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Toledo PT Endocrine System
Toledo PT Endocrine System
50
Science
Professional
09/29/2009

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Term
3 classes of hormones
Definition
amine, peptide & protein, steroid
Term
Amine hormones
Definition
Thyroid , Catecholamines, Dopamine
Term
What category do the majority of hormones belong to?
Definition
Peptide hormones
Term
At what cellular structure do nonactive prohormones become activated?
Definition
Golgi Apparatus
Term
Steroid Hormones
Definition
Cortisol, Aldosterone, Testosterone, Estradiol, 1,25- dihydroxyvitamin D
Term
What endocrine organs secrete steroid hormones?
Definition
Adrenal Cortex, Gonads
Term
Hormones from Adrenal Cortex
Definition
Mineralocorticoid: Aldosterone, Glucocorticoids: Cortisol, Corticosterone, Androgens: Dehydroepiandrosterone (DHEA), Androstenedione.
Term
Levels of Adrenal Cortex top->bottom
Definition
Zona glomerulosa, fasciculata, reticularis.
Term
Hormone Secreted by Zona glomerulosa
Definition
Aldosterone
Term
Hormone secreted by Zona Fasciculata and Reticularis
Definition
Cortisol and Androgens
Term
How is are steroid hormones transported in the blood?
Definition
Largely bound to albumin, some are dissolved in plasma as free hormones.
Term
How are peptide hormones transported in the blood?
Definition
largely dissolved in plasma
Term
4 methods for clearance of hormones
Definition
Excreted in urine or feces, inactivated by metabolism, activated by metabolism, bind to receptor and produce a cellular response.
Term
Regulation of hormone receptors
Definition
Down-regulation with high concentration of hormone, Up-regulation with low concentration of hormone.
Term
Thyroid example of Permissive role of hormone
Definition
thyroid hormone can help up regulate epinephrine receptors to achieve epinephrine breakdown that would normally be unattainable without thyroid hormone.
Term
T/F Epinephrine is capable of high levels of Fatty Acid breakdown without thyroid hormone present.
Definition
False. The permissive role of thyroid hormone with epinephrine allows high levels of FFA breakdown to occur.
Term
T/F. Peptide hormones and other water soluble hormones interact with receptors on the plasma membrane and are involved in rapid cellular response.
Definition
Trueskies
Term
T/F. Steroid Hormones interact with reeceptors located on plasma membrane and are involved in rapid response.
Definition
False. Steroid hormones interact with intracellular receptors on nuclear membrane, affect gene activity with slower physiological response.
Term
3 things capable of altering rate of hormone secretion
Definition
Ions/nutrients, Neurotransmitters, Hormones.
Term
Primary Hyposecretion
Definition
Partial destruction of gland, decreased synthesis ofhormone due to lack of necessary enzyme, dietary deficiency of iodine.
Term
Secondary Hyposecretion
Definition
No damage on gland itself, but lack of its tropic hormones.
Term
Will Primary hyposecretion respond to tropic hormone administration?
Definition
No. The gland has been destroyed or is intrinsically incapable of producing the hormone no matter how much it is stimulated to do so.
Term
Will secondary hyposecretion respond to tropic hormone?
Definition
Yes. Secondary hyposecretion occurs as a result of tropic hormone deficiency. Therefore, if the hormone is supplied by injection then the gland should respond to the tropic hormone and normal function would continue.
Term
Primary Hypersecretion
Definition
the gland secretes too much hormone
Term
Secondary Hypersecretion
Definition
The gland is stimultaed by its tropic hormone to produce too much hormone.
Term
What is the common cause of hypersecretion?
Definition
The presence of endocrine cell tumor.
Term
Will there be high or low levels of tropic hormone in primary hypersecretion?
Definition
Low
Term
Will there be high or low levels of tropic hormone in secondary hypersecretion?
Definition
High.
Term
Hyporesponsiveness
Definition
REduced hormone receptors on target cells. abnormality in intracellular signaling proteins. lack of enzyme in activating hormone product. In general hormone in plasma is elevated in the presence of hyporesponsiveness.
Term
Does the Anterior Pituitary Gland have direct neural connection with hypothalamus?
Definition
Nope
Term
What kind of connection does the posterior pituitary have with the hypothalamus?
Definition
Neural connection
Term
What function does the infundibulum have in teh hypothalamo-pituitary gland?
Definition
It connects the pituitary gland and the hypothalamus.
Term
Hypophysiotropic Hormones from Hypothalamus
Definition
Coricotropin-releasing Hormone, Thyrotropin-releasing hormone, Gonadotropin-releasing hormone, growth hormone-releasing hormone, growth hormone release-inhibiting hormone, prolactin-releasing hormone, prolactin release-inhibiting hormone(dopamine)
Term
T/F Dopamine serves as the major prolactin release-inhibiting hormone.
Definition
True
Term
CRH function
Definition
stimulates secretino of ACTH
Term
TRH function
Definition
stimulates secretion of TSH
Term
GHRH function
Definition
stimulates secretino of GH
Term
Somatostatin functio
Definition
inhibits secretino of GH
Term
GnRH
Definition
Stimulates secretino of LH and FSH
Term
Dopamine
Definition
inhibits secretin of prolactin
Term
Hormones from Anterior Lobe
Definition
ACTH, TSH, LH, FSH, PRL, GH
Term
ACTH function
Definition
stimulates adrenal gland
Term
TSH function
Definition
stimulates thyroid gland
Term
LH function
Definition
testes and ovary are target cells, control of reproductive function.
Term
FSH function
Definition
testes and ovary are targe cells, control of reproductive function.
Term
PRL function
Definition
targets mammary gland, stimulates mammary gland development and milk production.
Term
GH function
Definition
facilitate growth, affects fat, protein, and Carbohydrate metabolism
Term
T/F Posterior lobe of pituitary produces hormone?
Definition
False. It only stores hormones.
Term
Oxytosin fucntion
Definition
stimuation of milk ejection, stimulation of uterine smooth muscle contraction at birth, extablishment of maternal behavior: nursing baby.
Term
Antidiuretic Hormone (ADH): Vasopressin
Definition
this hormone conserves body water by reducing loss of water in urine.
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