definition
Oculomotor (motor)
Term
#4
Definition
Trochlear (motor)
Term
CN #5
Definition
Trigeminal (mixed)
*Gasserian Ganglia
Term
CN #6
Definition
Abducens (Motor)
Term
CN #7
Definition
Facial (mixed)
root ganglia- proximal
geniculate- distal
Term
CN #8
Definition
Acoustic (ss)
Vestibuloacoustic ganglia
Term
CN #9
Definition
Glossopharyngeal (mixed)
superior- proximal
petrosal- distal
Term
CN #10
Definition
Vagus (mixed)
jugular- proximal
nodose- distal
Term
CN #11
Definition
Accessory (motor)
Froieps ganglia
Term
CN #12
Definition
Hypoglossal (motor)
Term
Origins of Cranial Ganglia
Definition
1. Dorsolateral Placode
2. Epibrachial Placode
3. Neural Crest
(Cells from placodes= sensory or support cells)
Term
Colchicine
Definition
cause cells to lose shape (destroy microfilaments/ microtubules)
Term
Mitotic spindle in Neural Tube Cells
Definition
Vertical Axis initially and horizontal later
Term
3 Layers of Neural Tube
Definition
1. Ependymal - 1 cell thick, ciliated, circulate CSF
2.Mantle- Cell Bodies and Glial Cells
3. Marginal- aons and glial cells (stains darker)
Term
Oligodendrocytes (CNS) form from...
Definition
Neural Epithelium
Term
Schwann Cells (PNS) form from
Definition
Neural Crest Cells.
Term
Efferent=
Definition
motor
Term
Afferent=
Definition
Sensory
Term
Stereotropism
Definition
axons follow path of least resistance
1. Singer- axons follow holes/ tunnels
2. Silver/Sidman- parallel axons follow open path
3. Axons follow scratch in petri dish
Term
Deferential adhesion
Definition
axons grow along path of most adhesion
1. Letoureau- grid of palladium (non sticky) and Polyornithine (sticky)
Term
Galvanotropism
Definition
Axons pathfind along charge differential (in vitro)
**Patel
Term
Chemotropism
Definition
Pathfinding in response to chemical signals (in vitro)

-Attractants and Repellants
** Gunderson and Barrett
Term
EphB1-ECDs protein
Definition
initiates response of COLLAPSE and RETRACTION in Growth Cone of Retinal axons
Term
EphB2ECDs Protein
Definition
initiates response of FREEZING in Growth Cone of Retinal axons
Term
At birth, the human brain has
Definition
100 billion neurons and 1000 billion glial cells.
Term
The adult brain has
Definition
1,000 trillion synapses.
Term
Inductions of Olfactory Placode
Definition
1. Presump. Head endoderm
2. presump. Head mesoderm
3. telencephalon (seals fate)
Term
Lifespan of Neurons in Olfactory Epithelium
Definition
1 month (replaced by basal stem cells)
Term
Inductions of Otic Vesicle
Definition
1. Chordamesoderm
2. Paraxial (Somitomere) Mesoderm
**Somite Mesoderm of Head Region
3. Lateral Wall of Myelencephalon (Seals Fate)
Term
Eye Development in 33 Hour Chick/ 3 Week Human
Definition
Neuropores and Optic Vesicles Visible
Term
Eye Dev. in 36 Hr Chick/ 4-5 week human
Definition
Lens Placode induced by forming Optic Vesicles
- Placode Imm begins to invaginate
Optic Vesicles invaginate to form Optic Cup
Term
Eye Dev. in 7-8 Week Human
Definition
Optic Cups Closed
- Lens Vesicle Circle
-Optic Vesicles>>Lens Placode>> Optic Cups
Term
Choroid Fissure
Definition
Where blood vessels and nerves enter/ leave eye
Term
Optic Nerve arises from
Definition
neurons of SENSORY RETINA
Term
Pars Optica Retinae
Definition
Sensory Portion of Sensory Retina
Term
Pars Caeca Retinae
Definition
edges of Sensory Retina
Term
Pars Ciliaris
Definition
from Ciliary Body to Ora Serrata (groove)
Term
Pars Iridea
Definition
from Ciliary Body to Edge of Optic Cup
Term
Ciliary Body
Definition
Muscles controlling Lens shape
** Connected to Lens by Ligaments
Term
At 5-6 Weeks, Layers of Human Eye
Definition
Outer Neuroblastic Layer of Sensory Retina
Term
At 6-7 Weeks, Layers of Human Eye
Definition
Outer Neuroblastic Cells begin dividing and move deeper to form INNER NEUROBLASTIC LAYER
Term
At 7-8 Weeks, Layers of Human Eye
Definition
Inner Neuroblastic cells begin to divide and move in to form inner most Neuron Layer
Term
Outer Neuroblasts contain
Definition
Rods and Cones
Term
Outer Neuroblasts contain
Definition
Rods and Cones
Term
Innder Neuroblasts contain...
Definition
bipolar neurons
Term
Innermost neurons contain
Definition
ganglion cells (sprout axon to form optic nerve)
Term
5 Weeks Lens Development
Definition
** induced by sensory retina
pars iridea, lens vesicle, and cornea
Term
6-7 Weeks Lens development
Definition
- lens vesicle cells farthest from forming cornea start to lengthen
- elongated interior cells= Primary Lens Fibers
Non-elongated (near cornea)= lens epithelium (cuboidal)
Term
Germinative Mitotic Region of Lens gives rise to...
Definition
Secondary Lens Fibers (produce crystallines)
Term
3 Major Mesodermal Regions
Definition
1. Somite (Epimere)
2. Intermediate (Mesomere/Nephromere)
3. Lateral Plate/ Ventral (Hypomere)
Term
Components of Somites
Definition
1. Dermatome (dermis of dorsolateral wall)
2. Myotome- skeletal muscles
3. Sclerotome- axial skeleton and vertebrae
4. myocoel- embryonic
Term
Dermatome forms...
Definition
dermis of dorso-lateral body wall
Term
Myotome forms...
Definition
skeletal muscles of body
Term
sclerotome forms...
Definition
axial skeleton and vertebrae (not skull)
Term
myocoel forms
Definition
Nothing
Term
Derivatives of Intermediate Mesoderm
Definition
1. Nephric/ Excretory System
- Pronephros (adult kidney in primitive fish)
- Mesonephros (adult kid in amph.)
-Metanephros (adult kid in amniotes)
2. Parts of Genital System
- gonads and ducts
Term
Components of Lateral Plate/ Ventral Mesoderm
Definition
1. Somatic Mesoderm--- Tissues
2. Splanchic Mesoderm--- Structures (Heart/BV)
Term
Somatic mesoderm forms..
Definition
Tissues
Term
Splanchic Mesoderm forms
Definition
Structures (Heart and Blood Vessels)
Term
Limbs form from
Definition
Wolffian Ridge Region of Somatic Mesoderm
Term
Ectoderm of limb forms
Definition
apical ectodermal ridge.
Term
What determines the type of limb that develops?
Definition
Mesoderm
Term
Muscle of limb develops from
Definition
Somite myotome
Term
Skeleton/CT of Limb...
Definition
Lateral Plate Somatic Mesoderm
Term
BVs of Limb...
Definition
Lateral Plate Splanchnic Mesoderm
Term
Motor Nerves of Limb...
Definition
Spinal Cord Motor Nuerons (grow into limb)
Term
Sensory Neurons of Limb from...
Definition
Neural crest
Term
Schwann and pigmented cells of limb from...
Definition
Neural crest
Term
Syndactyly is...
Definition
webbed/ fused digits. (apoptosis did not occur)
Term
Coelom
Definition
cavity lined completely by mesoderm.
Term
# of teeth in adult human
Definition
32
Term
# of baby (milk teeth)
Definition
20
Term
Alveolus=
Definition
bony socket
Term
Alveolus is covered by
Definition
gingiva
Term
the gingiva consists of
Definition
1. Keratinized Stratified Sqaumous Epithelium
2. Lamina Propria of loose CT
Term
Dentin is produced by
Definition
Odontoblasts
Term
These extend into the dentin matrix from odontoblasts
Definition
Tome's fibers
Term
In the CROWN region of the tooth, the dentin is covered by
Definition
Enamel (calcified)
Term
Hardest substance in the body
Definition
enamel
Term
Enamel is formed by
Definition
ameloblasts (BEFORE it erupts from socket)
Term
In the ROOT region, dentin is covered by
Definition
Cementum (similar to bone, but no Haversian System)
Term
This connects the cementum to the bone
Definition
Peridontal Ligament by Sharpey's fibers
Term
Junctional Epithelium is..
Definition
where gingive meets tooth
Term
Epithelium is bound to tooth at
Definition
cuticle
Term
The cuticle is also called
Definition
Epithelial Attachment of Gottlieb (looks like a thickened basal lamina)
Term
Junctional Epithelium is attached to cuticle by
Definition
Hemidesmosomes
Term
Tooth Development begins
Definition
around weeks 5-6
Term
Vestibular Lamina
Definition
thickened epithelium of jaw surface.
Term
Labial Groove
Definition
invagination of vestibular lamina
-forms vestibule.
Term
Dental Papilla forms
Definition
Dentine and pulp of tooth
Term
Inner Enamel Epithelium will form
Definition
ameloblasts.
Term
Neural crest cells in dental papilla will form
Definition
odontoblasts
Term
Cervical loop will become
Definition
Hertwig's Epithelial Root Sheath
Term
At 6 Weeks, blood stem cells are found in
Definition
developing liver.
Term
From 8-16 weeks, blood stem cells are found...
Definition
in developing spleen, thymus, and lymph nodes.
Term
After 16 weeks, blood stem cells are found
Definition
in bone marrow.
Term
At 4 weeks, blood stem cells are found in
Definition
extraembryonic splanchnic mesododerm of YOLK SAC.
Term
Coeliac artery supplies
Definition
stomach
Term
Superior mesenteric artery supplies
Definition
small intestine
Term
Inferior mesenteric artery supplies
Definition
rest of intestine.
Term
Right and Left Umbilical Veins are found only
Definition
in amniotes.
Term
Before Basilar Artery is formed, vertebral arteries..
Definition
connect directly to Circle of willis.
Term
Right Dorsal Aortic Root anterior to arch #3 forms
Definition
rt. internal carotid.
Term
Right dorsal aortic root b/w #3 and 4 forms
Definition
nothing.
Term
Left dorsal aortic root anterior t #3 forms
Definition
lt. interior carotid.
Term
Lt. Dorsal aortic root b/w 3 and 4 forms
Definition
nothing
Term
Rt. Dorsal Aortic Root posterior to 4 forms
Definition
descending rt. subclavian.
Term
Lt. Dorsal Aortic root posterior to 4 forms
Definition
descending aorta.
Term
Right A.A. 1
Definition
small arteries in rt. mandible
Term
Lt. AA 1
Definition
small arteries in left mandible
Term
RT AA 2
Definition
small arteries in hyoid region.
Term
Left AA 2
Definition
small arteries in left hyoid region.
Term
RT AA 3
Definition
right internal carotid
Term
LT AA 3
Definition
Lt internal carotid.
Term
RT AA 4
Definition
RT Subclavian
Term
LT AA 4
Definition
Transverse Aorta
Term
RT AA 6
Definition
right pulmonary and ductus arteriousus
Term
LT AA 6
Definition
lt pulmonary and ductus arteriousus in embryo
Term
RT V. A. R anterior to #3
Definition
rt. external carotid
Term
LT VAR anterior to 3
Definition
lt external carotid
Term
RT VAR b.w 3 and 4
Definition
rt common carotid
Term
LT VAR b.w. 3 and 4
Definition
left common carotid
Term
RT VAR posterior to 4
Definition
pulmonary trunk
Term
LT VAR posterior to 4
Definition
systemic trunk
Term
Truncus arteriousus becomes
Definition
part of systemic and pulmonary trunk
Term
Bulbus arteriousus
Definition
bases of systemic and pulmonary trunks.
Term
Left subclavian is formed by
Definition
7th intersegmental artery
Term
Ductus arteriousus is formed to
Definition
bypass lungs in embryo
Term
Right and left vertebral arteries are connected to _______ and form from ______
Definition
subclavian, intersegmental
Term
Circle of Willis circles the
Definition
pituitary gland.
Term
Aorta forms from
Definition
lt and rt v and d aortic roots and 4th arch
Term
Hepatic Segment of IVC
Definition
right VV next to heart
Term
Mesenteric segment of IVC
Definition
Cephalic portion of Rt. Subcardinal
Term
Renal Segment of IVC
Definition
Anastomosis of RT and LT subcardinal veins and anastomosis of subcardinal anastomosis and rt. supracardinal vein.
Term
Post Renal Segment of IVC
Definition
rt. supracardinal vein
Term
Iliac anastomosis
Definition
Anastomosis of rt and lt posterior cardinal veins
Term
At 6 weeks, formation of IVC..
Definition
1. rt and left subcardinal veins fuse
2. iliac anastomosis
Term
At 7 weeks, form. of IVC
Definition
1. supracardinal veins form
2. right subcardinal fuses to rt. vitelline
3. sub/supracadinal anastomosis
Term
AT 8 weeks, formation of IVC
Definition
1. most posterior cardinal degenerate
2. hyperboly of rt. vv (hepatic segment)
3. anastomosis and hyperboly of subcardinal veins
Term
Azygous veins forms from
Definition
rt. posterior cardinal and supracardinal.
Term
rt. anterior cardinal forms _____ and the portion closest to c.c forms_____
Definition
rt. internal jugular and right brachiocephalic (innominate)
Term
Segmental branches of rt. anterior cardinal form
Definition
rt. subclavian
Term
lt anterior cardinal
Definition
lt. internal jugular and hightest intercostal vein
Term
segmental branches of lt. anterior cardinal form
Definition
left subclavian
Term
lt. cc form
Definition
oblique vein of heart (loses connection to sinus venosus)
Term
rt. cc
Definition
superior vena cava
Term
RT VV
Definition
1. (ant to liver)hepatic segment of IVC
2. small veins in liver
3. (post to liver)Hepatic portal vein and superior mesenteric artery
Term
LT VV
Definition
1. (ant to liver) degenerates
2. At liver, small veins and capillaries
3. post to liver, hepatic portal vein
Term
RT. UV
Definition
conection to S.V degenerates
2. at liver, small veins
3. post to liver, degenerates
Term
LT UV
Definition
1. connection to SV degenerates
2. at liver, small veins
3. post to liver, connects to ductus venosus in liver (supplies blood from placenta and mother)
Term
ductus venosus
Definition
connects L UV to IVC in order to shunt blood to Right Side of Heart
Term
Hepatic Portal Vein connects
Definition
small intestine to liver.
Term
4 pulmonary veins connect to ____ atrium by _____
Definition
left, 8-9 weeks.
Term
At birth, L UV becomes
Definition
Round Ligament of Liver
Term
Nasolacrimal Groove will form
Definition
lacrimal duct
Term
Upper Jaw forms from
Definition
Maxillary and nasomedial processes
Term
Lower jaw forms from
Definition
lateral and ventro-lateral portion of mandibular arches
Term
Tympanic Membrane
Definition
1. forms from hyomandibular cleft
2. ectoderm and endoderm
Term
Pinna
Definition
Tissue around outer ear
Term
Oronasal membrane
Definition
ectodermal lining of olfactory pit with endodermal lining of pharynx. (degenerates)
Term
V. A 1 forms
Definition
maxilla, mandible, malleus, and incus of middle ear

CN #5
Term
V. C #1
Definition
External Auditory Meatus
Term
V. P #1
Definition
Eustachian Tube and Middle Ear
Term
V. A #2
Definition
facial bones and cartilage, stapes of Middle Ear
CN #7
**"Opercular Flap" of cervical sinus in Embryo
Term
Visceral Cleft #2
Definition
Cervical Sinus of Embryo
Term
Visceral pouch #2
Definition
Palatine Tonsils
Term
V.A 3
Definition
neck bones, cn #9
Term
V.C 3
Definition
Cervical Sinus in Embryo
Term
V. P # 3
Definition
Inferior Parathyroid 3 and thymus 3
Term
VA 4
Definition
Laryngeal Cartilages, CN #10
Term
VC 4
Definition
Cervical Sinus of Embryo
Term
VP 4
Definition
Parathyroid, Thymus, Ultimobrachial bodies 4
Term
VA 6
Definition
hard to see in amniotes
Term
Pinna of ear
Definition
develops from 6 swellings (auricular hillocks) that border hyomandibular cleft
Term
Utricle forms
Definition
utriculus and semicircular canals
Term
Saccule forms
Definition
sacculus and cochlea
Term
Thyroglossal ducts breaks up during
Definition
2nd month.
Term
Thyroid secretes
Definition
colloid (thyroglobulin)
Term
Parathyroid secretes
Definition
parathyroid hormone (increases blood calcium)
Term
ultimobrachial bodies secrete
Definition
calcitonin (decrease blood calcium)
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