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Top 300 Drugs - Spring 2014 Set 1
For Philadelphia College of Pharmacy Case
15
Pharmacology
Undergraduate 4
01/13/2014

Additional Pharmacology Flashcards

 


 

Cards

Term

Template Card 

IGNORE

Definition

BRAND/GENERIC:

CLASS:

INDICATION: 

MOA:

DOSAGE:

Term
IMIQUIMOD
Definition

BRAND/GENERIC: Zyclara

CLASS: Immune Response Modifer

INDICATION: Actinic Keratosis, Condyloma acuminatum, external, Superficial basal cell carcinoma, on trunk, neck, or extremities

MOA: Unknown

DOSAGE: Topical Cream

Term
COLCHICINE
Definition

BRAND/GENERIC: Colcyrs 

CLASS: Antigout 

INDICATION: Gout, acute & prophylaxis, Familial Mediterranean fever

MOA: Alkaloid. Interupts the cycle of monosodium urate crystals deposition in joints and tissues. Inhibits urate crystals deposition

DOSAGE: Tablet

Term
VARENICLINE
Definition

BRAND/GENERIC: Chantix

CLASS: Smoking Cessation Agent

INDICATION: Smoking Cessation

MOA: Binds with high affinity & selectivity to α4β2 neuronal nicotinic acetylcholine receptors producing agonist activity and preventing nicotine binding to receptors

DOSAGE: oral tablet 

Term
TRAVOPROST
Definition

BRAND/GENERIC: Travatan Z

CLASS: Prostaglandin Antiglaucoma Agent 

INDICATION: Ocular hypertension, open-angle glaucoma

MOA: a Prostaglandin F 2-alpha analog, increases outflow of aqueous humor. 

DOSAGE: Ophthalmic solution

Term
LATANOPROST
Definition

BRAND/GENERIC: Xalatan

CLASS: Ophthalmic Solution

INDICATION: Oculat Hypertension

MOA: A prostoglandin F2-alpha analog, reduces intraocular pressure by increasing the outflow of aqueous humor

DOSAGE: Ophthalmic solution

Term
ALLOPURINOL
Definition

BRAND/GENERIC: Zyloprim

CLASS: Xanthine Oxidase Inhibitor, Antigout 

INDICATION: Gout, mild moderate severe; Hyperuricemia, tumor lysis syndrome

MOA: Decrease production of uric aci by inhibiting the action of xanthine oxidase and increase reutilization of hypoxantine and xanthine for nucleodtide and nucliec acid synthesis via HGPRTase. Decreases uric acid concentration in serum and urine

DOSAGE: tablet

Term
ADAPALENE
Definition

BRAND/GENERIC: Differin

CLASS: Retinoid Anticane

INDICATION: Acne vulgaris

MOA: Exhibits retinoic acid-like activity, reducing important features of pathology of acne vulgaris by normalizing the differention of follicular epithelia cells and keratinization to prevent microcomedone formation. Enhance keratinocyte differentiation without hyperplasia or irritation. Dreases foramtion of comedones and inflammatory/noninflammatory acne lesions 

DOSAGE: Cream; Gel/Jelly; Lotion

Term
BIMATOPROST
Definition

BRAND/GENERIC: Lumigan; Latisse 

CLASS: Prostaglandin, Antiglaucome Agent, Cosmetic Agent for Eyelas Growth

INDICATION: Ocular hperentsion and open angle glaucoma; hypotrichosis of eyelases

MOA: A synthetic prostaglandin analog. Lowers intraocular pressure by increasing outflow of aqueous humor through trabecular meshwork and uveoscleral drainage systems. May work by increasing duration and precentage of hairs in anagen or growth phase

DOSAGE: Ophthalmic Solution

Term
POTASSIUM CHLORIDE
Definition

BRAND/GENERIC: Klor-con

CLASS: Electrolyte, Potassium 

INDICATION: Hypokalemia, adult & prophylaxis

MOA: An electrolyte required for maintence of excitatory properties of neuromuscular tissues and resting membrane potentia of cells related to potassium concentration. vary directly with ration of intracellular to extracellular K levels

DOSAGE: Oral Capsule, ER; Oral powder; Oral solution; Oral Tab, ER

Term
Prenatal Vitamin
Definition

BRAND/GENERIC: Various

CLASS: Vitamin Supplement

INDICATION: Diet Supplementation during pregnancy

MOA: Provide vitamin & mineral supplementation throughout pregnancy & during the postnatal period for both lactating & nonlactating mother. Useful to improve nutritional status prior to conception

DOSAGE: Oral Tablet 

Term
FERROUS SULFATE
Definition

BRAND/GENERIC: Feosol

CLASS: Minarl

INDICATION: Anemia, iron deficiency, treatment & prevention

MOA: Iron is a component in hemoglobin and required for synthesis of red bloo cells. Absense of iron results in small heomoglobin molecules and microcytic anemia

DOSAGE: Oral tab; Elixar, oral; Liquid, oral & oral drops

Term
FOLIC ACID
Definition

BRAND/GENERIC: Folancin-800

CLASS: Essential B Vitamin

INDICATION: Folic acid deficiency; pregnancy, prophylaxis

MOA: Folic acid is required for the conversion of deoxyuridylate to thymidylate, which is a rate of limiting step in DNA synthesis which presents clinically as macrocytic aneima when red blood cells are unable to extrude their nucleus 

DOSAGE: Oral tablet 

Term
CYANOCOBALAMIN
Definition

BRAND/GENERIC: Cobolin-M

CLASS: Essential B Vitamin (B12)

INDICATION: Cobalamin deficiency: normal absorption & malabsorption

MOA: B12 required to synthesis of amino acid methionine from homocyteine. Methionine is needed for DNA synthesis. B12 deficiency results in decrease DNA synthesis which presents as macrocytic anemia

DOSAGE: Injection solution; Intramuscular solution; Mucous Membrane Lozenge/Troche; Oral tablet; Oral tab ER; Sublingual tablet

Term
BRIMONIDINE
Definition

BRAND/GENERIC: Alphagan P

CLASS: α2-Adrenergic Agonist; Antiglaucoma Agent

INDICATION: Oculat Hyperentsion; Open-angle glaucoma

MOA: a relatively selective α2-adrenergic agonist reduces aqueous humor production and increase uveoscleral outflow. 

DOSAGE: Ophthalmic Solution

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