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Unit 1 B Drugs
GI Drugs
62
Pharmacology
Not Applicable
09/19/2011

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Term
appetite suppressants
Definition
steroids, megace, marinol
Term
Marinol
Definition
Appetite suppressant - to treat obesity
pill form of marijuana
Term
fluconazole
Definition
Diflucan---Antifungal-
Used to treat stomatitis
Term
maalox-
Definition
antacid- FOR GERD
STAGGER c meds- decreases absorption and effectiveness of other medicines
Term
Purpose of antacids
Definition
relieve mild or moderate symptoms by neutralizing stomach acid
Term
Baking Soda === sodium bicarbonate ===antacid for GERD
Definition
antacid- for GERD
DANGEROUS-- Na = CHF, edema, bicard= alkalosis = renal failure
exacerbates fluid retention
delays patients from seeking help
Term
Aluminum based antacids
Definition
amphojel, alucap, dialume
do not use if have HTN or heart failure
DECREASES effects of coumadin and digoxin
Term
famotidine
Definition
Pepcid--H2 blocker
take at hour of sleep for GERD
Term
ranitidine
Definition
Zantac- H2 blocker
take at hour of sleep for GERD
Term
omeprazole
Definition
prilosec--- PPI
Don't crush
interferes with absorption of other drugs
Term
lansoprazole
Definition
prevacid-- PPI
don't crush
interfers with absorption of other drugs
Term
sucralfate
Definition
Carafate---Anti-ulcer agent
Don't crush or chew--shake suspension well
Term
metoclopramide
Definition
Reglan--- Promotility agent - antiemetic
30 minutes before meals
Extrapyramidal SE = tremor, slurred speech, anxiety, paranoia
Term
cimetidine
Definition
Tagamet-- H2 blocker
take at HS
Term
ondansetron
Definition
Zofran- Serotonin receptore antagonist
ANTI-EMETIC
Hepatotoxic
Term
Compazine
Definition
Dopamin antagonist- antiemetic
Term
hydrOXYzine
Definition
Vistaril- Antihistamine
to treat nausea associated with inner ear problems
Term
lorazepam
Definition
Ativan--- benzodiazepines--antiemetic
Term
dexamethasone
Definition
Decadron-- corticosteroid- antiemetic
Term
metronidazole
Definition
Flagyl-- Anti-protozoal anti-infective, antiulcer. FOR CHRONIC GASTRITIS
Do not break, crush, or chew
Neurotoxic
Term
clarithromycin
Definition
Biaxin- Macrolide- anti-infective, antiulcer FOR CHRONIC GASTRITIS
admin with food- do not crush, break or chew,
Term
bismuth subslicylate
Definition
Pepto-Bismol -- antidiarrheal, antiulcer, absorbents-- FOR CHRONIC GASTRITIS & PUD
Helps eradicate H. Pylori
increases mucosal bicard and prostagladin to heal ulcers
Term
lamivudine
Definition
Epivir---antiretrovirals-- NRTI
Used to treat Hep B
Term
ribavirin
Definition
Virazole- antiviral
Used to tx Hep C
Term
spironolactone
Definition
Aldactone = K sparing diuretic-
Used in CIRRHOSIS to decrease fluid retention
Term
furosemide
Definition
Lasix = loop diuretic
Used in CIRRHOSIS to decrease fluid retention
Term
Lactulose
Definition
Osmotic laxative-
Used in CIRRHOSIS to bind with ammonia and excrete it in stool
Term
neomycin
Definition
aminoglycoside- Antibiotics used to decrease ammonia levels in CIRRHOSIS
Term
Vitamin K
Definition
improves clotting times in CIRRHOSIS
Antidote for Coumadin and Digoxin
Term
Beta Blockers to tx CIRRHOSIS
Definition
decrease BP related to portal hypertension from sclerosis liver
Term
Absorbants & Protectants for Diarrhea
Definition
charcoal, kaopectate, pepto-bismol
Term
opium drugs for diarrhea
Definition
paregoric, opium tincture
Term
opium derivatives for diarrhea
Definition
lomotil, imodium (watch for synergy if on other narcotics= can paralyze GI tract)
Term
anticholinergics
Definition
Atropine, belladona, Probanthine
(slows GI tract down by inhibiting actelycholine the major neurotransmitter of parasympathetic nervous system)
Term
Bulk forming laxatives
Definition
psyllium, methycellulose, polycarbophil- mixi in full glass cool liquid. works in 1-3 days
Term
Wetting/surfactant laxative
Definition
docusate-provide ample fluids. AVOID other meds for 1 hour. DO NOT crush or open caplets
Term
Osmotic & Saline Laxatives
Definition
mag. citrate, MOM, lactulose, and polyethylene glycol--Don't give if fluid deficit or NA restrictions. Take with full glass of liquids
Term
Irritant/Stimulus
Definition
bisacodyl, senna, castor oil--take on empty stomach and DO NOT crush
Term
tegaserod mesylate
Definition
zelnorm = used to tx constipation in women with IBS
Term
lubiprostone
Definition
Amitiza-used to tx constipation in women with IBS
Term
dicyclomine
Definition
Antispas- used for tx of diarrhea in pt with IBS
Term
hyoscyamin
Definition
Anaspaz- used to tx diarrhea in pt with IBS
Term
imipenem
Definition
Primaxim- broad spectrum abx for PERITONITIS
Term
merpenem
Definition
Merrem- broad spectrum abx used to tx PERITONITIS
Term
contaminated food and water
Definition
Travelers Diarrhea
Term
undercooked beef, unpasteurized milk, apple juice, or fecal-oral (cattle)
Definition
Hemorrhagic E. Coli
Term
foods left @ room temperature (dairy, meats, fish)
Definition
Food Poisioning (staphylococcal)
Term
fecal-oral, vectors and objects
Definition
shigella (dysentery) lock of hair in journal!
Term
oral-fecal contamination
Definition
cholera
Term
contagious fecal-oral contact. contaminations in institutions
Definition
norovirus
Term
abx use
Definition
c. diff
Term
raw or improperly cooked meats, poulty, eggs, and dairy
Definition
salmonella
Term
raw or improperly cooked meats, poulty, eggs, and dairy
Definition
salmonella
Term
raw or improperly cooked meats, poulty, eggs, and dairy
Definition
salmonella
Term
pyrantel pamoate
Definition
antiminth- tx of helminthic infections
Term
mebendazole
Definition
(Vermox)- tx of helminthic infection
Term
albendazole
Definition
albenza- tx of helminthic infection
Term
sulfasalazsine
Definition
Azulfidine- potent anti-inflammatory (sulfa and 5-ASA)
Term
sulfasalazsine
Definition
Azulfidine- potent anti-inflammatory (sulfa and 5-ASA) for ULCERATIVE COLITIS and CROHN's
Term
balsalazide
Definition
Colazal- potent anti-inflammatory for UC
Term
immunsuppresive drugs for CROHNS
Definition
azathiprine, mercaptopurine, methotrexate
Term
broad spectrum abx to tx DIVERTICULITIS
Definition
metronidazole (flagyl) and ciprofloxacin (cipro)
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