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use and abuse of drugs
test 2
38
Pharmacology
Undergraduate 2
10/15/2012

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Term
cocaine history
Definition
grows in andes, 5000 BC, incas in peru used coca, coca wine (mariani) pope presented him a medal, local anesthesia
Term
cocaine forms
Definition
coca paste, cocaine hydrochloride-snorting, freebase-smoking, crack-street name for simple and stable prep for smoking, rock-another name for crack
Term
anti-drug act of 1986
Definition
supposedly targeted high level crack cocaine dealers and manufacturers, mine 5 yr sentence for selling 5 gr crack. max sentence of 1 yr for those with powder cocaine
Term
cocaine mechanism of action
Definition
blocks reuptake of dopamine, norepinephrine, and serotonin
Term
cocaine onset, absorption
Definition
chewing- releases slowly, snorting gets into system fast injected: high conc to brain, rapid and brief. metabolized by enzymes in blood and liver
Term
beneficial effects of cocaine
Definition
local anesthesia, lots of energy (not really a good thing.)
Term
cocaine acute and chronic toxicity, dependence potential reproductive effects
Definition
AT: convulsions, resp or cardiac arreest CT: using in a binge, can lead to paranoia, paranoid psychosis DP: can produce dependence, accounts for one of the largest proportions of admission for drug treatment in US, powerful reinforcer. RE: crack baby- increases risk of serious complications
Term
cocaine illicit supplies
Definition
available in US metropolitan areas, 1 kg 13-25 thou in US
Term
amphetamine history
Definition
chinese medicinal tea-ephedrine. stay awake-students. tested for narcolepsy treatment.
Term
amphetamine names
Definition
crystal meth, ice, speed, crank, methamphetamine most common
Term
difference between amphetamines
Definition
number of carbons on chain attached to benzene
Term
amphetamine mechanism of action
Definition
stimulate reuptake of NT's
Term
amphetamine 6 uses
Definition
depression, weight control, narcolepsy, hyperactive children, smart pills, athletics
Term
meprobmate-depressant
Definition
happy pills, muscle relaxant with CNS depressant analgesia anti anxiety, addicting-psychological and physical
Term
methaqualane-depressant
Definition
quaalude, sopor, ludes, sopors, 1960s, high abuse potential, sedative effects hypnotic properties
Term
anxiolytics
Definition
reduce anxiety
Term
benzodiazepines
Definition
diazepam (valium) alprazolan (xanax), lorazepam (ativan)
Term
benzodiazepine mechanisms
Definition
GABA system effects, anti-convulsants, muscle relaxants
Term
date rape drug
Definition
flunitrazepam (rohypnol)
Term
dalmane
Definition
rapid onset, long duration
Term
major cause of death... depressant combo
Definition
alcohol and valium
Term
barbiturates
Definition
chemical group of sedative-hypnotics
Term
benzodiazepines
Definition
chemical group of sedative hypnotics
Term
hypnotics
Definition
drugs used to induce sleep
Term
groupings of barbiturates
Definition
short: nembutal, seconal intermediate: laureate, amytal, butisol long: mebaral luminal
Term
nonbenzaodiazepine hypnotics
Definition
ambien and lunesta
Term
three major beneficial uses for benzodiazepines
Definition
anxiolytics (reduce anxiety), sleeping pills, anticonvulsants
Term
types of inhalants
Definition
paint and paint thinners, glue, nail polish remover, hair spray lighters fuel gas, whipped cream, correction fluid, paint removers, and a whole lot more!
Term
DSM-IV
Definition
diagnostic and statistical manual of mental disorders, provides criteria for diagnosis of mental disorders
Term
psychosis
Definition
a serious mental disorder involving loss of contact with reality
Term
schizophrenia
Definition
type of chronic psychosis
Term
depression
Definition
major type of mood disorder
Term
traditional anti-psychotics
Definition
chlorpromazine, thioridazine, haloperidol
Term
new generation anti-psychotics
Definition
clozapine, olanzapine, risperidone
Term
phenothiazines
Definition
group of drugs used to treat psychosis, first discovered while giving surgeries, calmed patients down, worked well on psychological patients
Term
4 primary classes of antidepressants
Definition
tricyclic, selective serotonin reuptake inhibitors (SSRIs) monnoamine oxidase inhibitors, atypical antidepressants
Term
trycyclic drugs
Definition
antidepressants, amitriptyline, miipramine, nortriptyline
Term
SSRIs
Definition
fluoxetine, paroextine, sertraline
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