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Ultrasound - (Fall)
Pancreas normal & abnormal
111
Medical
Professional
10/28/2009

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Cards

Term
The pancreas is a ____________, ___________ sturcture
Definition
non-encapsulated, retroperitoneal
Term
Between what does the pancreas lie?
Definition
between the duodenal loop and the splenic hilum
Term
What is the pancreas divided into?
Definition

head

uncinate process

neck

body

tail

Term
What is the normal measurement of panc?
Definition
between 12-15cm
Term
Which is the most bulbous part of the panc which narrows at the neck?
Definition
Head of panc
Term
What is the head measurement of the panc?
Definition
<3cm
Term
What anatomic position marks the pancreatic neck?
Definition
the porto-splenic confluence
Term
what does the panc neck measure?
Definition
10mm
Term
What lies anterior to the body of panc?
Definition
lesser sac
Term
How does the splenic vein run along with the panc?
Definition
splenic vein runs along its posterosuperior surface
Term
what is the measurement of the panc body?
Definition
1.5cm
Term
What is the tail of the panc related to?
Definition
the tail of the panc is related to the spleen, left adrenal glands, and upper pole of the left kidney
Term
what is the measurement of the panc tail?
Definition
2.4cm
Term
What extends inferior to the main body of the panc?
Definition
the uncinate process
Term
what are the functions of the pancreas?
Definition

exocrine

endocrine

Term
What does exocrine secret?
Definition
exocrine secretes trypsin, lipase & amylase
Term

Through what does the exocrine secrete trypsin, lipase & amylase?

How much does the exocrine comprise of?

Definition

the ductal system

acinar cells

80% of the panc tissue

Term
What does endocrine secret, through what?
Definition
secretes insulin via the islets of langerhans
Term
How much does the endocrine form of the panc?
Definition
2% of the panc tissue
Term
What does the remaining 18% of the panc tissue consist off?
Definition
consists of fibrous stroma that contains blood vessels, nerves and lymphatics
Term
What are the lab values for panc?
Definition
amylase and lipase
Term
What is the digestive enzyme for carbohydrates?
Definition
amylase
Term
Which organ produces amylase?
Definition
pancreas and salivary gland
Term
when does the amylase level increase?
Definition
if there is a dysfunction of the salivary gland and panc and kidney disease
Term
What is parallel to the amylase level? What happens when amylase level rise?
Definition

Lipase

Amylase level rise first and lipase level rise later but persist longer

Term
What is the panc texture in ultrasound?
Definition
the normal panc is homogenous with the echogenicity
Term
What is the echotexture of the panc when compared to the liver?
Definition
is isoechoic or more commonly hyperechoic
Term
what happens to the texture of the panc due to age and obisity?
Definition

it becomes more echogenic as a result of presence of fatty infiltration

this is reversible

Term
What must a tech do to visualize the panc?
Definition

the patient is in LLD and drinks water to fill the stomach

while scanning the patient is then turned to supine or RLD position where water in the stomach and duodenum is used as an acoustic window

Term
What organ lies on the anterior border of the panc body and tail?
Definition
the posterior wall of the stomach
Term
What is the relation of the duodenal loop with the panc?
Definition
the duodenal loop, except for the 1st segment, encircles the panc head
Term
Head of the panc is anterior to the?
Definition
IVC
Term
Head of the panc is medial to the?
Definition
duodenum
Term
CBD is ______ to the panc head
Definition
posterior
Term
GDA is ________ to the panc head
Definition
anterior
Term
SMA and SMV are _______ to the panc neck
Definition
posterior
Term
SMA and SMV are _________ to the uncinate process and 3rd portion of the duodenum
Definition
anterior
Term
The abd aorta runs ________ to the panc body
Definition
posterior
Term
The celiac axis arises from the aorta at the _________ border of the panc
Definition
superior
Term
The CHA proceeds _________ to the ______, _______ to the panc head
Definition
anterior, right, cephalad
Term
The ___________ artery follows a tortuous course along the superior border of the panc body and tail
Definition
splenic
Term
how does the splenic vein course with the panc?
Definition
splenic vein runs from its origin in the splenic hilum along the posteroinferior aspect of the panc to join the smv
Term

The SMV and Splenic vein join _______ to the panc neck to form the ___________.

The MPV ascends towards the pora hepatis __________ to the panc head

Definition
posterior, portal confluence, cephalad
Term
Where does the CBD travel to the 1st portion of the duodenum and the panc head?
Definition
CBD travels posterior to the 1st portion of the duodenum and the panc head to lie to the right of the main pancreatic duct and opens into the duodenum at the ampulla of vater after forming a common trunk with the MPD
Term
Duodenum is divided into how many portion? What are they?
Definition

4

1st and 3rd portion are transverse

2nd and 4th portions are longitudinal

Term
The main pancreatic duct is aka
Definition
duct of wirsung
Term
When is the normal pancreatic duct considered abnormal?
Definition
if it is >2mm
Term
When is panc duct dilated?
Definition

due to stone within the duct of wirsung from chronic pancreatitis or

a  stone at the ampulla of vater

Term
What is the duct of santorini aka?
Definition
accessory duct
Term
What does the accessory duct do?
Definition
it branches off the MPD in the pancreas head and drains the uncinate process
Term
absence of the body and tail with the remaining pancreatic head showing compensatory hypertrophy is what kind of anomaly?
Definition
congenital anomalies of panc
Term
What is the disease called when panc has multiple cysts that are associated with adult type polycystic kidney disease
Definition
congenital cysts
Term
what is the disease that is characterized by viscous secretions and dysfunction of multiple glands, including the panc, leading to pancreatic insufficiency 
Definition
cystic fibrosis
Term
In which disease does the panc have increased echogenicity and is shrunk with marked fibrosis, fatty replacement and cysts secondary to the obsruction of small ducts?
Definition
cystic fibrosis
Term
What is the failure of the dorsal and ventral panc duct to fuse during embryonic development?
Definition
panc divisum
Term
what is the most common congenital variant of pancreatic anatomy?
Definition
pancreas divisum
Term
what results due to pancreas divisum? and what is it associated with?
Definition
the smaller santorini's ducts drain the body and tail and is associated with pancreatitis
Term
what is the uncommon congenital anomaly called where a ring of normal panc tissue encircles the duodenum seconday to the abnormal migration of the ventral panc?
Definition
annular pancreas
Term
Why is annular pancreas in children frequently diagnosed in infancy?
Definition
because of associated duodenal obstruction
Term
what is the inflammatory disease producing temorary pancreatic changes?
Definition
acute pancreatitis
Term
what is the most common cause of acute pancreatitis?
Definition

biliary tract disease

chronic etoh abuse

Term
what sonographic findings do you see for acute pancreatitis?
Definition
enlarged hyperechoic gland but may be negative in milder forms of acute pancreatitis
Term
What are the complications of acute pancreatitis?
Definition

pseudocyst formation

abscess

pancreatic necrosis

hemorrhage

splenic vein thrombosis

pseudoaneurysm formation

 

Term
What else is visualised during acute pancreatitis?
Definition
ductal dilation, mass effect from phlegmon or hemorrhage, peripancreatic fluid collections, thickening of adjacent fascial planes and ascites
Term
What is mostly seen in the panc head?
Definition
focal pancreatitis
Term
What is difficult to differentiate from a neoplasm?
Definition
focal pancreatitis
Term
With normal amylase what is a pancreatic mass likely to represent?
Definition
a neoplasm
Term
What is likely to be associated with pancreatitis in the pediatric patient?
Definition
choledochal cysts, cystic fibrosis (most common) or hereditary autosomal dominant pancreatitis
Term
when does pancreas become increasingly hypoechogenic relative to normal liver and increases in size?
Definition
Diffuse pancreatitis
Term
What is the most common cystic lesion of the pancreas?
Definition
pseudocysts
Term
What does the cystic lesion of the pancreas contain?
Definition
accumulation of pancreatic fluid and necrotic debris confined by the retroperitoneum that contains high amounts of amylase, lipase and trypsin
Term
Explain the wall of the pancreatic pseudocyst?
Definition
Generally spherical and take 4-6 weeks to enclose itself by forming a wall composed of collagen and vascular granulation tissue
Term
What is pancreatic pseudocyst commonly associated with?
Definition
alcoholic or biliary etiology or after blunt abd trauma in children or secondary to pancreatic malignancy
Term
What symtoms are seen with pancreatic pseudocyst?
Definition
persistent pain and elevated amylase levels
Term
how does the pancreatic pseudocyst look?
Definition

a well defined, smooth walled anechoic structure with acoustic enhancement

Debris may occur within it due to hemorrhage or infection

 

Term
What are the complications from a pseudocyst?
Definition
may become large and cause obstruction of the stomach, small bowel, colon or bile ducts, progressing to jaundice and obstructive cholangitis
Term
what must be done if a pseudocysts persist beyone 6 weeks or grow larger than 5cm in diameter with evidence of regression?
Definition
require non-surgical decompression
Term
What is a irreversible destruction to the panc due to repeated bouts of pancreatic inflammation?
Definition
chronic pancreatitis
Term
What happens to the panc with chronic pancreatitis?
Definition
the fibrous connective tissue proliferates around the ducts and between the lobules, causing interstitial scarring. This leads to an irregular, nodular appearance of the panc surface
Term
What are the causes of chronic pancreatitis?
Definition

alcoholism

hereditary pancreatitis

cystic fibrosis

congenital abnormalities

blunt abdominal trauma

idiopathic chronic pancreatitis

Term
How does cronic pancreatitis look sonographically?
Definition

small echogenic pancreas

calcifications

pancreatic duct dilatation

pseudocyst formation

bile duct dilatation

portal vein thrombosis

Term
What is a phlegmon pancreatitis?
Definition
is a non-encapsulated inflammatory process that spreads along peripancreatic tissue, causing localized areas of diffuse inflammatory edima of soft tissue that may proceed to necrosis and suppuration
Term
How does the phlegmon pancreatitis look sonographically?
Definition
it appears hypoechoic with good through transmission
Term
What is the 10th most common malignancy and the 4th largest cancer killer in adults and has a dismal prognosis for which reaason surgical resection is the only chance for cure in the pancreas?
Definition
pancreatic neoplasms / cancer
Term
What does patients with pancreatic carinoma (adenocarcinoma) present?
Definition
lymphatic and metastatic spread of the tumor
Term
What are the symptoms of adenocarcinoma?
Definition

abd pain

jaundice

Term
what is the sonographic finding of adenocarcinoma of the panc?
Definition
solid hypoechoic mass, usually in the panc. head that is poorly defined
Term
what are other finding associated with adenocarinoma of the panc?
Definition

bile duct dilatation (courvoisier's GB)

painless jaundice

dilated pancreatic duct

pancreatitis

liver mets

ascites

lymphadenopathy around the aorta

pseudocyst formation

Term
what are the lab finding for adenocarcinoma of the panc?
Definition

elevated bilirubin

elevated Alk. phos

amylase may be elevated

Term
what is typically seen in patients with a pancreatic head tumor?
Definition
dilatation of the common bile duct and pancreatic duct (double duct sign)
Term
what is the most striking clinical symptom leading to the diagnostic imaging for pancreatic adenocarcinoma?
Definition
painless obstructive jaundice, which is caused by compression or ingrowth of distal common bile duct
Term
How is pancreatic cancer treated?
Definition

surgery

chemotherapy

radiation therapy

palliative care

Term
What are the surgical procedures offered for pancreatic cancer?
Definition

whipple procedure

distal pancreatectomy and splenectomy

Term
what is the whipple procedure aka?
Definition
pancreaticoduodenecomy
Term
why is the whipple/pancreaticoduodenectomy performed?
Definition
due to cancer in the panc head
Term
How is the whipple/pancreaticoduodenectomy procedure performed?
Definition
the head of the pancreas, a portion of the bile duct, the gb and duodenum are removed. the remaining panc and bile duc are sutured back to the intestines to direct secretions back to the gut
Term
how is the distal pacreatectmy and splenectomy procedure performed?
Definition
a distal pancreatectomy is the removal of the end of the panc while leaving the pancreatic head attached. It is performed to treat pancreatic cancer localised in the end of the pancreas, but may also be used for chronic pancreatitis, pancreatic pseuodcysts and injury due to trauma. when the disease affects the splenic artery or vein the adjacent spleen is often removed
Term
Which is the benign cystic neoplasm of the pancreas?
Definition
serous cystadenoma
Term
how does the serous cystadenoma look sonographically?
Definition

cluster of grapes pattern

when cysts are small, the mass may be echogenic and appear solid with through transmission

Term
which is malignant or potentially malignant cystic neoplasm of the panc?
Definition
mucinous cystic
Term
how does mucinous cyst look like sonographically?
Definition

well-defined multicystic mass (large cysts)

increased CEA lab test

Term
What is an endocrine tumores common in the body and tail which is uncommon?
Definition
islet cell tumors
Term
What is the most common islet cell tumor? what does it cause and is it benign or malignant?
Definition

insulinoma

causes hypoglycemia

usually benign

Term
what is the 2nd most common islet cell tumor?
Definition
gastrinoma
Term
what is gastrinoma aka?
Definition
zollinger-ellison syndrome
Term
what symptoms occur in gastrinoma? are they malignant or benign?
Definition

gastric acid hypersecretion and  duodenal ulceration

frequently malignant

Term
What is a group of heritable syndromes characterized by abherant growth of benign or malignant tumors in a subset of endocrine tissues?
Definition
multiple endocrine neoplasia (MEN)
Term
What does MEN I tumors involve?
Definition

parathyroid glands

endocrine pancreas

the pituitary

Term
what does MEN IIa involve?
Definition
medullary carcinoma of the thyroid gland, pheochromocytoma and hyperparathyroidism
Term
What does MEN IIB tumor involve?
Definition
medullary carinoma of the thyroid multiple neuromas, and pheochromocytoma
Term
what is multiple endocrine neoplasia associated with?
Definition

insulinoma

gastrinoma

medullary thryoid carcinoma

pheochromocytoma

parathyroid gland hyperplasia

pituitary tumors

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