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Details Title UMDNJ-SOM pharm autonomics exam 1 Description ohhhh vogel Total Cards 60 Subject Pharmacology Created 08/23/2010

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Cards

Term Ach	Definition +, short direct acting, PSmimetic
Term bethanechol	Definition +, long direct acting PSmimetic
Term methacholine	Definition +, long direct acting PSmimetic
Term carbachol	Definition +, long direct acting PSmimetic
Term pilocarpine	Definition natural, direct acting, PSmimetic
Term muscarine	Definition + natural, direct acting, PSmimetic
Term edrophonium	Definition +, reversible short acting, anticholinesterase
Term physostimine	Definition reversible, natural, longer acting, anticholinesterase
Term neostigmine	Definition +, reversible longer acting, anticholinesterase
Term pyridostigmine	Definition +, reversible longer acting, anticholinesterase
Term DFP, isofluorophate, organophosphate	Definition irreversible anticholinesterase
Term nicotine	Definition in small doses, ganglionic agonist. in large doses, ganglionic antagonist
Term trimethaprin	Definition ganglionic antagonist
Term atropine	Definition natural competitive M blocker
Term scopolamine	Definition natural competitive M blocker
Term ipratopium	Definition synthetic competive M blocker (some ganglionic blocking activity)
Term tiotropium	Definition +, synthetic competive M blocker (some ganglionic blocking activity)
Term propantheline	Definition +, synthetic competive M blocker (some ganglionic blocking activity)
Term tropicamide	Definition synthetic competive M blocker (some ganglionic blocking activity)
Term cyclopentolate	Definition synthetic competive M blocker (some ganglionic blocking activity)
Term norepinephrine	Definition exogenous, catecholamine, direct on alpha's, some beta1
Term epinephrine	Definition exogenous, catecholamine, direct on all A's and B's
Term isoproterenol	Definition catecholamine, direct on B's
Term dopamine	Definition exogenous, catecholamine, direct on all A's and B's and DA (dilate renal vessels)
Term dobutamine	Definition catecholamine- direct on B1
Term phenylepineprhine	Definition non-cat, direct on A1
Term tetrahydrozoline	Definition non-cat, direct on A1
Term naphazoline	Definition non-cat, direct on A1
Term oxymetazoline	Definition non-cat, direct on A1
Term clonidine	Definition non-cat, direct on A2
Term ritodrine	Definition non-cat, direct B2> B1
Term metaproterenol	Definition non-cat, direct B2> B1
Term albuterol	Definition non-cat, direct B2> B1
Term salbutamol	Definition non-cat, direct B2> B1
Term salmeterol	Definition non-cat, direct B2> B1
Term formoterol	Definition non-cat, direct B2> B1
Term terbutaline	Definition non-cat, direct B2> B1
Term ephedrine	Definition indirect, increased NE release, easily cross BBB
Term pseudoephedrine	Definition indirect, increased NE release
Term amphetamine	Definition indirect, increased NE release, easily cross BBB
Term cocaine	Definition indirect, decreased uptake of NE
Term prazosin	Definition block A1
Term tamsulosin	Definition block A1
Term doxazosin	Definition block A1
Term phentolamine	Definition blocks all A, competitive, short
Term phenoxybenzamine	Definition blocks all A's, irreversible
Term propranolol	Definition blocks both B's
Term timolol	Definition blocks both B's
Term nadolol	Definition blocks both B's (least lipophilic)
Term metoprolol	Definition cardioselective, blocks B1, (B2 at high dose)
Term acebutolol	Definition cardioselective, blocks B1, (B2 at high dose)
Term atenolol	Definition cardioselective, blocks B1, (B2 at high dose)
Term labetalol	Definition vasodilator- A and B blocker
Term pindolol	Definition partial B agonist (acitivty depends on state)
Term carteolol	Definition partial B agonist, activity depends on state
Term d-tubocurarine	Definition natural, competitive, non depol NMJ blocker (20 minutes), reversed by anticholinesterase
Term mivacuronium	Definition competive, non depol NMJ blocker (hour), reversed by anticholinesterase
Term pancuronium	Definition competive, non depol NMJ blocker (hour), reversed by anticholinesterase
Term succinylcholine	Definition depolarizing, NMJ blocker anticholinesterase doesn’t help (minutes)
Term botulinus toxin	Definition Ach release inhibitor, irreversible paralysis, sx's releived after new ones made

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