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TSM 22
Development of the head and neck
24
Medical
Undergraduate 2
01/08/2013

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Cards

Term
How many pharyngeal arches are there and what structures are associated with them?
Definition
5 (1, 2, 3, 4, 6). Each arch has an associated cranial nerve and arch artery.
Term
What does the first arch membrane become?
Definition
The tympanic membrane.
Term
What does the first cleft become?
Definition
The external auditory meatus.
Term
What does the first arch become?
Definition
1) Meckel's cartilage in the mandible and bones of the middle ear
2) Muscles of mastication.
Term
What does the second arch become?
Definition
1) The styloid process and upper part of the hyoid bone
2) Muscles of facial expression.
Term
What does the third arch become?
Definition
1) Lower part of hyoid.
2) Stylopharyngeus.
Term
What does the fourth arch become?
Definition
1) Thyroid and cricoid cartilage
2) Pharyngeal and soft palate muscles.
Term
What does the sixth arch become?
Definition
1) Arytenoid cartilage.
2) Intrinsic laryngeal muscles.
Term
What is the nerve supply to the 1st and 2nd arches?
Definition
CN V (trigeminal).
Term
What is the nerve supply to the third arch?
Definition
CN VII (facial).
Term
What is the nerve supply to the 4th arch?
Definition
CN IX (glossopharyngeal).
Term
What is the nerve supply to the 6th arch?
Definition
CN X (vagus).
Term
What does each cranial nerve supplying a typical arch contain?
Definition
1) Brachiomotor neurons
2) General sensory neurons
3) Visceral sensory neurons.
Term
What is the fate of pharyngeal arch arteries?
Definition
They are remodelled to form the aorta and pulmonary trunk.
Term
What does the first pouch become?
Definition
The auditory tube.
Term
What are the fates of teh 2nd, 3rd and 4th clefts?
Definition
They become the cervicl sinus.
Term
What does the 2nd pouch become?
Definition
The palatine tonsil.
Term
What does the 3rd pouch become?
Definition
The parathyroid gland (inferior) and thymus.
Term
What does the 4th pouch become?
Definition
The parathyroid gland (superior).
Term
What is the consequence of a failure clefts 2-4 to close?
Definition
A brachial cyst. It remains stationary on swallowing.
Term
How do the nose and lips form?
Definition
Upper/ lower lip: a fusion of the right and left maxillary/ mandibular processes
Nose: Endodermal nasal placode covers the frontonasal process.
Term
Name the 4 kinds of cleft palate.
Definition
1) Unilateral cleft lip
2) Midline cleft palate
3) Bilateral cleft lip and palate
4) Bilateral cleft lip and palate continuous with cleft of secondary palate.
Term
What does Treacher Collin's syndrome arise from?
Definition
Hereditary defect in development of 1st arch neural crest.
Term
What are Del22q11.2 syndrome and Pierre Robin sequence caused by?
Definition
A neural crest cell genetic defect.
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