Term
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Definition
A new focal neurological deficit lasting for more than 24 hours and presumed to be vascular in origin. |
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Term
What are the categories of stroke and what is an example of each? |
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Definition
Ischemic stroke (cerebral infarction) Hemorrhagic stroke (intracerebral hemorrhage) |
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Term
| List the causes of epidemiology of ischemic strokes and at what percentage they occur. |
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Definition
Atherosclerotic (large vessel disease) - 20% Small vessel disease - 25% Cardiogenic embolism - 20% Cryptogenic - 30% Other causes - 5% |
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Term
| What are non-modifiable risk factors of stroke? |
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Definition
Age - risk increases with increasing age Gender - males > females Race - blacks>hispanic>white>asians Ethnicity Genetics |
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Term
| What are the risk factors for a hemorrhagic stroke? |
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Definition
HTN smoking (2-4x increased risk) drug abuse (cocaine, amphetamines, alcohol) arteriovenous malformations cranial tumors anticoagulation trauma
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Term
| What are the risk factors for ischemic stroke? |
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Definition
non-modifiable risk factors (age, gender, race) low birth weight family history of stroke or TIA CVD (CHD, heart failure, peripheral artery disease) HTN smoking or exposure to smoking DM asymptomatic caroticd stenosis dislipidemia
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Term
| What are the risk factors for cardioembolic stroke? |
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Definition
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Term
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Definition
Population: >80yo with isolated SBP > 160mmHg Intervention: reduction of SBP with medication Comparison: Thiazide +/- ACEI vs. placebo Outcome: A 30% reduction of stroke was seen in the treatment arm compared to the placebo; note that the SBP was lowered by 10mmHg on average |
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Term
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Definition
Population: Elderly w/isolated HTN; SBP>160, DBP<90 Intervention: reduction of SBP with medication Comparison: CCB or Thiazide +/- BB vs. placebo Outcome: Syst-Eur showed a 42% reduction in stroke SHEP showed a 36% reduction in stroke |
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Definition
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