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Urinary System Pathology
For diagnostic medical sonography students. Only study term first, then definition. More of a Q&A than term/definition.
89
Medical
Undergraduate 4
01/31/2009

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Cards

Term
Three categories of renal cysts
Definition
1. acquired
2. inherited/congenital
3. developmental
Term
Simple and non-simple cysts belong to which renal cyst category?
Definition
acquired
Term
Cysts that are inflammatory, hemorrhagic, or septated belong to which: simple or non-simple?
Definition
non-simple
Term
Simple renal cysts are rare. True or False?
Definition
False
Term
Simple renal cysts are seen more commonly over what age?
Definition
50
Term
What part of the kidney are simple cysts usually located?
Definition
cortex
Term
What is a renal sinus cyst that does not connect with the collecting system called?
Definition
parapelvic cyst
Term
When scanning a parapelvic cyst, you should use Doppler to rule out what pathology with a similar appearance?
Definition
renal artery aneurysm
Term
Is a parapelvic cyst simple or non-simple?
Definition
simple
Term
A parapelvic cyst will always have smooth borders. True or False?
Definition
False. Parapelvic cysts can have irregular borders with a hydro-cauliflower appearance.
Term
A renal cyst that can have septations, low-level echoes, hemorrhage, inflammation, and/or infection.
Definition
non-simple cyst
Term
When echoes are seen within a renal cyst, the echoes should be seen in two views to rule out what?
Definition
artifact
Term
Patients with ___________ have increased risk of non-simple cysts and calcifations of these cysts.
Definition
polycystic disease
Term
It is possible for a non-simple cyst to be malignant. True or False.
Definition
True
Term
A kissing cyst is simple or non-simple?
Definition
non-simple
Term
Dysplastic cystic dilation of medullary and papillary portion of collecting tubules
Definition
medullary sponge kidney
Term
What are the two main complications of medullary sponge kidney?
Definition
1. stone formation
2. infections
Term
Medullary sponge kidney is seen mainly in what age group?
Definition
Children to young adults
Term
What area of the kidney appears abnormally echogenic in a patient with medullary sponge kidney?
Definition
The pyramids, due to reflections from microscopic cysts.
Term
Patients with medullary sponge kidney often have what other pathology?
Definition
Medullary nephrocalcinosis
Term
Inherited disorder of elastic connective tissue
Definition
Ehler-Danlos syndrome
Term
What pathology is associated with parathyroid adenoma, Caroli's disease, and Ehler-Danlos syndrome?
Definition
medullary sponge kidney
Term
Is medullary sponge kidney acquired or inherited?
Definition
acquired
Term
Autosomal-recessive disease in which fetus has large echogenic kidney due to multiple small cysts
Definition
infantile polycystic renal disease
Term
What causes the cysts in infantile polycystic disease?
Definition
abnormal proliferation and dilation of renal tubules
Term
Infantile polycystic renal disease is associated with what other pathology?
Definition
hepatic fibrosis
Term
Autosomal-dominant inherited cystic disease, bilateral but not fatal
Definition
adult polycystic kidney disease
Term
Cysts may be seen in what three other organs in patients with ADPKD?
Definition
1. liver
2. pancreas
3. spleen
Term
Patients with ADPKD have increased risk of what type of aneurysm?
Definition
berry
Term
Sonographic appearance of ADPKD
Definition
1.enlarged kidneys with multiple cysts
2. loss of renal shape
3. calcifications
4. no renal parenchyma in late stage
Term
True or False. ADPKD can lead to hypertension, then to renal failure.
Definition
true
Term
What makes Von Hippel-Lindau disease different from ADPKD?
Definition
1. bilateral cysts AND masses
2. increased chance of carcinoma
Term
Acquired cystic kidney disease develops in what type of patients?
Definition
renal failure patients receiving dialysis
Term
Patients with acquired cystic kidney disease have an increased risk of what type of cancer?
Definition
renal cell carcinoma
Term
Cysts in ACKD can appear in what two areas of the kidney?
Definition
1. cortex
2. medulla
Term
True or False. It is common for cysts to hemorrhage in ACKD.
Definition
true
Term
Sonographically, what makes tuberous sclerosis different from ADPKD?
Definition
multiple renal cysts AND angiolipomas
Term
Tuberous sclerosis is closely associated with what three conditions?
Definition
1. mental retardation
2. seizures
3. cutaneous lesions
Term
Autosomal dominant medullary cystic disease has an onset in what general age group?
Definition
Adult
Term
Autosomal recessive medullary cystic disease has an onset in what general age group?
Definition
juvenile
Term
Inherited cystic disease that rapidly progresses with uremia and death
Definition
autosomal dominant medullary cystic disease
Term
What disease is marked by salt loss, anemia, polyuria, and azotemia?
Definition
medullary cystic disease
Term
What is azotemia?
Definition
uremia toxic substance not removed by kidney
Term
What do endstage medullary cystic diseased kidneys look like?
Definition
1. small
2. echogenic
Term
Most common palpable abdominal mass in neonates
Definition
multicystic dysplastic kidney
Term
Most common childhood renal cystic disease
Definition
multicystic dysplastic kidney
Term
Is multicystic dysplastic kidney acquired, inherited, or developmental?
Definition
developmental
Term
Sonographically, the largest cyst in a patient with MDKD is located where?
Definition
periphery
Term
Sonographically: large kidneys with multiple cysts of different sizes in children and infants.
Definition
multicystic dysplastic kidney disease
Term
What is the only way that a baby can survive with a multicystic dysplastic kidney?
Definition
The baby must have one functioning kidney.
Term
What happens to a multicystic dysplastic kidney in an adult?
Definition
The diseased kidney becomes small and calcified.
Term
What is the appearance of the ureter of a multicystic dysplastic kidney?
Definition
A multicystic dysplastic kidney does not have a ureter.
Term
What developmental disease is associated with medullary sponge kidney, hyperparathyroidism, sarcoidosis, Cushing's syndrome, ACTH therapy, steroid use, malignant neoplasm, and Lesch-Nyhan syndrome?
Definition
medullary nephrocalcinosis
Term
Calcium in medullary pyramids, with or without shadowing.
Definition
medullary nephrocalcinosis
Term
What are the four malignant tumors of the kidney?
Definition
1. RCC 2. Wilm's Tumor 3. Transitional cell carcinoma 4. metastasis
Term
What are two other names for renal cell carcinoma?
Definition
1. RCC 2. hypernephroma
Term
Most common renal carcinoma
Definition
renal cell carcinoma
Term
70 year old man complains of flank pain, blood in the urine, and a palpable mass. Ultrasound shows a mass in the right kidney. Diagnosis?
Definition
RCC (hypernephroma)
Term
What malignancy of the kidney is associated with Von-Hippel Lindau disease?
Definition
renal cell carcinoma (RCC, hypernephroma)
Term
What is a common sonographic appearance to RCC?
Definition
hyperechoic rim or calcification to the mass
Term
What makes RCC look complex on an ultrasound?
Definition
necrosis and hemorrhage
Term
At what size does RCC look echogenic?
Definition
greater than 3 cm
Term
What three places should you check for extension of a hypernephroma?
Definition
1. renal veins 2. IVC 3. rt. atrium
Term
When using color and Doppler, what type of flow does RCC have?
Definition
highly vascular flow
Term
What are two things that help to diagnose RCC when it is isoechoic to the kidney?
Definition
1. hydronephrosis 2. lack of sinus in the mass
Term
What is the most common tumor of the renal collecting system?
Definition
transitional cell carcinoma
Term
pelvicalyectasis
Definition
dilation of the pelvis
Term
The main early symptom of TCC.
Definition
painless hematuria
Term
What echogenicities does TCC appear?
Definition
isoechoic to hypoechoic
Term
What type of patients have increased risk for developing TCC?
Definition
1. patients with vesicoureteral reflux 2.heavy smokers 3. exposure to carcinogens 4. treated with cyclophosphamide
Term
Where is metastasis common from (7 places)?
Definition
lymphoma, lungs, breast, choriocarcinoma, sarcomas, colon, and melanomas
Term
Where does renal lymphoma spread from?
Definition
adjacent lymph site
Term
What renal symptoms does non-Hodgkin's lymphoma produce?
Definition
none
Term
What is the most common renal tumor in children ages 1-8?
Definition
Wilm's tumor (nephroblastoma)
Term
What malignancy is associated with Beckwith Weidmann syndrome?
Definition
Wilm's Tumor (nephroblastoma)
Term
What does Wilm's tumor usually look like?
Definition
homogenous and echogenic
Term
What three places can Wilm's tumor metastasize to?
Definition
lung, brain, bone
Term
Wilm's tumor is commonly confused with what?
Definition
neuroblastoma of the adrenal glands
Term
What is the most common cortical mass?
Definition
adenoma
Term
Benign counterpart of RCC
Definition
adenoma
Term
A large adenoma more common in men
Definition
oncocytoma
Term
Sonographic marker of oncocytoma
Definition
stellate scarring, spoke wheel pattern (from hemorrhage and necrosis)
Term
Benign counterpart of Wilm's Tumor.
Definition
mesoblastic nephroma
Term
Most common solid kidney mass in neonate.
Definition
mesoblastic nephroma
Term
True or False. Calcifications are usually seen in mesoblastic nephroma.
Definition
False. Cystic degeneration is seen.
Term
Angiomyolipoma is common...
Definition
in women 40-60, in the right kidney
Term
How do you differentiate angiomyolipoma from sinus?
Definition
sinus is not well-defined
Term
In children with tuberous sclerosis, how does angiomyolipoma appear?
Definition
multiple, bilateral masses
Term
What is another name for angiomyolipoma?
Definition
renal harmatoma
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