Term
| 3 steps in the top-bottom system approach |
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Definition
1. behavior
2. network activity
3. cellular/molecular |
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Term
| 3 steps in the bottom-top LTP approach |
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Definition
1. cellular/molecules
2. network activity
3. behavior |
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Term
| 6 shared properties of LTP & learned behaviors |
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Definition
1. experience-dependent
2. input specific
3. rapid induction
4. long-lasting
5. stimulus threshold required
6. associative or non-associative |
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Term
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Definition
| input unable to undergo LTP by itself |
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Term
|
Definition
| input able to undergo LTP by itself |
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Term
| 2 types of activation that can happen for postsynaptic LTP to occur |
|
Definition
1. NMDAR activation
2. VDCC activation |
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Term
| 3 phases that characterize classic LTP |
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Definition
1. induction
2. expression
3. maintenance |
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Term
| 3 postsynaptic mechanisms to relieve the magnesium block of the NMDAR |
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Definition
1. large summation of temporally & spatially converging AMPAR EPSPs
2. dendritic backpropagation of somatic action potentials
3. local generation of dendritic action potentials |
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Term
| Bienenstock, Cooper, & Munro Model (BCM Model - 1982) |
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Definition
| explains how calcium signal leads to both LTP & LTD |
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Term
| spike timing dependent plasticity (STDP) |
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Definition
| a temporally asymmetric form of Hebbian learning induced by tight temporal relations between the spikes of pre- and postsynaptic neurons |
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