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travel medicine
GI
51
Medical
Graduate
09/23/2010

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Cards

Term
what is the leading cause of death in travelers?
Definition
heart disease
Term
what is the scientific name for bedbugs?
Definition
cimex lectularius
Term
how is diarrhea defined?
Definition
loose motions
Term
what pathogen is responsible for most cases of traveler's diarrhea?
Definition
ETEC
Term
how does ETEC cause diarrhea?
Definition
through its heat stabile and heat labile toxins
Term
how is ETEC transmitted?
Definition
feces, fingers, flies, fomites and food
Term
what is the best way to sterilize water?
Definition
boil it for 1 min
Term
is ice in other countries possibly dangerous?
Definition
yes
Term
what is the BRAT diet for traveler's diarrhea?
Definition
banana, rice, apple sauce, toast/tortilla
Term
how do pts with hep A present?
Definition
jaundice, dark urine, clay-colored stool, nausea, malaise, fever, itchiness
Term
what bodily substance has the highest level of hep A?
Definition
feces
Term
what does hep E present like?
Definition
hep A. hep E is often a dx of exclusion if hep A has been r/o
Term
what animal is associated with hep E?
Definition
pigs
Term
who is a hep E prognosis particularly bad for?
Definition
pregnant women/fetus
Term
what is another name for typhoid fever?
Definition
enteric fever
Term
how does disease due to typhoid and malaria compare?
Definition
malaria: sharp spikes in fever w/intermittent return to normal, typhoid: slow progression to fever
Term
what did alex the great die of?
Definition
typhoid
Term
**how can typhoid affect HR?**
Definition
typhoid can produce relative bradycardia. usually if a pt has a fever, the heart rate increases proportionately (1 degree rise in body temperature then heart rate will rise 10 bpm) - but w/fever due to typhoid the HR does not increase proportionately
Term
what does the name typhoid mean?
Definition
"cloudy" - referring to the change in mental status
Term
can typhoid cause GI ulcers?
Definition
yes, in peyer's patches which can perforate and bleed = peritonitis
Term
what are rose spots?
Definition
blanching macular rashes associated with typhoid fever
Term
what is the organism responsible for typhoid fever? where can it be found in the animal kingdom?
Definition
salmonella typhi - found on reptiles+bats
Term
what is the best way to test for salmonella typhi?
Definition
bloodwork
Term
other than rose spots and fever, how do typhoid fever pts often present?
Definition
abdominal pain, coated tongue, altered bowel habits, hepatosplenomegaly, GI bleed, muttering delirium, and coma vigil
Term
what drugs are used against salmonella typhi?
Definition
cephalosporin, azithromycin, and quinolones
Term
what were the 3 main diseases that classically needed to be reported to the WHO?
Definition
cholera, plague, and yellow fever
Term
how does vibrio cholera appear?
Definition
"comma-shaped"
Term
what is the cause of death in cholera?
Definition
serial dehydration
Term
what is the most important tx for cholera pts?
Definition
fluids and electrolytes
Term
what characterizes the stools associated with cholera?
Definition
*rice water
Term
what is one of the most important public heath interventions of the last century?
Definition
ORT - oral rehydration therapy
Term
what does vibrio vulnificus cause? what is it commonly due to?
Definition
causes: necrotizing fascitis, sepsis. due to: contaminated seafood
Term
are snake bites considered tropical disease now?
Definition
yes
Term
how is malaria diagnosed?
Definition
*peripheral blood smear*
Term
can malaria cause jaundice?
Definition
yes
Term
if a person doesn't travel, but lives w/in 5 mi of an airport, can they still get malaria?
Definition
yes
Term
what is the lifecycle for plasmodium (malaria)?
Definition
female anophele mosquito is inoculated, it injects them into a human host, the sporozoites go to the liver and infect RBCs. gametocytes exit the RBCs and are then picked up by another mosquito. reproduction is asexual in humans, sexual in mosquitoes.
Term
what is rosesetting?
Definition
when plasmodium-infected RBCs are clumped together
Term
what are some humoral complications of malaria?
Definition
cerebral malaria, splenic infarction, or hematoma
Term
what is severe malaria?
Definition
more than 5% RBCs infected
Term
how can malaria present other than a fever?
Definition
severe anemia and nephrotic syndrome. severe malaria: jaundice, pulmonary edema, gingival bleeding, DIC, ARDS, seizure, and hemorrhage
Term
what drug is used for relapsing malaria (vivax/ovale)?
Definition
primaquine
Term
what is the the *classic presentation of dengue fever?
Definition
bright red rash w/islands of white. thrombocytopenia, shock, retro-orbital pain, and depression
Term
what is the vector for dengue fever?
Definition
mosquito
Term
how is dengue tested for?
Definition
ELISA, PCR
Term
what is the halstead hypothesis?
Definition
for dengue fever, there are 4 circulating types. a pregnant mother becomes infected, develops IgG, passes it on to her child, but then her child becomes infected by another type of dengue-causing pathogen
Term
what is the most common viral infection in the world?
Definition
dengue fever
Term
what is the morphology of the ebola virus?
Definition
"thread-like"
Term
why does ebola not spread easily?
Definition
it kills 90% of its hosts
Term
what characterizes yellow fever?
Definition
vaccine requirement if visiting countries in africa/s. america (endemic areas). the vaccine is good for 10 yrs. it is a mosquito borne infection. it is associated with coffee ground vomit and has the same vector as dengue fever *aedes aegypti.
Term
ssss
Definition
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