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Tuberculosis
Test 3 Sem 2
19
Medical
Graduate
02/17/2011

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Cards

Term
Tuberculosis is 200x more common in what demographic?
Definition
HIV positive
Term
What diameter induration should be considered positive in HIV, high risk patients? Everyone else?
Definition
HIV-5mm
High Risk - 10mm
Everyone else - 15mm
Term
What tests are used to diagnosis TB?
Definition
Nucleic Acid Amplification (NAA) and cultures
Term
How do 90% of Primary infections manifest?
Definition
asymptomatic w/normal CXR
Term
What is the most common symptomatic presentation of pulmonary TB?
Definition
atypical pneumonia
Term
Extrapulmonary TB is most common in whom?
Definition
HIV patients
Term
What is the most common clinical form of TB?
Definition
Reactivation (post-primary) TB
Term
What is the most rapidly progressive form of TB?
Definition
TB meningitis
Term
What is the most common extra-thoracic form of TB?
Definition
Renal TB
Term
all HIV patients with an induration of 5mm or more should receive what drug and for how long?
Definition
isoniazid for 9 months
Term
Prophylaxis in HIV-negative patients
1) Recent converter
2) less risk factors
3) no risk factors
Definition
1) >5mm - INH
2) < 35yo and >10mm - treat, >35yo and >15mm - treat.
3) <35 yo and >15mm - INH
Term
What tests must be done before Anti-TB chemotherapy is given?
Definition
cultures and sensitivities
Term
When can you discharge someone from the hospital who was admitted for TB?
Definition
after 3 consecutive negative sputum cultures and clinical improvement
Term
According to the lecturer what are the 4 TB meds used?
Definition
1) Isoniazid (INH)
2) Rifampin
3) Pyrazinamide
4) Ethambutol or Streptomycin
Term
What is a major toxicity of Isoniazid?
Definition
peripheral neuropathy
Term
What is a major side effect of Rifampin?
Definition
orange discoloration of urine, sweat, tears and saliva
Term
What is the most common opportunistic bacterial infection in AIDS patients?
Definition
Mycobacterium avium
Term
Treatment plan for mycobacterium avium?
Definition
Antiretroviral therapy-control AIDS-may control infection.

Azithromycin/Clarithromycin
Term
What is characteristic of Leprosy and what causes it?
Definition
mutilation caused by sensory loss
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