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UCI: Brain Disorders Lecture 16 Terms
Frontal Disorders
10
Psychology
Undergraduate 4
12/01/2010

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Term
Phineas Gage
Definition
A railroad foreman who had a railroad rod shoot through his prefrontal cortex (and face) that survived and had drastic personality changes as a result.
Term
Lobotomy
Definition
A procedure where ice picks are placed in the orbital sockets, up into the prefrontal cortex and wiggled around, destroying tissue, in order to treat a wide variety of mental illnesses
Term
Dorsolateral Prefrontal Cortex
Definition
The highest cortical area responsible for motor planning, organization, and regulation, which is involved in the integration of sensory and memory information and the regulation of intellectual function and action, and is also involved in working memory.
Term
Frontal Convexity Syndrome
Definition
A disorder characterized by apathy, indifference, occasional outbursts, stimulus-bound behavior, lacking of planning, psychomotor retardation, motor perseveration and programming deficits, poor word list generation, poor abstraction and categorization, and working memory deficits.
Term
Perseveration
Definition
Persistent use of a specific strategy to solve a problem, despite the fact that strategy is wrong or the rule of the task has changed
Term
Anterior Cingulated Cortex
Definition
Part of cortex that subserves primarily executive functions related to the emotional control of visceral, skeletal, and endocrine outflow
Term
Medial Frontal Syndrome
Definition
A syndrome characterized by the paucity of spontaneous movement and gesture, sparse verbal output, lower extremity weakness and loss of sensation, and incontinence.
Term
Orbitofrontal Cortex
Definition
The cortex that is involved in sensory integration, affective value of reinforcers, decision making, expectation, taste, flavor, and regulates planning behavior associated with sensitivity to reward and punishment
Term
Orbitofrontal Syndrome
Definition
A syndrome characterized by disinhibited, impulsive behavior, inappropriate jocular affect, emotional lability, poor judgement and insight, sexual disinhibition, lack of concern for others, and distractibility.
Term
Antisocial Personality Disorder
Definition
A disorder characterized by a failure to conform to social norms with respect to lawful behaviors, deceitfulness, impulsivity, failure to plan ahead, irritability, aggressiveness, reckless disregard for safety of self or others, consistent irresponsibility, lack of remorse, rationalization of crimes, superficial charm, and substance abuse.
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