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Transposons
Key Terms
17
Biology
Undergraduate 2
06/10/2010

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Term
Alu element
Definition
common type of SINE, about 11% of human genome, important tool in human population genetics and primate comparative genomics
Term
autonomous element
Definition
encode transposase and end sequences required to mobilize element (McClintock's Ac element in maize)
Term
conservative site-specific recombination
Definition
segment of DNA moves between specific sequences recognized as DNA recombination sites using cognate recombinase, lack of high-energy cofactor
Term
cut-and-paste transposition
Definition
element moved directly to new location
Term
excisionase (Xis)
Definition
bacteriophage encoded protein required for bacteriophage to excise from the chromosome
Term
insertion sequence
Definition
simplest mobile element in bacteria, comprised of transposase-encoding gene flanked by DNA sequences on which transposase protein acts to move element
Term
integrase
Definition
conservative site-specific recombinase that integrates bacteriophage lambda into the host chromosome at a specific position
Term
inverted repeat
Definition
palindromes
Term
mobile genetic element
Definition
what it sounds like...
Term
non-autonomous element
Definition
end sequence recognized by transposase, but do not encode transposase, can be mobilized by providing transposase in trans from an alternate source
Term
recombinase
Definition
acts at specific site within termination region, converting dimer into two separate daughter chromosomes
Term
replicative transposition
Definition
process where transposases use extensive DNA replication to leave one copy of element behind
Term
resolvase
Definition
allow separation of donor and target molecules in replicative transposition
Term
transposable element
Definition
what it sounds like...
Term
transposase
Definition
self-encoding recombination enzyme that binds to the ends of a transposon and catalyzes the movement of transposon to another part of genome
Term
transposition
Definition
process in which a discrete DNA entity can move between DNA sites that lack homology using a self-encoded recombination protein
Term
transposon
Definition
sequences of DNA that can move around to different positions within the genome of a single cell
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