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Vascular
lecture 11/10/11
59
Nursing
Undergraduate 1
11/10/2011

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Term
Arteries & arterioles three layers of arteries:
Definition
#1 intima inner layer >> thin smooth layer >> flow

#2 media middle >> smooth elastic tissue >> strength, dilate & constrict

#3 adventitia outer >> smooth muscle >> anchor

influenced by hormonal, chemical, and CNS systems
Term
Capillaries/intima
Definition
endothelial only layer >> a thin smooth layer >> flow
Term
The tunica intima (or just intima) is
Definition
the innermost layer of an artery or vein. It is made up of one layer of endothelial cells and is supported by an internal elastic lamina.
Term
The precapillary sphincter is
Definition
a band of smooth muscle that adjusts the blood flow into each capillary.
Term
A circulatory anastomosis is
Definition
a connection (an anastomosis) between two blood vessels, such as between arteries (arterio-arterial anastomosis), between veins (veno-venous anastomosis) or between an artery and a vein (arterio-venous anastomosis).
Term
three layers of veins,
similar to arteries but less defined:
Definition
#1 intima >> inner layer >> thin smooth layer >> flow
#2 media >> middle smooth elastic tissue >> strength dilate
& constrict
#3 adventitia >> outer smooth muscle >> anchor
Term
veins store what % of blood volume
Definition
75%
Term
Lymphatic vessels >>
Definition
network of thin walled vessels
refereed to as open ended but have openings via
minute flap valves that open into vessel allowing
large molecules through,
also have bicuspid valves in the lymph vessels, >>
nodes
Term
Lymphatic vessels Roles
Definition
Reabsorption of fluid rich in high molecular
weight as in proteins,
Major absorption of GI nutrients esp. Fats
Removal of large bacteria
Term
Lymphatic drainage
Definition
Approx. 120 cc per hour
drains into, can increase to 2000 cc / hour
Term
Formation of lymphatic fluid influenced by:• elevated capillary pressure
Definition
INCREASE
Term
Formation of lymphatic fluid influenced by:• decreased plasma colloid osmotic pressure
Definition
INCREASE
Term
Formation of lymphatic fluid influenced by:• increased interstitial pressure
Definition
DECREASE
Term
Formation of lymphatic fluid influenced by:• increased permeability of capillaries
Definition
INCREASE
Term
Interstitial reabsorption:
Definition
1/10th of interstitial fluid from the capillaries
9/10th absorbed by venous capillaries
Term
Movement of lymphatic fluid influenced by:
Definition
• lymphatic pump
contraction of muscles
movement
arterial pulsation
compression externally
• suction created in lymph vessels by fluid
movement
Term
The lymphatic pump is:
Definition
the flow of lymph from peripheral tissue to central lymph ducts, preventing backflow.
Term
Movement of lymphatic fluid limited by:
Definition
• interstitial pressure with edema
• edema and stretching of lymph vessel
separating valves
Term
Blood flow is a closed system with
vascular permeability compensated for
by
Definition
Lymphatic return
Term
Afterload
Definition
Pressure created by left ventricle on out flow of blood to the capillaries
Term
Precapillary sphincter
Definition
a band of smooth muscle that adjusts the blood flow into each capillary
Term
Venous Preload
Definition
the end volumetric pressure that stretches the right or left ventricle of the heart to its greatest geometric dimensions under variable physiologic demand.
Term
norepinephrine
Definition
it increases blood pressure by increasing vascular tone (tension of muscles) through α-adrenergic receptor one tenth - million of gram can cause
increased B/P 10-20 mmHgactivation. constricts arterioles
• constricts veins
• constricts renal arteries >> retention of fluid & salt
Term
epinephrine >> low dose
Definition
dilates
Term
epinephrine >> high dose
Definition
constricts
Term
Hypoxia, or hypoxiation, is
Definition
a pathological condition in which the body as a whole (generalized hypoxia) or a region of the body (tissue hypoxia) is deprived of adequate oxygen supply.
Term
pulmonary hypertension (PH)
Definition
is an increase in blood pressure in the pulmonary artery, pulmonary vein, or pulmonary capillaries, together known as the lung vasculature, leading to shortness of breath, dizziness, fainting, and other symptoms, all of which are exacerbated by exertion.
Term
An anastomosis is
Definition
a surgical connection between two structures. It usually means a connection that is created between tubular structures, such as blood vessels or loops of intestine.
Term
Idiopathic is
Definition
an adjective used primarily in medicine meaning arising spontaneously or from an obscure or unknown cause.
Term
ECCHYMOSIS. :
Definition
the escape of blood into the tissues from ruptured blood vessels. bruising
Term
Lymphadenopathy is
Definition
a term meaning "disease of the lymph nodes."
Term
Homans' sign is
Definition
a sign of deep vein thrombosis (DVT). A positive sign is present when there is pain in the calf or popliteal region with examiner's abrupt dorsiflexion of the patient's foot at the ankle while the knee is flexed to 90 degrees.[
Term
Streptokinase (SK),
Definition
a protein secreted by several species of streptococci can bind and activate human plasminogen. SK is used as an effective and inexpensive thrombolysis medication in some cases of myocardial infarction (heart attack)[2] and pulmonary embolism.
Term
AV Node
Definition
atrioventricular node is a part of the electrical control system of the heart that coordinates heart rate. It electrically connects atrial and ventricular chambers.
Term
Titrating
Definition
Continuously measure and adjust the balance
Term
ABI
Definition
Ankle Brachial Pressure Index the ratio of the blood pressure in the lower legs to the blood pressure in the arms.1.0 - 0.9 = normal
0.5 - 0.8 = moderate occlusion
less then 0.5 = severe occlusion
Term
Raynaud's phenomenon is
Definition
a vasospastic disorder causing discoloration of the fingers, toes, and occasionally other areas. This condition can also cause nails to become brittle with longitudinal ridges. the phenomenon is believed to be the result of vasospasms that decrease blood supply to the respective regions. Emotional stress and cold are classic triggers of the phenomenon.
Term
thrombocytopenia,
Definition
is a relative decrease of platelets in blood. A normal human platelet count ranges from 150000 to 450000
Term
SCD
Definition
sequential compression device
Term
PVD/DIAGNOSTIC MEASURES/-PT
Definition
Prothrombin Time Blood Test
Term
PVD/DIAGNOSTIC MEASURES/PTT
Definition
Partial Thromboplastin Time Blood Test
Term
PVD/DIAGNOSTIC MEASURES/INR
Definition
International Normalized Ratio
Term
PVD/DIAGNOSTIC MEASURES/Angiography
Definition
Angiography invasive evaluation of anatomy of vessel
Risks >> allergic reaction, chemical irritation, thrombus formation, embolus, dehydration / renal failure,
hemorrhage / infection, occlusion of vessel.
Term
Peripheral vascular Assessment/Position -
Definition
patient should be lying in the supine position and the bed or examination table should be flat. The patient's hands should remain at her sides with her head resting on a pillow.
Term
Peripheral vascular Assessment/Draping -
Definition
the legs should be exposed, the private groin and thigh covered. Drapes are usually placed between the legs.
Term
Peripheral vascular Assessment/On inspection the physician looks for signs of:
Definition
* trauma
* previous surgery (scars)
* muscle wasting/muscle asymmetry
* edema (swelling)
* erythema (redness)
* ulcers - arterial ulcers tend to be on the borders / sides of the foot, neuropathic ulcers on the plantar surface of the foot, venous ulcers tend on be on the medial aspect of the leg superior to the medial malleolus.
* hair - hair is absent in peripheral vascular disease (PVD)
* shiny skin - seen in PVD
* Haemosiderin deposits
* Lipodermatosclerosis
Term
Peripheral vascular examination/Palpation
Definition
* Temperature - cool suggest poor circulation, sides should be compared
* Pitting edema - should be tested for in dependent locations - dorsum of foot, if present then on the shins. If the patient has been in bed for a longer period of time one should check the sacrum.
* Capillary refill - should be less than 3 seconds.
Term
Peripheral vascular examination/Arterial pules to check
Definition
Femoral
Popliteal
Posterior tibial artery pulse
Dorsalis pedis artery
Term
Peripheral vascular examination/Auscultation for:
Definition
for femoral artery bruits
Term
Peripheral vascular examination/ Intermittent claudication >>
Definition
ischemic; cramping pain with execration, relief with rest, represents 50-75% occlusion also evaluated by distance ambulated prior to pain
Term
Peripheral vascular examination/ Buerger's Test (assessment of arterial sufficiency):
Definition
With the patient supine, note the colour of the feet soles. They should be pink. Then elevate both legs to 45 degrees for more than 1 minute. Observe the soles. If there is marked pallor (whiteness), ischemia should be suspected. Next check for rubor of dependency. Sit the patient upright and observe the feet. In normal patients, the feet quickly turn pink. If, more slowly, they turn red like a cooked lobster, suspect ischemia.
Term
Physical assessment of Peripheral Vascular System/Changes in color
Definition
Arterial pallor >> whiter or blanched
rubor >> reddish blue color with dependency

Both cyanosis>> bluish tint related to low SpO2
Term
Rubor:
Definition
Redness, one of the four classic signs of inflammation (together with dolor, calor, and tumor). From the Latin rubor, heat. See also: Dolor; Calor; Tumor.
Term
PVD/IMPLICATIONS:
Definition
Damaged Arteries
• Damaged Veins
• Blocked lymphatics
lead to infection, ulcerous tissue,
gangrene, loss of limb, decreased activity tolerance and
life style changes due to pain
Term
PVD/DIAGNOSIS
Definition
Lab Tests PT, PTT
INR; ABI Ankle - Brachial Index % of
flow to LE LEG / ARM
Doppler studies ( non invasive )
Angiography (invasive)
Term
Arterial vs Venous PVD/ PAIN
Definition
Venous Aching and cramping
Arterial Intermittent claudication >> ischemic
cramping pain with execration, relief with rest,
represents 50-75% occlusion also evaluated by
distance ambulated prior to pain
Term
Arterial PVD Tx:
Definition
development of collateral circulation with
exercise
Term
PVD/PA/ARTERIAL/COLOR:
Definition
pallor >> whiter or blanched
rubor >> reddish blue color with dependency
Term
PVD/PA/BOTH/COLOR:
Definition
cyanosis>> bluish tint related to low SpO2
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