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Urinary System
Urinary System
79
Anatomy
Undergraduate 1
11/20/2011

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Term
Urinary system structures:
Definition
2 kidneys
2 ureters
urinary bladder
urethra
Term
Urinary system functions:
Definition
Regulates
blood pressure
electrolyte content of blood
pH balance of blood
tissue fluid
eliminates urine
Term
Kidneys
Definition
retroperitoneal (behind peritoneum)
below diaphragm
within rib cage
cushioned by adipose tissue
Covered by renal fascia (fibr. conn. Tissue)
hilus – indention on medial side
Term
INTERNAL KIDNEY STRUCTURE 3 areas:
Definition
Renal cortex
Renal medulla
Renal pelvis
Term
Renal cortex is the
Definition
Outer tissue layer made of renal corpuscles & convoluted tubules (parts of nephrons)
Term
Renal medulla is the
Definition
Inner tissue layer made of loops of Henle & collecting tubules (parts of nephron)
Term
Renal pelvis is the
Definition
Cavity formed by expansion of ureter within kidney at hilus
Term
Funnel-shaped extensions called
Definition
Calyces enclose papillae of renal pyramids
Term
*Urine flows from
Definition
Renal pyramids into calyces, to renal pelvis & into ureter
Term
Nephron is the
Definition
Structural & functional unit of kidney
Term
Each kidney contains
Definition
~1 million nephrons
Term
Nephrons form urine in association w/
Definition
Blood vessels
Term
Renal corpuscle is the
Definition
Glomerulus within Bowman’s capsule
Term
Glomerulus is
Definition
Capillary network
Term
Bowman’s capsule is expanded end of
Definition
Renal tubule that encloses glomerulus; inner layer (podocytes) creates spaces/pores (permeable); outer layer has no pores; space between contains renal filtrate
Term
Renal tubule continues from
Definition
Bowman’s capsule surrounded by peritubular capillaries
Term
Renal tubule contains
Definition
1)      proximal convoluted tubule
loop of Henle
distal convoluted tubules
collecting tubules
Term
Proximal convoluted tubule is
Definition
Renal cortex
Term
Loop of Henle is
Definition
Renal medulla
Term
Collecting tubules unite to form a
Definition
Papillary duct that empties into calyx of renal pelvis
Term
Blood vessels of kidney
Definition
Renal artery
Capillaries/Glomeruli
Renal vein
Term
Renal artery
Definition
receives blood from abdominal aorta
branches extensively w/in kidney into smaller branches
Term
Glomeruli are
Definition
Capillaries
Term
Renal vein
Definition
receives blood from glomeruli
takes blood to the inferior vena cava
Term
Blood vessel pathway:
Definition
Abdominal aorta – renal artery – smaller arteries in kidney – afferent arterioles in renal cortex – glomeruli – efferent arterioles – peritubular capillaries – veins in kidney – renal vein – inf. Vena cava
Term
FORMATION OF URINE - 3 major processes:
Definition
1.      Glomerular Filtration
Tubular Reabsorption
Tubular Secretion
Term
Glomerular filtration
Definition
•        Blood pressure forces plasma, dissolved substances & small proteins out of glomeruli & into Bowman’s capsule (renal filtrate)
Blood cells & larger proteins remain in blood
GFR (glomerular filtration rate) – amount of renal filtrate formed in 1 min.
Term
Tubular reabsorption
Definition
•        Takes place from renal tubules into peritubular capillaries
~ 99% filtrate reabsorbed back into blood; only 1% enters renal pelvis as urine
Most reabsorption occurs in proximal convoluted tubules whose cells have microvilli (> surface area)
Distal convolutes tubules & collecting tubules reabsorb h2o
Term
Mechanisms of Reabsorption:
Definition
•        Active transport – cells use ATP to move useful materials to blood (glucose, amino acids, vitamins & + ions)
Passive transport – many – ions
Osmosis – follows absorption of minerals, esp. Na+ ions
Pinocytosis – small proteins absorbed by cell membrane
Term
Tubular secretion
Definition
•        Changes composition of urine
Substances are actively secreted from blood into peritubular capillaries into filtrate in renal tubules
Waste products & metabolic products of meds. H+ ions may be secreted by tubule cells to maintain normal blood ph
Term
Hormones influencing water reabsorption:
Definition
1.      Aldosterone
Atrial natriuretic peptide (ANP)
Antidiuretic hormone (ADH)
Term
Aldosterone – stimulates
Definition
Reabsorption of Na ions
Term
Atrial natriuretic peptide (ANP) – decreases
Definition
Absorption of Na ions
Term
Antidiuretic hormone (ADH)
Definition
Distal convoluted tubules & collecting tubules able to reabsorb water from filtrate
Term
Other kidney functions
Definition
1.      Secretion of renin
Secretion of erythropoietin
Activation of vitamin D
Term
Secretion of renin
Definition
•        Secreted by walls of afferent arterioles when BP decreases
Initiates renin-angiotensin mechanism to raise BP
End product, angiotensin II, causes vasoconstriction & increase secretion of aldosterone
Term
Secretion of erythropoietin
Definition
•        Hormone secreted when blood O2 level decreases
Stimulates red bone marrow to increase rate of RBC production
Term
Activation of vitamin D
Definition
Converted to calcitrol (D2) which increases absorption of calcium & phosphate
Term
Elimination of urine
Definition
•        Ureters
Urinary bladder
Urethra
The Urination reflex
Term
Ureters
Definition
•        Smooth muscle
Each extends from hilus of kidney to lower, backside of urinary bladder
Smooth muscle of walls propel urine toward bladder in peristaltic waves
Lower ends compressed as bladder fills, preventing backflow
Term
Urinary bladder
Definition
•        Mucosa
Trigone
Detrusor muscle
Muscular sac
Reservoir for urine
Contracts to eliminate urine
Term
Urethra
Definition
Urethra carries urine from bladder to exterior
Term
Detrusor muscle
Definition
Smooth muscle layer of wall that forms a sphere; when contracts becomes smaller & volume diminishes; muscle fibers around urethral opening form internal urethral sphincter (involuntary)
Term
External urethral sphincter
Definition
•        Skeletal muscle on pelvic floor
under voluntary control
Term
The Urination reflex
Definition
•        Urination is aka: micturition or voiding
Stimulus is stretching of detrusor muscle
Can be prevented by voluntary contraction of external urethral sphincter (until too full)
Spinal cord reflex where voluntary control may be exerted
Term
Mucosa (transitional epithelium) allows
Definition
Expansion w/out tearing
Term
Trigone
Definition
Points of triangle are openings of ureters & urethra
Term
Characteristics of urine
Definition
Amount
Color
Specific gravity
pH
Constituents
Nitrogenous wastes
Term
Normal kidney urine output
Definition
1-2 L/24 hours
Term
Oliguria – from
Definition
Excess sweating or diarrhea, causing body to conserve water
Term
Polyuria – from
Definition
Excessive fluid intake, alcohol; increased urine formation & output
Term
Color
Definition
•        “Straw” or “amber” due to breakdown of bile
Concentrated urine is deeper yellow than dilute urine.
Freshly voided urine is clear.
Term
Specific gravity
Definition
Measure of dissolved materials in urine; indicator of kidney’s concentrating ability
Term
Urine ph
Definition
Normally between 4.6 & 8.0 (avg. 6.0); greatly influenced by diet
Term
Constituents
Definition
Salts are not considered true waste products but excess amts. Are eliminated in urine.
Term
Nitrogenous wastes
Definition
Urea (liver cells), creatinine (creatine phosphate metab.), uric acid (metab. Nucleic acids), and sm. Amts. Urobilin (from Hgb of old rbcs)
Term
Kidney related abnormalities
Definition
Floating kidney
Renal failure
Anemia
Kidney stones
UTI
Term
Floating kidney
Definition
One that has moved out of Nl. Position; ureter may become twisted or kinked
Term
Renal failure
Definition
Inability of kidneys to Fx properly; prerenal (in blood flow to kidneys), intrinsic (prob. W/kidneys) or postrenal (somewhere else in urinary tract)
Term
Hemodialysis
Definition
Artificial kidney machine filters blood
Term
Anemia
Definition
Consequence of renal failure; hemodialysis can’t reverse
Stoppage of erythropoietin production
Term
Kidney stones
Definition
Aka renal calculi
Concentrations of crystals of salts (calcium or uric acid) that most likely form in renal pelvis & cause intense pain & bleeding
May cause backup of urine & possible kidney damage
Term
What is Cystitis
Definition
Inflammation of urinary bladder
Term
What is Nephritis
Definition
Inflammation of kidneys
Term
UTI Bacteria usually from
Definition
Sexual contact
Term
a)      Which structure carries urine from bladder out of body?
hilus
nephron
trigone
ureter
urethra
Definition
Answer E
Term
a)      Outer tissue layer of kidney is called renal _____.
capsule
cortex
medulla
pelvis
pyramid
Definition
Answer B
Term
a)      The _____ is the capillary network of the nephron.
Bowman’s capsule
glomerulus
renal medulla
renal pelvis
renal pyramid
Definition
Answer B
Term
a)      Which structure carries urine from kidney to bladder?
hilus
nephron
trigone
ureter
urethra
Definition
Answer D
Term
a)      Inner tissue layer of kidney, containing loops of Henle and collecting tubules, called renal _____.
capsule
cortex
medulla
pelvis
pyramid
Definition
Answer C
Term
a)      The _____ encloses the capillary network of the nephron.
Bowman’s capsule
glomerulus
renal medulla
renal pelvis
renal pyramid
Definition
Answer A
Term
a)      The cavity formed by expansion of ureter within kidney, at hilus, is called renal _____.
capsule
cortex
medulla
pelvis
pyramid
Definition
Answer D
Term
a)      Which process involves blood pressure forcing plasma out of glomeruli into Bowman’s capsule within nephron?
glomerular filtration
tubular reabsorption
tubular secretion
Definition
Answer A
Term
a)      Which secretion of the kidneys influences blood pressure?
bilirubin
calcitrol
erythropoietin
renin
urea
Definition
Answer D
Term
a)      Which process involves incorporation of most of the filtrate back into the blood?
glomerular filtration
tubular reabsorption
tubular secretion
Definition
Answer B
Term
a)      Which secretion influences red blood cell production?
bilirubin
calcitrol
erythropoietin
renin
urea
Definition
Answer C
Term
a)      Which process changes the composition of urine, releasing waste products into the filtrate?
glomerular filtration
tubular reabsorption
tubular secretion
Definition
Answer C
Term
a)      Which characteristic of urine measures dissolved materials in urine and indicates kidney’s concentrating abilities?
amount
color
constituents
nitrogenous wastes
specific gravity
Definition
Answer E
Term
a)      Which of the following medical terms means “little production of urine?”
anuria
dysuria
minuria
oliguria
polyuria
Definition
Answer D
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