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USMLE2 Pulm
Pulm
56
Medical
Professional
09/24/2012

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Cards

Term
Theophylline toxication
Definition
CNS stimulation (HA< insomnia), GI, cardiac tox (arrhythmia)
Term
RQ close to 1.0 indicates predominant oxication of what?
Definition
Carbohydrates
Term
AFP and B-HCG tumor markers
Definition
Nonseminomatous germ cell tumor
Term
If patient has pneumonia and laid on that side with happens?
Definition
Increase in right to left shunt.
Term
Exudative vs. transudative criteria
Definition
Pleural fluid protein/serum >0.5
Pleural fluid LDH/serum >0.6
Pleural LDH > 2/3 upper limit nl serum
Term
ARDS criteria
Definition
Acute onset of resp distress in the setting of predisposing condition
PaO2/FiO2 <200
bil infiltrates
normal PCWP
Term
New clubbing in patients with COPD
Definition
Lung Cancer
Term
Next step with undiagnosed pleural effusion?
Definition
Thorocentesis
Term
Recurrent pneumonia in same anatomic region of the lung suggest what? next step?
Definition
Bronchial obstruction. Get CT
Term
Legionella dx and treatment
Definition
Cough, fever >39, GI, confusion. Confirm with urine antigen testing. Treat with azithromycin or levofloxacin
Term
Chemo and radiation for Hidgkin's... watch for what down the road
Definition
Secondary malignancy
Term
Hope oxygen if SaO2
Definition
88
Term
Adult patient with recurrent bacterial infections
Definition
Humor immunity deficiciency. Quantitiate sermi Ig levels.
Term
What nueromuscular blocking agent can be used with liver and renal failure?
Definition
Atraciruium
Term
Reye's syndrome
Definition
Aspirin given to children. Fatty liver with encephalopathy. Diffuse mitochondrial injury. Eleveated serum aminotransfereases, elevated ammonia, PT prolongation, hypoglycemia, acidosis.

Treat with glucose, FFP, manitol
Term
Liver finding: balloon degeneration with polymorphic cellular infiltrates
Definition
Acute alcoholic hepatitis.
Term
Panlobular mononuclear infiltration with hepatic cell necrosis
Definition
Acute vital hepatitis. Bridging necrosis.
Term
Portal necrosis with piecemeal necrosis and or bridging fibrosis.
Definition
Chronic active hepatitis
Term
Alpha 1 antitrypsin deficiency stain
Definition
PAS+
Term
Acute cholecystitis
Definition
RUQ pain
Fever
Leukocytosis

IV antibiotics, NPO, analgesics
Term
Rotor syndrome
Definition
Defect hepatic storage of conjugated bilirubin. Leaking in plasma and urine.

No Tx necessary.

Conjugated bilirubin is water soluble, will appear in urine!
Term
Gilbert's syndrome
Definition
Unconjugated hyperbilirubinemia. Some icterus. non-specific complaints like malaise, fatigue, abdomnminal discomfort. Hemolysis, fasting, physical exertion, stress trigger.
Term
Acute cholangitis treatment no working. Next step?
Definition
ERCP
Term
Eye findings:
1) neovascularizatoin
2) dendritic ulcer
Definition
1) Chlamydia
2) Herpes simplex keratitis
Term
General anxiety disorder
Definition
Buspirone
Term
Dacryocystitis
Definition
Infection of the lacrimal sac. Sudden onset pain/redness of the medial canthal region. Give systemic antibiotics.
Term
Anorexia nervosa associated with what pregnancy complication
Definition
Small for gestational age. Also risk for miscarriage, hyperemesis, post partum depression.
Term
Most common cause painless hematuria in adults
Definition
1) Bladder mass.
Also presenting: renal cell carcinoma
Term
Most common cause of nephrotic syndrome in adults? Important complication?
Definition
Membranous glomerulonephritis. Important complication of renal vein thrombosis because antithrombin III is lost in the urine. Sudden onset abdominal pain, hematuria, fever.
Term
Renal complication to Hodgkin's lymphoma
Definition
Nephrotic syndrome: Minimal change disease
Term
Most common glomerulopathy associated with HIV?
Definition
Focal and segmental glomerulosclerosis.
Term
What diabetes drug should be stopped in patients with ARF, hepatic failure, or sepsis.
Definition
Metformin. Increases the chance of developing lactic acidosis.
Term
Lots of NSAID uses does what damage to kidney. Woman with HAs for years.
Definition
Analgesic nephropathy, papillary necrosis because of chronic tubulointerstitial damage. Takes several years.
Term
Muddy brown casts
RBC casts
WBC casts
Fatty casts
Broad/Waxy casts
Definition
ATN
Glomerulonephritis
Interstitial nephritis and prelo
Nephrotic syndrome
Chronic renal failure
Term
What to do if patient doesn't respond to susceptible antibiotics for pyelo?
Definition
Rule our underlying pathologie like obstruction or complications. Get US
Term
What can acyclovir do to the kidneys?
Definition
Cystalluria with renal tubular obstruction. LOTS of hydration.
Term
Vaccines for chronic liver disease
Definition
Tdap/Td, influenza, pneumo q5y, hepA, hepB
Term
Mixed cryoglobulinemia
Definition
Palpapbe purpura, proteinuria, hematuria. Nonspecific systemic: arthralgias, hepatosplenomegaly, hypocomplementermia. Underlying HCV
Term
Frequent stones. Hexagonal crystals. +cyanide nitroprusside test
Definition
Cystinuria, impaired amino acid transport. Hard and radioopaque.
Term
Most common nephrotic syndrome in children?

Most common in child with HepA?
Definition
Minimal change disease

Membranous glomerulonephritis
Term
Aminoglycosides (gentamycin, amikacin) cause what
Definition
Hard to use in renal dysfunction, must be monitored closely.
Term
Toxicity azathioprine
Definition
Dose-related diarrhea, leukopenia, hepatotoxicity
Term
Toxicity Mycophenolate
Definition
Marrow suppression
Term
Toxicity Cyclosprine
Definition
Nephrotoxic, HTN, neurotox, glu intol, infection, malig, gigival hypertrophy/hirsutism

Tacrolium causes similar w/o hirsutism or gums
Term
Most common cause of glomerulonephritis in adults
Definition
IgA nephropathy. Hematuria several days after URI. Normal complement.

(Post strep has decreased complement and takes 10+ days for pharyngitis)
Term
What requires emergency plasmapheresis?
Definition
Goodpasture's syndrome
Term
45 y/o HA, n/v, no fever. CT shows butterfly appearance with central necrosis.
Definition
Glioblastoma multiforme.
Term
Electrolyte abnormality with SAH
Definition
Hyponatremia due to SIADH
Term
Benign essential tremor treatment.
Definition
Beta blockers (can't use in asthma/copd, bradycardia)

Primidone (watch for porphyria - abd pain, confusion, HA, halluc, dizzy)
Term
Benztropine and trihexyphenidyl side effects?
Definition
Anticholiner. Red as beet, dry as a bone, hot as a hare, blind as a bat, mad as a hatter, full as a flask.
Term
Pronator drift
Definition
UMN sign
Term
RLS treatment
Definition
Dopamine agonists
Term
Wernicke's encephalopathy
Definition
Encephalopathy, oculomotor dysfunction, and gait ataxia.
Term
Glatiramer
Definition
Long term disease modifying treatment for MS
Term
Wallenberg syndrome
Definition
Lateral medulla lesion. Ipsilat horner's, loss pain/temp of face, weakness palate, pharynx, cords, cerebellar ataxia. Loss pain/temp contralateral body.
Term
Medial medullary syndrome
Definition
Contralateral spastic hemiplegia, contral vib/propioception loss, tongue deviation towards injured side.
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