Term
|
Definition
antimuscarinic effects, sedation
popular antihistamine |
|
|
Term
|
Definition
| moderately sedating, OTC "sleep aid" |
|
|
Term
|
Definition
|
|
Term
|
Definition
antimuscarinic effects, marked sedation
antiemetic |
|
|
Term
|
Definition
less sedating, cheap
component of cold medications |
|
|
Term
|
Definition
newest, fewer central effects
cross BBB poorly, longer duration of action, more $$$ |
|
|
Term
|
Definition
2nd gen antihistamine
effective - intranasal spray for allergic rhinitis
opthalmic solution for allergic conjunctivitis
prodrug - p450 converts to active metabolite |
|
|
Term
|
Definition
compete at H2 receptor on basolateral membrane of parietal cells
blocks gastric acid secretion in response to all stimuli but reduction in nocturnal acid secretion much more pronounced than meal-stimulated acid secretion |
|
|
Term
|
Definition
uticaria, diarrhea of carcinoid
adverse effects: antimuscarinic, sedation |
|
|
Term
|
Definition
| antihypertensive, antagonizes platelet aggregation |
|
|
Term
|
Definition
| nausea and vomiting associated with radiotherapy and chemo |
|
|
Term
|
Definition
| action on DA receptor supresses prl secretion from pituitary |
|
|
Term
|
Definition
Migraine
5-HT1,2 receptor agonist
N+V and culmilative prolonged vasoconstriction |
|
|
Term
|
Definition
| migraine prophylaxis, HT-1/2 agonist, GI disturbances, occasional hallucinations, inflammatory fibrosis |
|
|
Term
|
Definition
acute migraines
5-HT1b,d
cerebral vasoconstriction, acts on receptors of trigem to inhibit peptides from vasodilating
receptors on brainstem prevent trigem from activating |
|
|
Term
|
Definition
|
|
