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The Cell Cycle-Mitosis
Chapter 12 Campbell Biology-Mitosis
38
Biology
11th Grade
01/09/2011

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Term
cell division
Definition
reproduction of cells-mitosis
Term
cell cycle
Definition
life of a cell from its origin in the division of a parent cell until its own division into two (interphase, mitosis, cytokinesis)
Term
somatic cells
Definition
body cells
Term
gametes
Definition
sex cells - sperm and egg
Term
chromatin
Definition
DNA-protein complex in long, thin threads not visible under a light microscope
Term
sister chromatids
Definition
duplicated chromosomes, contain identical copies of the chromosome's DNA molecule
Term
centromere
Definition
region that joins the two sister chromatids
Term
mitosis
Definition
division of the nucleus-prophase, metaphase, anaphase, telophase
Term
cytokinesis
Definition
division of the cytoplasm
Term
meiosis
Definition
cell division that produces sex cells (sperm and egg)
Term
M phase (mitotic phase)
Definition
part of the cell cycle that includes mitosis and cytokinesis, usually shortest part
Term
interphase
Definition
90% of the cell cycle, cell growsn and copies chromosomes (contains three parts G1, S, G2)
Term
S phase
Definition
part of interphase in which the chromosomes duplicate
Term
prophase
Definition
first phase of mitosis: nuclear membrane and nucleolus disintegrate, spindle fibers form, centrosomes move to opposite poles, spindle fibers attach to kinetochores on chromosomes
Term
metaphase
Definition
chromosomes become aligned along the middle of the cell
Term
anaphase
Definition
sister chromatids pulled apart
Term
telophase
Definition
nuclear membrane and nucleolus refrom, chromosomes disperse, spindle apparatus breaks down, cleavage furrow begins to form
Term
kinetochore
Definition
region on the centromere where the spindle fibers attach in order to pull the sister chromatids apart
Term
mitotic spindle
Definition
microtubules and proteins that originate at the centrosome and attach to the chromosomes at the kinetochores
Term
asters
Definition
name given to the arrangement of microtubules from the centrosomes "stars"
Term
metaphase plate
Definition
midway between the poles of the cell where the chromosomes align
Term
cleavage furrow
Definition
shallow groove in the cell surface near the old metaphase plate; first indication that cytokinesis is going to occur
Term
cell plate
Definition
produced in plates instead of a cleavage furrow; made of vesicle contents derived from the Golgi
Term
binary fission
Definition
bacterial reproduction meaning "division in half"
Term
cell cycle control system
Definition
set of molecules in the cell that both triggers and coordinates key events in the cell cycle
Term
checkpoint
Definition
stop and go signals that regulate the cell cycle
Term
G0 Phase
Definition
nondividing state of a cell
Term
cyclin
Definition
protein in a cell that's concentration fluctuates
Term
Cdk's (cyclin dependent kinases)
Definition
molecules in constant concentration in the cell
Term
MPF-maturation promoting factor
Definition
association of cyclin with Cdk's that initiates mitosis by phophorylating a variety of proteins
Term
growth factor
Definition
protein released by body cells that stimulates other cells to divide
Term
density-dependent inhibition
Definition
phenomenon in which crowded cells stop dividing
Term
anchorage dependence
Definition
cells must be attached to a substratum in order to divide
Term
transfromation
Definition
process that converts a normal cell to a cancer cell
Term
tumor
Definition
mass of abnormal cells
Term
benign tumor
Definition
lump that remains at the original site
Term
malignant tumor
Definition
lump that becomes invasive and moves eventually impairing the function of other organs
Term
metastatis
Definition
spread of cancer cells beyond their original site
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