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trueger
MB 1
47
Other
Not Applicable
05/25/2006

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Cards

Term
southern blot
Definition
DNA blot
Term
northern blot
Definition
RNA blot
Term
western blot
Definition
protein blot
Term
what MB does mt do?
Definition
fatty acid ox
acetyl a prodn
krebs cycle
ETC
Term
what MB is in cytoplasm?
Definition
glycolysis
fatty acid synth
HMP shunt
protein synth (RER)
steroid synth (SER)
Term
what MB is in cytoplasm & mt?
Definition
gluconeogensis
urea cycle
heme synth
Term
DNA blot
Definition
southern blot
Term
RNA blot
Definition
northern blot
Term
protein blot
Definition
western blot
Term
fatty acid ox
acetyl a prodn
krebs cycle
ETC
Definition
what MB does mt do?
Term
glycolysis
fatty acid synth
HMP shunt
protein synth (RER)
steroid synth (SER)
Definition
what MB is in cytoplasm?
Term
gluconeogensis
urea cycle
heme synth
Definition
what MB is in cytoplasm & mt?
Term
ATP props
Definition
2 phosphoanhydride bonds @
7kcal/mol each
Term
output of aerobic MB
Definition
38 ATP via malate shuttle
36 ATP via G3P shuttle
Term
output of glycolysis
Definition
2 ATP
Term
S-adenosyl methionine
Definition
S-adenosyl methionine
regen reqs b12
Term
transfers methyl groups to stuff
Definition
ATP + methionine
transfers methyl groups to stuff
regen reqs b12
Term
regen reqs b12
Definition
SAM
Term
what -> GABA?
Definition
glutamate
reqs B6
Term
glutamate -> what sign mol?
Definition
GABA
reqs B6
Term
what reqs B6?
Definition
glu->GABA
Term
rate lim step of glycol?
Definition
fru-6-p -> fru 1,6,bisp via PFK 1
Term
1,3 BPG -> 2,3 BPG via
Definition
bisphosphoglycerate mutase
Term
NAD+ used in
Definition
catab to carry reducing equivs as NADH
Term
NADPH used in
Definition
anabol (ster & FA synth)
reducing equivs

anab processes
resp burst
p450

Term
rep burst
Definition
NADPH (-> O2 rad)
superoxide dismutase(H2O2)
myeloperoxidase(HClO.)

catalase(conv H2O2)
glutathione reductase(regen glutath)
G6PD(regen NADPH)

Term
hexokinase
Definition
found throughout body
feedback inh by G6P
Term
glucokinase
Definition
found mainly in liver
higher Km & Vmax
phosph excess glucose to sequester as G6P (in liver)
not FB inh
Term
found throughout body
feedback inh by G6P
Definition
hexokinase
Term
found mainly in liver
higher Km & Vmax
phosph excess glucose to sequester as G6P (in liver)
Definition
glucokinase
Term
regulated steps in gly
Definition
glu->G6P
hexokin/glucokin
inh: G6P (h)

F6P->F1,6P
pfk1
inh:atp&citrate
act:AMP,F2,6

PEP->Pyr
PK
inh:ATP,ala
act:F1,6

pyr->acCoA
pyrDH
inh:ATP,nadh,acCoA

Term
pfk1
Definition
F6P->F1,6P

inh:atp&citrate
act:AMP,F2,6

Term
pyr kinase
Definition
PEP->pyr

inh:ATP,ala
act:F1,6

Term
pyr DH
Definition
pyr->acCoa

inh:ATP,NADH,acCoA

Term
glycolytic enz def
Definition
hemolytic anemia
RBCs=no mt

hexokin,GPisom,aldolase, triphos isom, phos gly kin, enolase, pyr kin

Term
pyr DH complex
Definition
3 enzymes, 5 cofactors
pyr + NAD + CoA -> AcCoA + CO2 + NADH
actd by exer: up NAD, ADP, Ca
Term
pyr DH cofactors
Definition
pyrophosphate (B1)
FAD (b2)
NAD(b3)
CoA(B5, pantothenate)
lipoic acid
Term
pyr DH def
Definition
backup of pyr & ala -> lac acidosis
seen in B1 def (alcoholics)
neuro defs
tx:up ketogenic nutrs (high fat, lys & leu)
Term
pure ketogenic aas
Definition
lys & leu
Term
ala role in MB
Definition
carries amino groups from mm to liver
Term
carries amino groups from mm to liver
Definition
ala role in MB
Term
how many atp needed to go pyr ->glu?
Definition
6atp
Term
what can pyr become?
Definition
alanine (ALT)
oxaloacetate (CO2 + ATP, via PC)
AcCoA (PDH)
lac (LDH, NADH-NAD)
Term
why go pyr -> oxaloacetate?
Definition
1) repl TCA cycle
2)gluconeogen
Term
cori cycle
Definition
mm: makes lac -> liver
liver: lac -> pur (LDH)
pyr-> glu (6ATP)
send back to mm
Term
TCA products
Definition
3NADH, 1 FADH2, 2 CO2, 1 GTP =
12 ATP/AcCoA
x2/glu
Term
a ketoglutarate reqs
Definition
same as PDH
b1,b2,b3,b5, lipoic acid
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