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TSM 49
Symptoms and clinical signs of eye disease
16
Medical
Undergraduate 2
12/26/2012

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Cards

Term
What is the effect of a lesion in the macula?
Definition
Unilateral central scotoma with distortion.
Term
What is the effect of a lesion in the peripheral retina eg. detachment
Definition
Unilateral peripheral/ total.
Term
What is the effect of a lesion in the optic nerve (acute)?
Definition
Unilateral central scotoma.
Term
What is the effect of a lesion in the Optic Nerve (Chronic)
Eg Glaucoma, chronic papilloedema
Definition
Peripheral constriction (tunnel vision)
(also seen in functional visual loss)
Term
What is the effect of a lesion in the chiasm?
Definition
Bitemporal Hemianopia (Outer field loss in both eyes).
Term
What is the effect of a lesion post chiasm
Definition
Loss of field opposite to site of lesion in both eyes
Eg left optic tract lesion causes inner field loss in left eye and outer field loss in right eye.
Term
What is the pupil light reaction?
Definition
When light is shone in one eye, both pupils constrict (direct and consensual).
Term
What can cause total afferent pupil defect in one eye?
Definition
Sectioned optic nerve or retina totally detached.
Term
What would you observe in a patient with total afferent pupil defect in one eye?
Definition
-Both pupils the same at rest
-No constriction of affected eye
-Consensual response present
-When light moved from normal to affected eye both pupils dilate.
Term
What does relative afferent pupil defect indicate?
Definition
Widespread unilateral retinal or optic nerve pathology.
Term
What is the main sign of an efferent pupil defect?
Definition
Pupils are different sizes at rest.
Term
What causes a failure of the pupil to constrict?
Definition
Damage to the preganglionic nerve which travels from the midbrain to the orbit with the third nerve or the postganglionic nerve which travels from the ciliary ganglion to the eye.
Term
What conditions are normally responsible for a failure of the pupil to constrict?
Definition
1) A compression of the preganglionic nerve by brain swelling or an aneurysm in the circle of willis
2) Damage as part of a third nerve palsy
3) A lesion of the ciliary ganglion.
4) Pathology of the pupil sphincter
Term
What does damage to the sympathetic supply to the eye cause?
Definition
Horner's syndrome.
Term
What are the main symptoms of Horner's syndrome?
Definition
Failure of pupil dilation
Partial Ptosis (drooping of eyelid)
If preganglionic:
-Anhydrosis
(Failure to sweat on affected side)
-Absence of flushing
If congenital (or onset prior to 12 months):
-Iris heterochromia
Term
What can cause Horner's syndrome?
Definition
Lesions:
1) Preganglionic from T1 to superior cervical ganglion
2) Postganglionic from SCG to eye via ICA via long posterior ciliary nerves
3) Pathology of the pupil dilator eg. uveitis
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