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Topic 15
DNA Packaging in Eucaryotes
8
Biology
Undergraduate 1
04/14/2012

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Term
Chromatin
Definition
DNA combined with histone proteins.
Term
Euchromatin
Definition
Unfolded, being utilized.
Term
Heterochromatin
Definition
Highly folded, not being utilized.
Term
Packaging of DNA - Stage 1
Definition
Negatively charged DNA wraps around positively charged histone forming core particle known as "10nm fiber" or "beads on a string".
Term
Nucleosome
Definition
Core Particle + linker DNA.
Term
Packaging of DNA - Stage 2
Definition
"10nm fiber" coils and forms "30nm fiber". Loops are called solenoids.
Term
Packaging of DNA - Stage 3
Definition
"30nm fiber" attaches to scaffold protein forming a series of looped domains.
Term
Packaging of DNA - Stage 4
Definition
"300nm fiber" supercoils to form chromosomes.
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