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USMLE Step 1 Buzz Words
Buzz words for step 1
75
Medical
Professional
04/17/2013

Additional Medical Flashcards

 


 

Cards

Term
HIV, heroin, interferon nephropathy
Definition
focal segmental glomerulosclerosis (nephrotic syndrome)
Term
"Spike and Dome" nephropathy w/ capillary/GBM thickening (a/w SLE)
Definition
Membranous nephropathy
Term
Foot process effacement (nephropathy)
Definition
Minimal change disease
Term
congo red stain = apple-green birefringence
Definition
amyloidosis
Term
"tram track" & subendothelial "humps" nephropathy, HBV & C3 associated
Definition
membranoproliferative glomerulonephritis (MPGN) [can be nephrotic too]
Term
nonenzymatic glycosylation (NEG) of GBM
Definition
diabetic glomerulonephropathy (nephrotic)
Term
Eosinophilic nodular glomerulosclerosis
Definition
(Kimmelstiel-wilson lesion) diabetic glomerulonephropathy (nephrotic)
Term
Hypercellular, neutrophils, "lumpy-bumpy" nephropathy, granular
Definition
acute poststreptococcal glomerulonephritis
Term
Crescent-moon shape w/ macrophages & monocytes; a/w Goodpasture & Wegener's
Definition
Rapidly progressive (crescentic) glomerulonephritis [RPGN]
Term
"wire-looping" capilaries w/ C3 deposits nephropathy (a/w SLE)
Definition
diffuse proliferative glomerulonephritis (DPGN)
Term
IgA (mesangium)nephropathy a/w Henoch-Schonlein
Definition
Berger's disease (IgA nephropathy)
Term
Glomerulonephritis w/ deafness, eye problems (cataracts)
Definition
Alport syndrome
Term
linear deposits on IF nephropathy
Definition
rapidly progressive glomerulonephritis (Goodpasture's)
Term
IgM, IgA, IgG, C3 deposit in mesangium (nephropathy)
Definition
Berger's disease (IgA nephropathy)
Term
Grey baby
Grey man
Red man
Definition
Chloramphenicol
Amiodarone
Vancomycin
Term
intranuclear Cowdry A bodies
Definition
HSV infx
Term
Owl's eye
Definition
CMV - in PMN or monocyte
Hodgkins - 2 owl eyes
Term
Downey Cells
Definition
EBV- T-cells, "foamy" cytoplasm
Term
a-synuclein
Definition
lewy body dementia
Term
Rash on palms and soles
Definition
Hand, foot, mouth dz (Coxsackievirus)
Rocky mt spotted fever
2ndary syphilis
meningococcus
Term
Koplik spots
Definition
buccal mucosa, red-blue-white
Measles (Rubeola)
Term
Negri bodies
Definition
Rabies, found in Purkinje cell of cerebellum
Term
Aerosolized mouse urine....
Definition
Hanta virus, LCMV, and Lassa virus
Leptospira interrogans bacteria
Term
signet-ring cells
Definition
gastric adenocarcinoma
ovary --> Krukenberg tumor
RBC --> trophozoite (malaria)
lobular carcinoma in situ (LCIS)
Term
strawberry tongue
Definition
Kawasaki
Scarlet fever
Term
Councilman bodies
Definition
viral hepatitis liver cells
Term
"Fried-egg" appearance
Definition
oligodendroglioma
testicular seminoma
koilocytes of HPV
Term
Schiller-Duval bodies
Definition
resemble primitive glomeruli
Yolk sac (endodermal sinus) tumor
Term
Reinke crystals
Definition
testicular non-germ cell tumors; Leydig cell
Term
testicular germ cell tumor w/ glandular/papillary convolutions
Definition
embryonal carcinoma
Term
testicular cancer w/ elevated AFP
Definition
yolk sac or embryonal carcinoma
Term
testicular cancer w/ elevated B-hCG
Definition
choriocarcinoma or embryonal cancer
Term
Cherry-red spot
Definition
Tay-sachs
Niemann-pick
Central retinal artery occlusion
Term
Lisch nodules
Definition
harmatomas of iris, neurofibromatosis
Term
Howell Jolly bodies
Definition
aspleenia, sickle cell
Term
Heinz bodies
Definition
G6PD
Term
Target cells
Definition
"HALT"
HbC dz
Asplenia
Liver disease
Thalassemia
Term
vaginal spindle shaped tumor cells that are desmin (+)
Definition
sarcoma botryoides (rhabdomyosarcoma variant)
Term
"Coffee bean" nuclei
Definition
Brenner tumor, ovarian epithelial cancer, histologically looks like bladder
Term
Ovarian cancer w/ fallopian tube-like epithelium
Definition
Serous cystadenoma, epithelial type cancer
Term
pseudomyxoma peritonei
Definition
mucinous cystadenocarcinoma, intraperitoneal accumulation of mucinous material from ovarian or appendiceal tumor
Term
triad: ovarian fibroma, ascities, hydrothorax
Definition
Meig's syndrome, ovarian fibroma
Term
Call-Exner bodies
Definition
small follicles w/ eosinophilic secretion, Granulosa cell tumors
Term
hemosiderinuria + thrombosis
Definition
PNH
Term
thyroid cells w/ optically clear nuclei
Definition
"orphan-annie" cells, papillary carcinoma of thyroid
Term
FMR1 gene
Definition
Fragile-X, CGG repeat, X-linked, encodes FMRP for brain/testes mRNA translation; mitral valve prolapse
Term
Quad-screen for Down's
Definition
decr. AFP/estriol
incr. B-hCG/inhibin A
Term
Down syndrome associations
Definition
duodenal atresia, ostium primum-type ASD, Alzheimers, increased ALL, U/S nuchal translucency.
95% meiotic nondisjunction of homologous chrs; 4% robertsonian transl; 1% mosaicism (no maternal component)
Term
Edward's syndrome (Trisomy 18) quad screen
Definition
decr. AFP/B-hCG/estriol
normal inhibin A
Term
Patau's syndrome (Tri 13) screening
Definition
decr. free B-hCG
decr. PAPP-A
increased nuchal translucency
Term
Edwards syndrome associations
Definition
rocker bottom feet, micrognathia, LOW-SET EARS, PROMINENT Occiput
Term
Patau's syndrome assocations
Definition
microcephaly, MIDLINE DEFECTS: holoProsencephaly, cleft liP/Palate, Polydactyly
Term
Turner Syndrome associations
Definition
streak ovary --> MCC of primary amenorrhea; cystic hygroma; preductal coarctation; horseshoe kidney; dysgerminoma (cancer); low estrogen --> incr. LH & FSH
Term
Klinefelter's associations
Definition
dygenesis of seminiferous tubules --> low inhibin --> incr. FSH
abnormal Leydig cells --> low test. --> high LH --> high estrogen
Term
Williams Syndrome
Definition
chr 7 microdeletion, including elastin gene; "elfin" face; hypercalcemia (hypersense to Vit.D); extremely friendly
Term
Cri-du-chat
Definition
congenital microdeletion of short arm Chr. 5; (46XY/XX, 5p-); high pitch cry
Term
22q11 deletion syndrome
Definition
CATCH-22
Cleft palate
Abnormal facies
Thymic aplasia (T-cell def.)
Cardiac defect
Hypocalcemia (parathy. aplasia)
22q11 micro deletion
90% of DiGeorge syndrome
Velocardiofacial syndrome
Term
"pseudopalasading" pleomorphic tumor cells
Definition
GBM, border central necrosis
Term
Rosenthal fibers
Definition
eosinophilic, corkscrew fibers, pilocytic astrocytoma
Term
Homer-wright rosettes
Definition
small blue cells, medulloblastoma
Term
perivascular pseudorosettes
Definition
ependymoma, rod shaped blepharoplasts
Term
Foamy cells
Definition
hemangioblastoma (childhood brain tumor)
von Hippel-Lindau syndrome
Term
Aschoff bodies
Definition
focal myocardial inflammation w/ multinucleate giant cells, rheumatic fever
Term
Mallory bodies
Definition
eosinophilic cytoplasmic globules in liver near nucleus (alcoholic liver dz)
Term
Curschmann spirals
Definition
desquamated epithelial casts in sputum (bronchial asthma)
Term
lens subluxation
Definition
Marfan's
homocystinuria
Term
CGG repeat
Definition
Fragile X syndrome
Term
GAA
Definition
Friedreich's ataxia
Term
CAG repeate
Definition
Huntington's disease
Term
CTG repeat
Definition
myotonic dystrophy
Term
berry aneurysms
Definition
ADPKD
Marfan's
Term
Cystic medial necrosis of aorta
Definition
Marfan's, leads to aortic incompetence and dissection
Term
Reed-sternberg cell
Definition
Hodgkin's disease; bilobe nuclei w/ increased cytoplasm and eosinophilic nuclei, filled with lymphocytes in background,
Term
"crinkled paper cytoplasm"
Definition
Gaucher's disease
Term
Pick bodies
Definition
spherical tau protein aggregates, frontotemporal dementia
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