Term
|
Definition
| Receptor -> PLC -> PIP2 -> IP3, DAG -> Ca++, PKC |
|
|
Term
|
Definition
| Receptor -> adenylyl cyclase -> cAMP -> PKA |
|
|
Term
|
Definition
| Receptor -| adenylyl cyclase, low cAMP, low PKA |
|
|
Term
G-protein class?
alpha-1
alpha-2
beta-1
beta-2 |
|
Definition
QISS (kiss)
alpha-1: q
alpha-2: i
beta-1: s
beta-2: s |
|
|
Term
|
Definition
vascular SM contraction
mydriasis (pupil dilation)
intestinal sphincter contraction
bladder sphincter contraction
Gq |
|
|
Term
|
Definition
decrease sympathetic outflow
decrease insulin release
-negative feedback-
Gi |
|
|
Term
|
Definition
increase HR
increase contractility
increase renin release
increase lipolysis
Gs |
|
|
Term
|
Definition
vasodilation
bronchodilation
increase HR
increase contractility
increase lipolysis
increase insulin release
decrease uterine tone
Gs |
|
|
Term
|
Definition
QIQ (kick)
M1: q
M2: i
M3: q |
|
|
Term
G-protein class?
D1
D2
H1
H2
V1
V2 |
|
Definition
SIQ SQS (sick sex)
D1: s
D2: i
H1: q
H2: s
V1: q
V2: s |
|
|
Term
|
Definition
|
|
Term
|
Definition
decrease HR
decrease atria contractility
Gi |
|
|
Term
|
Definition
| increase exocrine secretions (sweat, gastric acid) increase gut peristalsis increase bladder constriction bronchoconstriction miosis (pupil constriction) accommodation (ciliary muscle contraction) Gq |
|
|
Term
|
Definition
relax renal vascular SM
Gs |
|
|
Term
|
Definition
modulate transmitter release in CNS
Gi |
|
|
Term
|
Definition
increase nasal and bronchial mucus
bronchiole contraction
pruritus
pain
Gq |
|
|
Term
|
Definition
|
|
Term
|
Definition
vascular SM contraction
Gq |
|
|
Term
|
Definition
H2O reabsorption in collecting ducts
Gs |
|
|
