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Urinary system
CH 18
28
Physiology
Undergraduate 3
07/09/2012

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Term
Kidneys-
Definition
form urine, primary blood (plasma) filter
Term
ureters
Definition
Transport urine from kidneys to bladder
Term
bladder
Definition
stores urine
Term
urethra
Definition
excrete urine from bladder to outside of body
Term
6 functions of urinary system
Definition
1. regulate plasma ionic composition
2. regulate plasma volume
3. regulate plasma osmolarity
4. regulate plasma pH
5. removes metabloic waste and foreign substances from plasma
6. hormone secretion
Term
Hormones secreted in urin
Definition
erythropoetin- increases red blood cell production
renin role in aldosterone production
Term
Kidneys receive % of cardiac output at rest
Definition
20%, large flow of blood, less than 1% of body weight, utilize 16% of ATP usage by body.
Term
Blood supply to kidneys via
Definition
renal arteries
Term
nephron=
Definition
microscopic functional unit of the kidney
1 million/ kidney
Term
Nephrons consists of
Definition
1. renal corpuscle
-glomerulus
-bowmans capsule
2. renal tubule- long tube divided into several specialized regions
Term
Glomerulus
Definition
found in renal corpuscle, twisted ball of blood capillaries.
plasma is filtered from blood and enters into tubule system.
Enters from afferent arterioles, leaves thru efferent arterioles which form peritubular capillaries.
Term
Bowmans capsule-
Definition
inflow end of renal tubule
Term
Renal tubule consists of
Definition
proximal convoluted tubule, loop of henle, distal convoluted tubule, collecting duct
Term
Basic process in forming urine
Definition
1. glomerular filtration
2. reabsorption
3. secretion
4. excretion
Term
first process of urine forming- glomerular filtration
Definition
plasma filtered from glomerulus into bowmans capsule
Term
2. reabsorption in forming urine
Definition
movement of substances from tubules back into blood
Term
3. urine forming step of secretion-
Definition
movement of substances from peritubular capillaries directly into tubules
Term
4. urine forming step of excretion
Definition
from tubules out of body
Term
filtrate of the kidneys is similar to
Definition
plasma, minus the plasma proteins
Term
% plasma passing through each kidney is filtered
Definition
20
Term
Glomerular Filtration (GFR)
Definition
rate of filtration = 125 mL/min or 180L/day
Term
Why is GFR regulated?
Definition
small increase in GFR= large increase in fluid filtered and excreted.
Term
Liters of urine excrited/ day
% fluid filtered and reabsorbed
Definition
1.5 L
99% is reabsorbed.
Term
GFR is dependent on
Definition
blood pressure (primary) and osmotic force of plasma (due to proteins)
Term
Increase Blood pressure-- filtration
Definition
increase
Term
increased blood pressure is do to dilating which is controled by
Definition
afferent arteriole, tubuloglomerular feedback
Term
tubuloglomerular feedback
Definition
decrease in kidney fluid- dilates afferent arterioles to increase BP and increase GFR (filters more fluid)
if increased fluid is in tubules, arterioles are constricted and decreased GFR (less fluid filtered)
Term
sympathetic control of GFR
Definition
increased stimulation causes constriction in afferent arterioles reducing blood flow which decreases fluid filtered (GFR) this conserves fluid in plasma to increase blood volume.
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