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Ultrasound (Fall)
GB - Abnormal
94
Medical
Professional
10/18/2009

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Cards

Term
What is calcification of the gb wall called?
Definition
porcelain gb
Term
Porcelain gb occurs in association with?
Definition
gallstones disease and may represent some form of chronic cholecystits
Term
What determines the sonographic appearance for porcelain gb? 
Definition
the degree and pattern of calcification
Term
What is seen sonographically when the entire gb wall is thickly calcified?
Definition
a hyperechoic semilunar line with dense posterior acoustic shadowing is noted
Term
what is seen sonographacially when there is a mild calcification on the gb?
Definition
appears as an echogenic line with variable degrees of posterior acoustic shadowing
Term
how does the lumen of porcelain gb look?
Definition
the luminal contents may be visible. interrupted clumps of calcium appear as echogenic foci with posterior shadowing
Term
Why is the WES sign absent in a porcelain gb?
Definition
because the calcifications occur in the wall
Term
What is the benign condition affecting the gb wall?
Definition
adenomyomatosis
Term
adenomyomatosis is aka
Definition
rokitansky-aschoff sinuses
Term
what is seen in adenomyomatosis?
Definition
diverticula within the gb wall accumulate stones or sludge within them
Term
adenomyomatosis can be ______ or _______
Definition
focal or diffuse
Term
What is the common appearance of adenomyomatosis?
Definition

tiny echogenic foci in the gb wall that creat comet-tail arifacts

echogenic foci with ringdown or with twinkling artifact on doppler exams 

Term
The finding of absence of the echogenic foci or twinkling artifact or the presence of internal vascularity should promot further investigation to _____________
Definition
neoplasm
Term
What are the different types of Polypoid masses?
Definition

Cholesterol polyps

inflammatory polyps

adenoma

focal adenomyomatosis

gb adenocarcinoma

metastases (especially melanoma)

Term
Why is the differentiation of benign and malignant polys important?
Definition
because the former are very common and the later require early intervention to improve the outcome
Term
what is the most frequently used criteria for polyps being benign?
Definition
multiplicity and size of up to 10mm
Term
Malignancy has been documented in 37-88% of resected polyps that were ______
Definition
10mm
Term
What are other malignancy risk factor?
Definition

older than 60

single lesion

gallstone disease

rapid changes in size on follow up

sessile morphology (have no peduncle but attached directly by a broad base)

Doppler:velocity of >20 cm/sec and an RI of <0.65

Term
Approximately 1/2 of all gb polyps are
Definition
cholesterol polyps
Term
cholesterol polyps represent ___________ form of gb cholesterolosis, a common non-neoplastic condition
Definition
focal
Term
How does cholesterolosis form?
Definition
results in the accumulation of lipids (triglycerides & cholesterol) in the gb wall
Term
What is the difference between polyps and stones?
Definition
polyps do no roll like stone and do not produce any posterior shadowing
Term
What is a diffused form of cholesterolosis called?
Definition
strawberry gb
Term
What are the symptoms of cholesterosis and how do they look sonographically?
Definition

cholesterosis is usually asymptomatic and if symptoms occur it's usually in the form of colicky abdominal pain

It appears similar to adenomyomatosis but do not have the comet tail reverberation artifact

Term
what are the 2 most common lesions that cause biliary obstruction?
Definition

gallstones

carcinoma of panc head

Term
What lab values are typically elevated which are associated with biliary obsruction?
Definition
serum alk. phos and bilirubin
Term
Obstuction of the distal CBD results in progressive dilation of the ______________
Definition
intra and extra hepatic biliary tree
Term
What are the other causes of biliary obstruction?
Definition

choledocholithiasis

pancreatic carcinoma

cholangiocarcinoma

cholangitis

mirizzi syndrome

choledochol cyst

gallbladder carcinoma

Term
what is dilated intrahepatic ducts?
Definition
irregular and tortuous bile ducts
Term
dilated intrahepatic ducts is aka?
Definition

parallel channel sign

shot gun sign

Term
How do you see dilated intrahepatic ducts sonographically?
Definition

stellate confluence: bile ducts that branch into a star shaped configuration

acoustic enhancement: bile structues attenuate sound much less than blood which creates posterior acoustic enhancement

Term
what happens to the biliary tree when there is a distal cbd obstruction?
Definition
the entire system distends including the gb
Term
what happens to the biliary tree when there is a chd obstruction?
Definition
only the proximal ducts will distend. the gb will be contracted
Term
what happens to the biliary tree when there is a RT & LT hepatic duct obstruction?
Definition
intrahepatic ducts dilate
Term
what are the biliary tract abnormalities?
Definition

choledochal cysts

caroli's disease

mirizzi syndrome

hemobilia

pneumobilia

acute (bacterial) cholangitis

recurrent pyogenic cholangitis

ascariasis

HIV cholangiopathy

Primary sclerosing cholangitis

cholangiocarcinoma

metastases

Term
These are congenital bile duct anomalies that consist of cystic dilation of intra or extra hepatic bile ducts -
Definition
choledochal cysts
Term
What is the most common classification of choledochal cyst? and what happens in this type?
Definition

Type I - most common

Fusiform dilation of the cbd resulting in a long channel between distal cbd and the mpv

Term
What is the rare classification of choledochal cyst?
Definition

type II - very rare

true diverticuli of the bile ducts

Term
What is type III clasification of choledochal cyst?
Definition

choledochoceles

confined to the intraduodenal portion of the cbd

Term
Where is type IVa & IVb seen in choledochal cyst?
Definition

IVa - multiple intra and extra hepatic biliary dilations

IVb - only extrahepatic

Term
How does choledochal cyst look like sonographically?
Definition

a cystic structure indentified which may contain internal sludge, stones or even solid neoplasm

because of a proven risk of cholangiocarcinoma with all choledochal cysts, surgical resection is advocated

ERCP necessary to ensure that the dilation is not a result of a distal neoplasm, especially in the case of type I choledochal cysts

Term
What is type V of choledochal cyst also known as?
Definition
caroli's disease
Term
What is a rare congenital anomaly of the biliary tract characterised by multifocal segmental dilation of the Intrahepatic bile ducts?
Definition
caroli's disease or type V
Term
What is the sonographic findings of caroli's disease?
Definition

multiple cystic structures that converge toward the porta hepatis communicating with the bile ducts

sludge and calculi may accumumate in these ectatic ducts that will result in posterior acoustic shadowing

Term
What are the clinical signs of Mirizze syndrome?
Definition

clinical syndrome of jaundice with pain and fever resulting from

compression of the chd

because of a stone in the cystic duct

(the stone is often impacted in the distal cystic duct and the accompanying inflammation and edema result in the obstruction of the adjacent CHD

Term
what is hemobilia?
Definition
blood clot in the biliary tree
Term
what is pneumobilia? what does it result from?
Definition

air within the biliary tree

results from previous biliary intervention, like biliary enteric anastomoses or cbd stents

Term
How does pneumobilia appear sonographically?
Definition

as intrahepatic linear echogenic regions that often produce distal acoustic shadowing

posterior dirty shadowing and reverberation artifacts are seen. Movement of the air bubbles, best seen just after changing the patient's position is diagnostic

Term
What is an essential component of bacterial cholangitis along with CBD stones?
Definition
antecedent (precursor) biliary obstruction
Term
What are the clinical presentation of acute (bacterial) cholangitis?
Definition

leukocytosis

elevated alkaline phosphatase and bilirubin

charcot's triad - fever, RUQ pain, jaundice

Term
What is the bile most commonly infected by for acute cholangitis?
Definition
infected by gram-negative enteric bacteria, which are often retrieved in blood cultures
Term
How does acute (bacterial) cholangitis seen sonographically?
Definition

choledocholihiasis and possible sludge

bile duct wall thickening

dilation of the biliary tree

hepatic abscesses

Term
HIV cholangiopathy is also known as -
Definition
AIDS cholangitis
Term
what is an inflammatory process affecting the biliary tree in the advanced stages of HIV infection
Definition
HIV cholangiopathy  or AIDS cholangitis
Term
What does the patient present for HIV cholangiopathy?
Definition
severe RUQ or epigastric pain, markedly elevated alkaline phosphatase but normal bilirubin levels
Term
What are the findings for HIV cholangiopathy?
Definition

bile duct wall thickening, intra & extra hepatic

focal structures and dilations

cbd dilation

diffuse gb wall thickening

Term
What is a chronic disease process that effects the entire biliary tree?
Definition
primary sclerosing cholangitis
Term
irregular, circumferential bile duct wall thickening of varying degrees, encroaching on and narrowing the lumen is seen in which disease?
Definition
primary sclerosing cholangitis
Term
focal strictures and dilations of the bile ducts are ensured in
Definition
primary sclerosing cholangitis
Term
____________ develops in 7-30% of patients with primary sclerosing cholangitis
Definition
cholangiocarcinoma
Term
primary sclerosing cholangitis is seen in
Definition
intra & extra hepatic stricture
Term
What are parasitic roundworm in the biliary tree called?
Definition
ascariasis
Term
how is ascariasis formed?
Definition
by use of fecal oral route and most common in children
Term
How does ascariasis enter the biliary tree?
Definition
ascariasis is active within the small bowel and may enter the biliary tree retrogradely through the ampulla of vater, causing biliary obstruction
Term
A parrallel echogenic line within the bile ducts, which also can be similar in appearance of a biliary stent is appeared for which disease?
Definition
ascariasis
Term
How does ascariasis look transversely?
Definition
rounded worm surrounded by the bile duct gives a target appearance
Term
What is associated with gallstones, chronic gallstones disease and resultant dysplasia?
Definition
gb carcinoma
Term
Mass arising in the gb fossa, obliterating the gb and invading the adjacent liver is a pattern of which disease?
Definition
gb carcinoma
Term
focal or diffuse, markedly abnormal and irregular wall thickening pattern is associated with which disease?
Definition
gb carcinoma
Term
intraluminal polypoid mass pattern is associated with which desease?
Definition
gb carcinoma
Term
what are the patterns of tumor spread?
Definition

contiguous hepatic spread

lymphatic spread

Term
Why is contiguous hepatic invasion the most common pattern of spread in gb tumor?
Definition
because the gb wall is quite thin and little connective tissue separates it from the liver parenchyma
Term
how does the gb tumor mimic hilar cholangiocarcinomas?
Definition
gb tumors also extend along the cystic duct into the porta hepatis, where they mimic hilar cholangiocarcinomas
Term
__________ spread of the gb tumor may occur in the absence of invasion of the adjacent organs
Definition
lymphatic spread
Term
where is the first nodes affected in the lympatic spread of gb tumor?
Definition
Hilar region (hilar: depression or recess at exit or entrance of a duct into a gland or of nerves and vessels into an organ
Term
masses replacing the normal gb fossa when small, may be difficult to appreciate because they may blend into the liver is a sonographic appearance of which disease?
Definition
gb tumor spread
Term
the absence of a normal appearing gb with no history of cholecystectomy should raise suspicion of which disease?
Definition
gb tumor spread
Term
primary gb adenocarcinomas may appear as a ______________
Definition
polypoid mass
Term
hyperechoic, broad based polyps may be multiple is the appearance of ____________
Definition
gb adenocarcinomas
Term
_________ or _________ are 2 types of cholangiocarcinoma
Definition
intrahepatic or extrahepatic
Term
what happens to any portion of the biliary tree in a cholangiocarcinoma?
Definition
uncommon neoplasm may arise
Term
which is the least common but represents the 2nd most common primary malignancy of the liver?
Definition
intrahepatic cholangiocarcinoma
Term
Large hepatic mass, hypovascular, solid with heterogeneous echotexture is the most common finding of which disease?
Definition
intrahepatic cholangiocarcinoma
Term
what are the risk factors for intrahepatic cholangiocarcinoma?
Definition

primary sclerosing cholangitis (most common)

chronic biliary stasis and inflammation

Term
Hilar is aka
Definition
klatskins
Term
where does the patterns of tumor growth and staging begin?
Definition
in either the right or left bile ducts and extends both proximally into higher order branches and distally into the chd and contralateral bile ducts
Term
Where can the tumor of the gb also extend to?
Definition
outside of the ducts to involve adjacent portal vein and arteries
Term
nodal disease often begins in the ____________
Definition
porta hepatis
Term
mets is usually to the _________
Definition
liver
Term
what mimics different appearances of cholangiocarcinoma and affects both intra and extra hepatic ducts?
Definition
metastases
Term
what sites constitue the majority of primary metastases malignancy?
Definition
breast, colon & melanoma
Term
what is the most common malignant neoplasm that obstructs the biliary tree?
Definition
pancreatic adenocarcinoma
Term
pancreatic adenocarcinoma at the head of the pancreas typically causes __________
Definition
courvoisier gb
Term
an enlarged, often palpable gallbladder in a patient with carcinoma of the head of the pancreas which is associated with jaundice due to obstruction of the common bile duct is called?
Definition
couvoisier gb
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