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The Neuron
The Biology of the Neuron
23
Biology
Undergraduate 2
02/08/2010

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Term
What are the four components of Neuronal Signaling?
Definition
Reception, Transmission, Signaling, and Response.
Term
What are Afferent Neurons?
Definition
Sensory neurons; Pick up stimulus via sensory receptors and Transmt this infro to interneurons, usually in CNS.
Term
What are interneurons?
Definition
Interneurons integrate the information from the afferent neurons and formulate a response.
Term
What are efferent neurons?
Definition
They carry the response signal to the muscles and glands so that a response can be carried out.
Term
What is a motor neuron?
Definition
Type of efferent neuron that carries signals to the skeletal muscle.
Term
What is the CNS?
Definition
The Central Nervous System: Brain, Spinal Cord (interneurons.)
Term
What is the PNS?
Definition
The peripheral nervous system: Afferent and efferent neurons.
Term
What is a nerve made up of?
Definition
Axons, Blood vessels and connective tissues.
Term
What part of the neuron receives signals and transmits them toward the cell body?
Definition
Dendrites
Term
What are astrocytes?
Definition
Star-shaped cells the cover the surfaces of blood vessels. They are for structural support and help maintain ion concentrations in the interstitial fluid surrounding them.
Term
What are some examples of Glial cells?
Definition
Schwann cells, Oligodendricytes and Astrocytes.
Term
Myelin sheaths have a high lipid content and serve to insulate electrical impulses. What are they formed by?
Definition
Schwann cells (PNS) and oligodendrocytes (CNS).
Term
What are the gaps that expose the axon membrane directly to extracellular fluid and speed the rate at which electrical impulses move along axons?
Definition
Nodes of Ranvier.
Term
What are some problems involving myelin?
Definition
Multiple Sclerosis. Inflammations attack and injure the myelin.
Guillain Barre Syndrome -- inflamation in peripheral nerves result in dysfunction of myelin sheath.
Term
What is a synapse?
Definition
The junction between the axon terminals of a neuron and the receiving cell (another neuron, muscle fiber, gland cell).
Term
What are the two types of synapse?
Definition
Electrical and Chemical.
Term
What is an electrical synapse?
Definition
When the axon terminal is in such close proximity to the postsynaptic cell that you form gap junctions.
Term
What is a chemical synapse?
Definition
1) Electrical impulse travels along the axon and arrives at the terminal.
2) A neurotransmitter is released.
3) A neurotransmitter diffuses across a synaptic cleft, binds to receptor on postsynaptic cell.
4) New electrical impulse is generated (if enough neurotransmitter is bound).
Term
What is true in a resting membrane potential?
Definition
The cell inside is negative, the cell outer surface is positive.
Term
When does membrane potential arise?
Definition
When there is a difference in electrical charge on the 2 sides of the membrane.
Term
What is an Oscilloscope?
Definition
A tool that records voltage inside the cell to give you the membrane potential.
Term
What is the at rest -70V membrane potential caused by?
Definition
The uneven distribution of charged particles inside and outside the cell.

1) The NA+/K+ pump.
2) The membrane is more permeable to potassium than to sodium (many more ungated potassium channels open than ungated sodium channels.)
Term
The sodium potassium pump.
Definition
3 Sodium out, 2 potassium in.
There is a higher sodium concentration outside and a higher potassium concentration inside.
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