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Test 8
Acid Base Slides
24
Physiology
Professional
12/15/2010

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Term
ph range for life
Definition
6.8-8.0
Term
normal ph range
Definition
7.35-7.45
Term
venous blood is more acidic/alkyline that arteriole blood
Definition
acidic
Term
what decreases excitability of muscles/nerves?
Definition
more acidic
Term
what increases excitability of muscles/nerves?
Definition
less acidic
Term
how does acidosis affect kidney function (reabsorption/secretion)
Definition
kidney substitutes secretion of K+ for H+, so K+ is retained in cell and hyperkalemia results
Term
major source of H+ in body?
Definition
carbonic acid production from CO2 and H20
Term
3 places of defense against pH changes
Definition
blood lungs kidneys
Term
Henderson Hasselbach equation?
Definition
ph = pka + log (unprotonated)/(protonated)
Term
high levels of H+ does what to ventilation?
Definition
increases to decrease CO2 levels
Term
low levels of H+ does what to ventilation?
Definition
lowers it (depresses) to increase amounts of CO2 and therefore H+
Term
if PCO2 rises, what does kidney do?
Definition
secretes acid
Term
If [HCO3-]/[CO2] is < 20
Definition
acidosis
Term
If [HCO3-]/[CO2] > 20
Definition
alkylosis
Term
what is the cause of acidosis/alkalosis if CO2 levels are off?
Definition
respiratory
Term
what is the cause of acidosis/alkalosis if HCO3- is abnormal
Definition
metabolic
Term
cause of respiratory acidosis?
Definition
retnention of CO2--hypoventilation
Term
how do u compensate for respiratory acidosis?
Definition
retain HCO3- to balance out the elevated CO2
Term
causes of metabolic acidosis
Definition
diarrhea (loss of HCO3-)
diabetes, xs fat metab, ketoacidosis, exercise (lactic acid), uremic acidosis-renal failure
Term
how do u compensate for metab acidosis?
Definition
increase pulmonary function, hyperventilate, excrete acid, connserve more HCO3-
Term
causes of respiratory alkalosis:
Definition
loss of CO2 (hyperventilation)
fever
anxiety
aspirin poisoning, high alts
Term
how do u compensate for resp alk?
Definition
conserve H+ and excrete HCO3-
Term
causes of metabolic alk?
Definition
vomiting
ingestion of alk drugs
Term
compensation for metab alk?
Definition
hypoventilation (conserve CO2)
secrete less H+ and excrete more HCO3-
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