granulomatous large vessel vasculitis

aortic arch vessels

Asian women and children

absent upper extremity pulse

visual defects, stroke

granulomatous large vessel vasculitis involving superficial temporal and ophthalmic arteries, thrombi contain microabscesses

adults >50 years

temporal headache, jaw claudication, ipsilateral blindness

Increased ESR - sensitive

necrotizing medium-sized vessel vasculitis in renal, coronary, mesenteric arteries

middle-aged men

associated with HBsAg

focal vasculitis, aneurysms, vessels with chronic and acute inflammation, organ infarction

p-ANCA

necrotizing medium-sized vessel vasculitis involving coronary arteries

children <4 years

desquamating rash, swelling of hands and feet, cervical adenopathy, abnormal ECG

NO steroids

medium-sized vessel vasculitis with digital vessel thrombosis

male smokers 25-50

foot claudication, Raynaud's, ulceration, gangrene

necrotizing medium-sized and small vessel vasculitis involving URT, lung, renal vessels

childhood to middle age

necrotizing vasculitis, granulomas

saddle nose deformity

c-ANCA antibody

small vessel vasculitis

allergic rhinitis, asthma

p-ANCA

eosinophilia