Term
|
Definition
dnK
up lips
up urea
lassitude
upCa
upGlu |
|
|
Term
|
Definition
K waste
met alk
hypoTN
ototoxfurosemide & butamide |
|
|
Term
SE: dnK
up lips
up urea
lassitude
upCa
upGlu |
|
Definition
|
|
Term
SE: K waste
met alk
hypoTN
ototox |
|
Definition
loop diuretics
furosemide & butamide |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
dn preload
dn afterload
dn remodeling |
|
|
Term
| MOA: diuretics & vasodilators for HTN |
|
Definition
|
|
Term
|
Definition
| dry mouth, sedn, severe rebound HTN |
|
|
Term
|
Definition
| impotence, asthma, CV SE (bradycardia, CHF, av block), CNS SE |
|
|
Term
|
Definition
use w/ BB to avoid reflex tachy
(lupus-like & salt ret'n) |
|
|
Term
|
Definition
| Cough, Angioedema, Proteinuria, Taste changes, hypOtn, Preg: fetal renal dmg, Rash, Incr renin, hyperkaLemia |
|
|
Term
|
Definition
|
|
Term
|
Definition
up cGMP->sm mm relax.
vasodiln>veins -> dn afterload |
|
|
Term
|
Definition
|
|
Term
|
Definition
verapamil
nifedipine
diltiazem |
|
|
Term
verapamil
nifedipine
diltiazem |
|
Definition
|
|
Term
|
Definition
dn contr & sm mm relax
VSM: N>D>V
heart: V>D>N |
|
|
Term
|
Definition
| HTN, angina, arrhythmias (not nifedipine) |
|
|
Term
|
Definition
vasodilate (NO) ->up cGMP ->sm mm relax
veno>>vaso diln (dn preload) |
|
|
Term
|
Definition
|
|
Term
up cGMP->sm mm relax.
vasodiln>veins -> dn afterload |
|
Definition
|
|
Term
dn contr & sm mm relax
VSM: N>D>V
heart: V>D>N |
|
Definition
|
|
Term
vasodilate (NO) ->up cGMP ->sm mm relax
veno>>vaso diln (dn preload) |
|
Definition
|
|
Term
|
Definition
| reduce myocard O2 consumption by decr EDV, BP, HR, contr or ejection time |
|
|
Term
|
Definition
| inh Na/K -> up IC Na -> up IC Ca -> pos inotropy |
|
|
Term
| inh Na/K -> up IC Na -> up IC Ca -> pos inotropy |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
bronchocontstr
vasoconstr
sm musc contr
up vasc perm |
|
|
Term
|
Definition
|
|
Term
| up bronchial tone (factors) |
|
Definition
|
|
Term
bronchocontstr
vasoconstr
sm musc contr
up vasc permup bronchial tone |
|
Definition
|
|
Term
|
Definition
inh platelet aggr
vasodiln |
|
|
Term
inh platelet aggr
vasodiln |
|
Definition
|
|
Term
|
Definition
dn PLA2
dn COX synth
beclomethasone, prednisone
via dn TNFa |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
dn platelet aggr
dn vasc tone
dn bronch tone
dn uterine tone |
|
|
Term
dn platelet aggr
dn vasc tone
dn bronch tone
dn uterine tone |
|
Definition
|
|
Term
|
Definition
up uterine tone
dn vasc & bronch tone |
|
|
Term
up uterine tone
dn vasc & bronch tone |
|
Definition
|
|
Term
|
Definition
up platelet aggr
up vasc&bronch tone |
|
|
Term
up platelet aggr
up vasc&bronch tone |
|
Definition
|
|
Term
|
Definition
diphenhydramine
dimenhydrinate
chorpheniramine |
|
|
Term
|
Definition
allergy
motion sickness
sleep aid |
|
|
Term
|
Definition
loratadine
fexofenadine
desloratadine |
|
|
Term
allergy
motion sickness
sleep aid |
|
Definition
|
|
Term
diphenhydramine
dimenhydrinate
chorpheniramine |
|
Definition
|
|
Term
|
Definition
sedn
antimusc
anti-a-adrenergic |
|
|
Term
sedn
antimusc
anti-a-adrenergic |
|
Definition
|
|
Term
|
Definition
|
|
Term
loratadine
fexofenadine
desloratadine |
|
Definition
|
|
Term
|
Definition
B2ag-> relax broncSM
but tachy (B1) |
|
|
Term
|
Definition
B2 ag
use during acute asthma attack |
|
|
Term
|
Definition
long acting B2 ag for asthma prophylaxis
SE: tremor, arrhythm |
|
|
Term
B2 ag
use during acute asthma attack |
|
Definition
|
|
Term
long acting B2 ag for asthma prophylaxis
SE: tremor, arrhythm |
|
Definition
|
|
Term
|
Definition
inh phosphodiesterase -> dn cAMP hydrolysis
narrow ther window (card & neurotox) |
|
|
Term
| inh phosphodiesterase -> dn cAMP hydrolysis |
|
Definition
theophylline
(methylxanthine)
narrow ther window (card & neurotox) |
|
|
Term
|
Definition
| blocks muscR-> prevents bronchoconstr |
|
|
Term
| blocks muscR-> prevents bronchoconstr |
|
Definition
|
|
Term
|
Definition
prevents mast cell release of mediators
prophylactic |
|
|
Term
prevents mast cell release of mediators
prophylactic |
|
Definition
|
|
Term
|
Definition
up PR
dn QT
scoop ST
twave inv |
|
|
Term
|
Definition
|
|
Term
|
Definition
Na: dn condn (esp in depol cells)
slow phase 4 depol (state dependent)
up threshold for firing in abnl pacemakers |
|
|
Term
|
Definition
quinidine, procainamide, disopyramide, (amiodarone)
up AP dur'n, up refr period, up QT
effect A&V arrhyth |
|
|
Term
|
Definition
lidocaine (mexiletine & tocainide: PO)
dn AP durn
affect isch & depol Purk & ventr
rx: ventr arrhythm esp post MI |
|
|
Term
|
Definition
flecainide, propafenone
no effect on AP but slow condn but -> arrhythm
Rx: vtach->VF; SVT |
|
|
Term
|
Definition
BB: dn cAMP, dn CA current.
Suppress abnl pacemakers (phase 4) esp AV node.
Up PR
may mask hypoglycemia |
|
|
Term
|
Definition
sotalol, ibutilide, bretylium, amiodarone
up AP durn, up refr period, up QT
check LFT, PFT, TFT
recurrent V arrhythms
->torsades |
|
|
Term
|
Definition
CCB: verapamil, diltiazem
AV node: slow condn, up refr, up PR
rx: prevent SVT, VT, nodal arrhythm
SE: torsades |
|
|
Term
|
Definition
|
|
Term
|
Definition
| ectopic pacemakers (dig tox) |
|
|
Term
|
Definition
|
|
Term
Na: dn condn (esp in depol cells)
slow phase 4 depol (state dependent)
up threshold for firing in abnl pacemakers |
|
Definition
|
|
Term
up AP dur'n, up refr period, up QT
effect A&V arrhyth |
|
Definition
quinidine, procainamide, disopyramide, (amiodarone)
class Ia antiarrythmics |
|
|
Term
dn AP durn
affect isch & depol Purk & ventr
rx: ventr arrhythm esp post MI |
|
Definition
lidocaine (mexiletine & tocainide: PO)
class Ib antiarrythmics |
|
|
Term
no effect on AP but slow condn but -> arrhythm
Rx: vtach->VF; SVT |
|
Definition
flecainide, propafenone
class Ic antiarrythmics |
|
|
Term
Suppress abnl pacemakers (phase 4) esp AV node.
Up PR
may mask hypoglycemia |
|
Definition
BB: dn cAMP, dn CA current.
class II antiarrythmics |
|
|
Term
up AP durn, up refr period, up QT
check LFT, PFT, TFT |
|
Definition
sotalol, ibutilide, bretylium, amiodarone
class III antiarrythmics |
|
|
Term
AV node: slow condn, up refr, up PR
rx: prevent SVT, VT, nodal arrhythm
SE: torsades |
|
Definition
CCB: verapamil, diltiazem
class IV antiarrythmics |
|
|
Term
| AV nodal arrhythmias (class v) |
|
Definition
|
|
Term
| ectopic pacemakers (dig tox) (class v) |
|
Definition
|
|
Term
| torsades, dig tox (class v) |
|
Definition
|
|
Term
| class Ia antiarrythmics RX |
|
Definition
A&V arrhyth
maintain sinus after Afib cardioversion |
|
|
Term
| class Ib antiarrythmics RX |
|
Definition
| ventr arrhythm esp post MI |
|
|
Term
| class Ic antiarrythmics RX |
|
Definition
vtach->VF (refr)
SVT
atrial: WPW |
|
|
Term
| class II antiarrythmics RX |
|
Definition
| Suppress abnl pacemakers (phase 4) esp AV node NOT CHF |
|
|
Term
| class III antiarrythmics RX |
|
Definition
recurrent V arrhythms
check LFT, PFT, TFT
->torsades |
|
|
Term
| class IV antiarrythmics RX |
|
Definition
prevent SVT, VT, nodal reentry
htn, angina
SE: torsades |
|
|
Term
| class Ia antiarrythmics phys effect |
|
Definition
| up AP dur'n, up refr period, up QT |
|
|
Term
| class Ib antiarrythmics phys effect |
|
Definition
|
|
Term
| class Ic antiarrythmics phys effect |
|
Definition
| no effect on AP but slow condn but -> arrhythm |
|
|
Term
| class II antiarrythmics phys effect |
|
Definition
BB: dn cAMP, dn CA current.
Suppress abnl pacemakers (phase 4) esp AV node |
|
|
Term
| class III antiarrythmics phys effect |
|
Definition
up AP durn, up refr period, up QT
check LFT, PFT, TFT |
|
|
Term
| class IV antiarrythmics phys effect |
|
Definition
| AV node: slow condn, up refr, up PR |
|
|
Term
| class I antiarrythmics phys effect |
|
Definition
dn condn (esp in depol cells)
slow phase 4 depol (state dependent)
up threshold for firing in abnl pacemakers |
|
|
