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Unit 5 Review
Unit 5 Review
50
Pathology
Undergraduate 1
11/29/2010

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Cards

Term
What is the overall function of the kidneys?
Definition
Regulates the inner environment of the body by controlling the water-electrolyte balance and removing nitrogenous wastes.
Term
What are the functional units of the kidney?
Definition
Nephron
Term
What is the bulk of the energy used for by the kidney?
Definition
For active transport of sodium and co-transport of electrolytes and other substances.
Term
Describe justomedullary nephrons.
Definition
Nephrons that penetrate the entire length of the medulla.
Term
What all is absorbed in the proximal tube?
Definition
Water,electrolytes, glucose, and amino acids.
Term
The anti-diuretic hormone (ADH) acts on what structure(s) in the kidney?
Definition
Distal and collecting tubules.
Term
What usually causes kidney damage resulting from urinary tract obstruction?
Definition
Back pressure and ischemia.
Term
What is the most common type of kidney stone in people with urinary tract infections?
Definition
Magnesium ammonium phosphate (or struvite) stones
Term
Why is Aspirin not recommended for pain relief in people with gouty arthritis?
Definition
It decreases the secretion of uric acid into the renal tubules.
Term
How is cranberry or blueberry juice thought to control and prevent UTIs?
Definition
Reduction in bacterial adhesions to the epithelium of UT.
Term
Describe glomerulonephritis.
Definition
Inflammation involving the glomerular structures that can lead to kidney failure. Some known causes include bacterial infections and immune diseases.
Term
What does glomerulonephritis result from?
Definition
An immune response
Term
Describe acute proliferative glomerulonepphritis.
Definition
Increase in cellular components of the glomerulus, edema, oliguria, proteinuria, and hematuria.
Term
What are the endocrine functions of the kidney?
Definition
Activation of vitamin D and production of erythropoietin.
Term
What is a substance normally found in urine that closely reflects the glomerular filtration rate (GFR)?
Definition
Creatinine
Term
Describe the Urine Specific Gravity test.
Definition
It assesses the ability of the kidneys to concentrate urine.
Term
What does Aldosterone increase the re-absorption of and what does anti-diuretic hormone (ADH) increase the reabsorption of?
Definition
Aldosterone increases the re-absorption of Na, and ADH increases water absorption.
Term
What type of renal response is given for people who eat high-protein meals or have high glucose levels in their blood?
Definition
Increase in renal blood flow and GFR.
Term
What is the most common complication with urinary tract obstruction?
Definition
Infection
Term
What is the most common inherited disease that affects the kidneys?
Definition
Polycystic kidney disease is the most commonly inherited kidney disease.
Term
What is a characteristic sign of polycystic kidney disease?
Definition
Enlarged kidneys
Term
What blood test is used to detect the GFR and renal funtion?
Definition
Creatinine in the blood.
Term
What are the effects of kidney agenesis or hypoplasia if it affects one kidney in the body?
Definition
Few to none
Term
Describe the effects of cystic disease on the kidney.
Definition
Tubular dilation (caused by weakened tubule structures), tubular obstructions (that increase intratubular pressure), and a change in the basement membrane of the renal tubules.
Term
What prevention measure can be used to prevent all types of kidney stones?
Definition
Increase fluid intake.
Term
Which population is lease susceptible to urinary tract infections?
Definition
Adolescent boys
Term
What is the most common cause of nosocomial urinary tract infections?
Definition
Catheters (nosocomiar-hospital origination)
Term
What are the symptoms of lower urinary tract infections (UTIs)?
Definition
Enuresis, dysuria, suprapubic discomfort, frequency.
Term
Edema that develops in people with glomerulonephritis and nephrotic syndrome indicate what?
Definition
Loss of plasma proteins.
Term
What is the location and the function of the juxtaglomerular apparatus?
Definition
The justaglomerular apparatus is at the point of contact between the distal convoluted tubule and the afferent and efferent arterioles. Regulates the functions of each nephron.
Term
The most frequent causes of intrarenal failure are:
Definition
Acute tubular necrosis, hypoxia-related renal failure, and exposure to nephrotoxic poisonous substances
Term
What can cause the interruption of renal blood flow?
Definition
Trauma and shock
Term
Describe acute tubular necrosis.
Definition
Destructive changes in tubular epithelium. One of the most common causes of acute renal failure.
Term
What causes the majority of acute tubular necrosis?
Definition
Often caused by ischemia or nephrotoxic agents.
Term
End-stage renal disease is characterized by what alterations?
Definition
Endocrine functions of the kidney, alterations in filtration and re-absorption.
Term
What is an early sign of renal failure?
Definition
An increase of nitrogenous wastes in the blood
Term
What is nocturia and its symptoms?
Definition
Urination at night; loss of ability to concentrate urine
Term
What is the moving force of filtration?
Definition
The blood pressure in the glomerulus.
Term
What causes anemia?
Definition
Impaired synthesis of erythropoietin and effects or uremia.
Term
What can cause the development of hypertension in a person with renal failure?
Definition
Increased intravascular fluid, and the rennin-angiontensin mechanism.
Term
Failure to empty the urine from the bladder or flaccid dysfunction is caused by what conditions.
Definition
Interrupted afferent and efferent innervations of the bladder.
Term
What is the most common cause of flaccid bladder dysfunction?
Definition
Spinal cord injury
Term
What is the most common sign of bladder cancer.
Definition
Painless hematurea.
Term
What structure distal to the base of the bladder is responsible for continence?
Definition
The external sphincter.
Term
What are the symptoms of early stages of obstruction to urine outflow from the bladder?
Definition
Frequency and urgency
Term
What are the main levels of neurological control of bladder function?
Definition
Not hypothalamus (spinal reflex ctr., cerebral cortex, pontine micturition)
Term
The reflex control of bladder emptying occurs at what level?
Definition
the sacral portion of the spinal cord.
Term
What is the most common cause of urinary obstruction in males?
Definition
Benign prostatic hyperplasia
Term
What can cause the failure to store urine?
Definition
Reflex bladder spasm, decrease of bladder volume, interference w/ motor innervation.
Term
What can happen as a result of a stroke that affects the cortex or corticospinal pyramidal tract?
Definition
The ability to preceive bladder filling is lost; voiding occurs suddenly and w/o warning.
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