Term
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Definition
1. located in the anterior part of the neck
2. controls the rate of body metabolism and growth
3. secretes
a. tyroxine (T4)-metabolism
b. triiodothyronine (T3)-metabolism
c. thyrocalcitionin- calcium deposit in bones |
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Term
| Levothyroxine (Synthroid T4) |
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Definition
| is a synthetic (man-made) version of the principle thyroid hormone, thyroxine (T4) that is made and released by the thyroid gland. Levothyroxine is approved to treat hypothyroidism and to suppress thyroid hormone release in the management of cancerous thyroid nodules and growth of goiters. administered in small amounts 0.1 to 0.2 mg/day |
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Term
| Liothryonine (Cytomel- T3) |
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Definition
| is used to treat hypothyroidism (low production of thyroid hormone) in adults and children. Prolonged hypothyroidism can result in a condition called myexoedema in which patients develop swollen lips, thickened nose, and unusual deposits of material in the skin that are dry and waxy. These deposits also may appear in body tissues other than the skin. Liothyronine also is used in a test of the thyroid gland to determine if the thyroid is functioning normally. |
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Term
| Liotrix (combination of T3 and T4) |
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Definition
is used to treat an underactive thyroid (hypothyroidism). It replaces or provides more of a certain natural substance (thyroid hormone) that is normally produced by the thyroid gland.
12.5 mcgT3 and 50 mcgT4 a ration of 1:4. |
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Term
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Definition
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Term
| Affects of Levothyroxine, Liothyronine, Liotrix |
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Definition
| affects the metabolic rate, cardiac output, protein synthesis and glycogen utilization |
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Term
| Drug interactions of Levothyroxine, Liothyronine, Liotrix |
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Definition
| increase action of anticoagulants, decreases serum diogxin levels, strengthens or increases affects of antidepressants, increase blood glucose in diabetics |
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Term
| Signs of Hypothyroidism (thyroid levels to low) |
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Definition
| cold intolerance, depression, edema, hair loss, constipation, lethargy, anorexia, myxedema |
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Term
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Definition
| A disease caused by decreased activity of the thyroid gland in adults and characterized by dry skin, swellings around the lips and nose, mental deterioration, and a subnormal basal metabolic rate. |
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Term
| Signs of Hyperthyroidism (thyroid levels to high) |
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Definition
* Difficulty concentrating
* Fatigue
* Frequent bowel movements
* Goiter (visibly enlarged thyroid gland) or thyroid nodules
* Heat intolerance
* Increased appetite
* Increased sweating
* Irregular menstrual periods in women
* Nervousness
* Restlessness
* Weight loss (rarely, weight gain) |
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Term
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Definition
| results from untreated hyperthyroidism. It is usually brought on by a stress such as trauma or infection. Complications include congestive heart failure and pulmonary edema can develop rapidly and lead to death.This is an emergency condition. Call 911 or another emergency number if you have hyperthyroidism and experience symptoms of thyroid storm. Symptoms are severe and may include: Agitation, Change in alertness (consciousness), Confusion, Diarrhea, Fever, pounding heart (tachycardia), Restlessness, Shaking, Sweating |
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Term
| Interventions for thyroid medications |
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Definition
-thyroid pill should be taken before 9 am
-watch dosages of different drugs
-avoid strawberries, peaches, pears, cabbage, cauliflower, radishes, peas, leafy greens and soy beans if you are having trouble regulating
-client should wear alert bracelet
-don't change brands
-avoid over the counter drugs unless you check with your physician
-know signs of adverse effects |
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Term
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Definition
| to stop production of hormone gland, resulting in hypothyroidism and patient must begin thyroid replacement. |
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Term
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Definition
| reverses hyperthyroidism requires an average of 6 weeks to lower T4 levels to normal and is often given before radioactive iodine treatment. can be taken once per day |
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Term
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Definition
*reverses hyperthyroidism must be taken two to three times per day
*used to treat thyroid storm or toxicosis
*inhibits process necessary to make precursors of T3 and T4
*does not effect release of thyroid already stored in the gland
*used for prep before surgery or I131 treatment |
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Term
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Definition
| is administered orally as sodium 131-I in solution or a capsule. The radioiodine is rapidly incorporated into the thyroid, and its beta-emissions result in extensive local tissue damage. The net effect is destruction of thyroid function over a period of 6 to 18 weeks. |
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Term
| Thyroid hormone replacements available include |
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Definition
*natural- (not used often) derived from cattle and hogs
*synthetic-(most commonly used today)
1. Levothyroxine (Synthroid)T4
2. Liothyronine (Cytomel) T3
3. Liotrix combination of T3 and T4 |
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Term
| Thyroid hormone replacement uses |
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Definition
| *used for clients who do not have sufficient thyroid hormone production |
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Term
| Thyroid hormone replacement action |
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Definition
| * affects metabolic rate, cardiac output, protein synthesis and glycogen utilization |
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Term
| Side effects and adverse effects when thyroid hormone levels are too high |
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Definition
*CNS- nervousness
*CV- tachycardia, angina, hypertension, dysrhytmia
*GI- nausea, diarrhea, changes in cramps
*Other- sweating, menstrual changes, heat intolerance, fever
*thyroid storm |
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Term
| Treatment of thyroid storm |
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Definition
| give anti-thyroid medication, beta blockers and steroids, IV fluids and anti-biotic |
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Term
| Nursing Knowledge/Process for Thyroid replacement hormones |
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Definition
*client to take in the morning before 9 am, same time every day
*watch dosages of other drugs
*client should avoid if having trouble regulating; strawberries, peaches, cabbage, cauliflower, radishes, peas, leafy greens, soy beans
*client should where a medic alert bracelet
*client should not change brands
*client should avoid OTC drugs unless y checked with Dr
*teach signs of adverse effects |
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Term
| Side effects of Anti-thyroid drugs |
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Definition
*may cause liver and bone marrow toxcity
*Hematologic
1. agranulocytosis-drops white blood cell count (normal 6000-11,000)
2.leukopenia-white blood cell drops below 500
3. thrombocytopenia-level of platelets drop for blod clotting
4. hypoprothrombinemia-prothrombin drops which is needed for clotting
5. lymphadenopathy- abnormalities in lymph system
*CNS-vertigo, H/A, paresthesia(tingling),fever
*GI- N/V, diarrhea, jaundice, hepatitis
*Other- rash, hives, alopecia(hair loss), hyperpigmentation
*Musculoskeletal- nocturnal leg cramps |
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Term
| Nursing Process and Interventions for Anti-thyroid Meds |
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Definition
*monitor vital signs
*give with food for GI upset
*give at the same time each day to maintain blood consistency
*never stop medication
*may have interactions with iodine preparations
*should never be give after expectorant or strong iodine solution
* foods high in iodine should be avoided
* |
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