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Thyrpoid drigs for pharm
test 3
20
Aerospace Engineering
1st Grade
04/21/2014

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Cards

Term
TOC for hypothyroidism
Definition
Levothyroxine (T4)
Term
Tx for myxedema coma
Definition
IV used levothyroxine
Term
Dose of levothyroxine in adults and elderly
Definition
100-125mcg QD in adults 50-100 in elderly
Term
How do you assess for steady state?
Definition
TSH and T4 levels. T3 is too short acting to be measures
Term
What is the halflife of Levothyroxine?
Definition
1 week
Term
What is the DOC for supressing thyroid nodules, diffuse goiter and some cancers?
Definition
Levothyroxine (T4)
Term
Why should levothyroxine be taken on an empty stomach and without digestion altering drugs
Definition
Drugs like PPIs and food can alter absorption.
Term
What drugs effects can be increased by Levothyroxine
Definition
TCAS and Warfarin
Term
Why is Leothyronin (T3) rarely used
Definition
Its rare to need just T3. It also can't be measured bc T3 It doesn’t make t4
Term
What is the name of the fixed ratio mixture of T4 and T3
Definition
Liotrix
Term
What is the name of the Synthetic form of TRH called
Definition
Protirelin
Term
What is the name of synthetic TSH given IV
Definition
Thyrogen
Term
What is the treatment for Thyroid storm
Definition
Beta blockers and CCB
Term
Thiorea drugs are
Who must avoid thiourea drugs
Definition
PTU (DOC in pregnancy) and Methimazole
sulfa allergies
Term
ADRS of thiorea drugs
Definition
Rash, hepatotoxicity, agranulocyotisis
Term
Which thiorea drug has longer half life
Definition
Methimazole is longer, so its taken QD.PTU is 75 min, so its taken TID
Term
What is the category and Half life of RAI 131
Definition
Cat X. HL: 5days
Term
ADR of RAI 131
Definition
Hypothyroidism, metallic taste, Nausea, Swollen Salivary Glands
Term
Beta blockers and CCB can be used to treat the symptoms of what?
Definition
Hyperthyroidism (Tachycardia, HTN)
Term
What is the test for Adrenal Insufficiency
Definition
Adrenal Corticotropin Hormone (ACTH) given via injection and then levels are measured to check for reuptake.
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