Shared Flashcard Set

Details

USMLE Step 1
June 3, 2006
70
Medical
Graduate
06/03/2006

Additional Medical Flashcards

 


 

Cards

Term
Trousseau's Syndrome
Definition
migratory thrombophlebitis associated with pancreatic adenocarcinoma
Term
Courvoisier's sign
Definition
obstructive jaundice with palpable gallbladder associated with pancreatic adenocarcinoma
Term
lung surfactant
Definition
dipalmitoylphosphatidylcholine
Term
cardiologic defects associated with 22q11 syndome
Definition
truncus arteriosus and tetralogy of Fallot
Term
Cardiac defects associated with Down's syndrome
Definition
ASD, VSD
Term
Cardiac defects associated with congenital rubella
Definition
septal defects, PDA
Term
Cardiac defect associated with Turner's syndome
Definition
coarctation of the aorta
Term
Cardiac defect associated with Marfan's syndrome
Definition
aortic insufficiency/dissection
Term
Cardiac defect associated with a diabetic mother
Definition
transposition of the great vessels
Term
Cardiac defect associated with Kartagener's syndrome
Definition
dextrocardia/sinus inversus
Term
wide, fixing splitting of S2
Definition
ASD
Term
Krukenberg tumor
Definition
ovarian metastasis of a mucinous adenocarcinoma, usually from the stomach, presents bilaterally
Term
causes of dilated cardiomyopathy
Definition
alcohol, thamine deficiency (beriberi), prior myocarditis, hemochromatosis, idiopathic, coxsackie B virus, chronic cocaine use, Chagas' disease, doxorubicin toxicity, peripartum cardiomyopathy
Term
causes of restrictive cardiomyopathy
Definition
amyloidosis (seen in RA), sarcoidosis, postradiation fibrosis, endocardial fibroelastosis, endomyocardial fibrosis (Loeffler's)
Term
causes of hypertrophic cardiomyopathy
Definition
familial - mutation in sarcomere gene, autosomal dominant
Term
bcl-2
Definition
follicular and undifferentiated lymphomas
Term
c-myc
Definition
Burkitt's lymphoma
Term
erb-B2
Definition
breast, ovarian, gastric carcinomas
Term
l-myc
Definition
small cell lung carcinoma
Term
ret
Definition
MEN II and MEN III
Term
floor of the orbit
Definition
roof of the maxillary sinus
Term
communication of orbit and pterygopalantine fossa
Definition
inferior orbital fissure
Term
senile cardiac amyloidosis
Definition
transthyretin (prealbumin) mutation deposited as amyloid in organs in familial amyloid polyneuropathies - normally transports thyroxine and retinal
Term
AA amyloid
Definition
deposited in chronic inflammatory conditions
Term
AL amyloid
Definition
deposited in multiple myeloma and monoclonal B cell proliferations
Term
B2 amyloid
Definition
deposited in Alzheimer's
Term
B2 microglobulin amyloid
Definition
deposited in long-term hemodialysis
Term
von Recklinghausen's disease
Definition
Neurofibromatosis type I - cafe-au-lait spots, neural tumors, Lisch nodules (pigmented iris hamartomas), skeletal disorders (scoliosis), pheochromocytoma, increased tumor susceptibility
Term
Neurofibromatosis type I gene and chromosome
Definition
NF1 gene on chromosome 17
Term
Neurofibromatosis type II
Definition
bilateral acoustic neuroma, optic pathway gliomas, juvenile cataracts
Term
Neurofibromatosis type II gene and chromosome
Definition
NF2 gene on chromosome 22
Term
interosseus muscle innervation
Definition
ulnar nerve
Term
hand muscles innervated by the median nerve
Definition
abductor pollicis brevis, flexor pollicis brevis, opponens pollicis
Term
adductor pollicis muscle innervation
Definition
ulnar nerve
Term
BRCA1 chromosome
Definition
17q
Term
stomach cancer gene and chromosome
Definition
DCC on chromosome 18
Term
pancreatic cancer gene and chromosome
Definition
DPC gene on chromosome 18
Term
location of the dorsalis pedis artery
Definition
on the dorsum of the foot between the extensor hallucis longus and the extensor digitorum longus tendons
Term
polyhydramnios associations
Definition
duodenal and esophageal atresia
Term
Argyll Robertson pupils
Definition
tabes dorsalis (syphillis) - accommodation but no pupillary light reflex
Term
Ito cells
Definition
hepatic adipose cells found in space of Disse of liver, store vitamin A
Term
treatment for hypertrophic cardiomyopathy
Definition
B-blockers
Term
Pickwickian syndrome
Definition
pressure from a fatty neck causes intermittent airway obstruction
Term
idiopathic hypertrophic subaortic stenosis
Definition
occlusion of the aortic outlet causing dyspnea, angina, dizziness, congestive heart failure
Term
action of the upper fibers of the trapezius
Definition
elevation of the acromion
Term
1st degree heart block
Definition
prolongation of PR>200 ms, asymptomatic
Term
2nd degree heart block - Wenckebach
Definition
dropped P wave, prolongation of the PR, asymptomatic
Term
2nd degree heart block, type II
Definition
dropped beats without preceding PR prolongation, 2:1 block, pathologic - may progress to 3rd degree
Term
3rd degree (complete) heart block
Definition
atria and ventricles beat indpendently of each other, P waves bear no relation to QRS, atrial rate is faster than ventricular, treat with pacemaker
Term
mixed connective tissue disease
Definition
joint pain, myalgias, pleurisy, esophageal dysmotility, fatigue, skin disease, antibodies to ribonucleoprotein
Term
anti-centromere antibody
Definition
CREST
Term
anti-SCL-70
Definition
diffuse scleroderma
Term
anti-histone antibody
Definition
drug-induced lupus
Term
drugs that cause lupus-like syndrome
Definition
hydralazine, procainamide
Term
anti-dsDNA
Definition
SLE
Term
clubbing diseases
Definition
lung cancer (bronchogenic expect squamous cell), diaphragmatic neurilemmoma, mesothelioma, bronchiectasis, hepatic cirrhosis
Term
hypertrophic pulmonary osteoarthropathy
Definition
new subperiosteal bone associated with clubbing
Term
subcortical leukoencephalopathy
Definition
diffuse cortical loss due to hypertension, infarcts of frontal lobes with irregular loss of axons
Term
produces lytic and blastic bone lesions
Definition
breast cancer
Term
produces blastic bone lesions
Definition
prostate cancer
Term
produces lytic bone metastases
Definition
lung cancer
Term
most common metastases to bone
Definition
breast and prostate cancer
Term
drugs producing hemolysis in G6PD
Definition
sulfonamides (sulfa-tmp), nitrofurantoin, dapsone, primaquine, quinine
Term
infections of IV lines and prosthetic heart valves
Definition
Staph Epidermidis
Term
general sensation from posterior 1/3 of tongue, upper pharynx, eustachian tube
Definition
IX
Term
efferent to stylopharyngeus muscle
Definition
IX
Term
afferents from carotid body baroreceptors and carotid sinus chemoreceptors
Definition
IX
Term
HNPCC gene mutation
Definition
mismatch repair defect, microsatellite instability
Term
antimitochondrial antibody
Definition
primary biliary cirrhosis
Term
DNA gyrase action
Definition
introduces negative supercoils to stabilize an underwound DNA
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