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Test 3 pharm MRS THORPE
n/a
127
Pharmacology
Undergraduate 1
06/01/2010

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Cards

Term
What are hormones?
Definition
Chemical messengers
Term
Two part of the pituitary gland
Definition
anterior and posterior
Term
9 endocrine glands of the body
Definition
overies, testies, thyroid, uterus, adrenals, kidney, breast, parathyroid and __________
Term
Two specifice drugs of the posterior pitutary
Definition
desmopressin, vasopressin
Term
Actions of vasopressin
Definition
regulates re-obsorption of water by the kidneys. Used to treat diabeties insipitus, conserve water, post-op abd. distention
Term
Diabeites insipidus is
Definition
failure of posterior pitutary to secreat vasopressin
Term
desmopressin acetatae may be givin
Definition
po, sc, intra-nasal
Term
Pt's with DI have an:
Definition
increased thirst
Term
pt's with DI are px ________. Why?
Definition
vasopressin to conserve water
Term
How can Pt avoid a/r of skin blanching
Definition
give w/ 1-2 glasses H20
Term
list 2 gonadotrophins
Definition
FSH, LH
Term
Female secondary sex char.
Definition
vagina, uterus, fallopian tubes, breat develepment
Term
Male secondary sex char.
Definition
facial hair, deep voice, body hair, body fat distrabution, muscle development
Term
Gonadotropin hormone a/r
Definition
hot flashes, ovarian enlargment, hemoperitoneum
Term
Decreased vison with gonadotrophins, what do you do
Definition
call MD
Term
somatotropic is the _____ hormone
Definition
GH
Term
Who are canadates for GH use
Definition
children with open epiphysis in the bones
Term
Base lines to doc before starting GH therapy
Definition
Ht and Wt
Term
Where are the adrenal glands located?
Definition
On top the kidneys
Term
Slucocorticoid and mineralcorticoids are collectively known as?
Definition
steroids
Term
When taking GH hormone SC monitor?
Definition
glucose tolerance
Term
Corticotrophin + cholinergic blocker =
Definition
decresed muscle function
Term
When to take thyroid meds?
Definition
AM before breakfast
Term
Take V/S every ______hrs when taking glucocorticoids.
Definition
4-8 hrs
Term
Pt's with myxedema may have increased?
Definition
cold tolerance
Term
desiccated thryoid + SSRI =
Definition
decreased effect of thyroid med.
Term
Caution when giving liothyronine to pt's with?
Definition
cardiac disease
Term
Pt. taking methimazole who develop skin rash should?
Definition
use soap sparingly
Term
Action of melphalan
Definition
cure or slow cancer, pallitive care
Term
Gastric a/r of propythiouracil
Definition
vomiting
Term
Another name for thyrotoxicosis is?
Definition
thyroid storm
Term
Characteristic symptom of thyrotoxicosis is?
Definition
AMS
Term
Cardiac a/r of Liotrix for thyrotocicosis
Definition
tachycardia
Term
Decreased WBC is called
Definition
agranuolcytosis
Term
2 hormones the thyroid secreats
Definition
T3
T4
Term
Tapazole is used to treat?
Definition
hyperthyroidism
Term
Why will you monitor a pt's glucose levels on GH?
Definition
Term
What does thyroid storm mean and what are the s/s?
Definition
Thyroidtoxicosis
s/s increased fever, extreame tachycardia, AMS
Term
Male sex hormone is?
Definition
Androgens/testosteron
Term
What is an androgen?
Definition
male hormone testosteron
Term
Tissue buildind process caused by androgens.
Definition
anabolism
Term
Failure to develop testies is called?
Definition
hypogonadism
Term
2 endogenouse female hormones are?
Definition
estrogen and progesteron
Term
Where are extrogens secreated?
Definition
ovarrian follicle
Term
Where is progesterone secreated?
Definition
corpus luteum, placenta, adrenal cortex
Term
Uses of estrogena and pregesteron?
Definition
contraception
Female: hypergonadism, osteoperosis, Males: prostate cancer, amenorrea, endometriosis
Term
Fluoxymesterone in an androgenic drug because?
Definition
it's a male hormone drug
Term
A/R of fluoxymesterone is virtilization, what is that?
Definition
When women develop male secondary sex characteristicsdue to testosteron
Term
Symptoms of verilization
Definition
deep voice, facial hair, increase muscle, body fat distrabution
Term
A/R of gosereline acetate?
Definition
sexual disfunction, breast tenderness
Term
A/R of androgen therapy is liver toxicity. S/S of hepatotoxicity are?
Definition
jaundice, electrolyte imblance, lethergy
Term
natural and synthetic gonadotrphins are collectively known as?
Definition
progestins
Term
estrogen and progesterin therapy is contraindicated in pt's with?
Definition
breast cancer
Term
Androgen therapy is used as replacemnt therapy for?
Definition
hypogonadism
Term
Is estrogen secreated by the ovarian follicle?
Definition
No
Term
The herb saw palmetto is used to treat?
Definition
BPH
Term
What is BPH?
Definition
enlarged prostate that is not cancer.
Term
testosteron and its derivatives is collectively known as?
Definition
androgens
Term
Estrogen is given IM and IV to treat?
Definition
uterin bleeding caused by hormone imbalance
Term
A/R of progesterones?
Definition
HA, migraine, dizziness, mental depression, abd. bloating
Term
Main use of oxytocin?
Definition
to produce uterine contractions
Term
Main use of a tocolytic?
Definition
prevent uterin contractions
Term
What do uterine stimulants do?
Definition
cause smooth muscle in the uterus to contract
Term
When are ergonavine and methylergonovine given?
Definition
3rd stage of labor/at delivery
Term
Effects ofoxytocin on the fetus?
Definition
bradycardia
Term
What is your role when administering oxytocin?
Definition
cont. monitor the pt
Term
Why is ergovine contraindicated in pt with HTN.
Definition
risk of stroke
Term
Oxytocin with stimulate what reflex?
Definition
milk ejection reflex
Term
Call MD is oxytocin intr-nasaly produces the a/r of?
Definition
palpitations
Term
what is a/r of methlergonovine's ergotism?
Definition
coolness, nub. and ting. of limbs
Term
When are tocolytic drugs administered?
Definition
pre-term labor
Term
a/r of magnesium sulfate (resp.)
Definition
pilmenary edema, dyspnes, pink frothy sputum
Term
oxytocin + vasopressors =
Definition
HTN
Term
Most common tocolytic med?
Definition
magnesium sulfate
Term
tocolytics are not used until what week of pregnancy?
Definition
27th
Term
Magnesium sulfate for pre-term labor is used as an?
Definition
calcium antagonist
Term
Which drug can lead to water intoxication?
Definition
oxytocin
Term
Before giving oxytocin to induce labor, what intervention do you do?
Definition
obatin health and med hx
Term
Duuring the 3rd stage of labor, oxytocin is admin?
Definition
IM
Term
Overdose of ergonovine is?
Definition
ergotism
Term
Ergonvine is contraindicated before delivery of the placenta. T or F
Definition
true
Term
Ergonovine and methylergonovine are givein during pregnancy to prevent hemorrage. T or f
Definition
true
Term
what is immunity?
Definition
ability to resist and fight invading micro-organisms
Term
Diff between cellmediated defence and anti-body mediated defense?
Definition
Cell mediated: resulting from leukocyte action, immune response
Anti-body: circulating antibodies
Term
Cell mediated defense relies on the T-?
Definition
lymphocytes
Term
What is leukcytopenia?
Definition
Absense of WBC
Term
What is thrombocytopenia?
Definition
absense of thrombocytes
Term
What are B lymphocyte?
Definition
produce circulating antibodys that act against foreign substances.
Term
What is a toxoid?
Definition
poison substances produced by bacteria
Term
What does attenuated mean?
Definition
weakened
Term
chhicken pox is?
Definition
natural active
Term
MMR is?
Definition
artificial active
Term
Rabies shot is?
Definition
passive aquired
Term
toxoid A/R?
Definition
fever, chills, muscle aches/pain, rash, lethergy, pain/tender at inj. site.
Term
What is antivenin?
Definition
passive transient protection from snake bites/spider bites.
Term
What a is rabies vaccine?
Definition
toxoide, artificial passive
Term
What are immune globulins?
Definition
solutions from human/animal blood
Term
which vaccine prevents pulminary TB?
Definition
BCG
Term
What is MMR?
Definition
measles mumps and ruebella
Term
What is natural passive immunity?
Definition
mother to child via breast milk
Term
After a live virus vaccine, wait how long before concieving?
Definition
3 months
Term
Immune globulins are solutions obtained from human and animal blood containing antibodies? T or F
Definition
True
Term
A toxoid that is attenuated and injected is called a?
Definition
vaccine
Term
why must a female past the age of puberty take the vericella vaccine with caution?
Definition
it could effect the fetus
Term
What are anti-neoplastics used for?
Definition
chemo, delay the spread of the cancer
Term
What does slow metastasis mean?
Definition
metastasis is the spreading of cancer
Term
What does palliation mean?
Definition
comfort care for cancer
Term
What is the goal of chemo?
Definition
stop cell growth, prolong life
Term
Define alkylating agents.
Definition
change cellular enviroment by directly attacking DNA
Term
Define plant alkaloids.
Definition
taken from plants, they prevent cells from dividing normally
Term
5 A/R of plant alkaloids?
Definition
BM supression, diarrhea, hair loss, leukopenia, thrombocytopenia
Term
Chemo pt is lossing hair, what do you tell them?
Definition
guy a wig
Term
Pt with thromboyctopenia recieving anti-neoplastic meds, monitor for?
Definition
blood in urine
Term
Pt on neo-plastic meds is at risk for erythema, they should wear what?
Definition
loose fitting clothing
Term
Anti-neoplastic meds may cause bone marrow depression. What lab work will you minitor?
Definition
CBC.
Term
Cancer med, melphalan is an alkylating agent so changes cells to a more alkyline enviroment. T or F
Definition
True
Term
Side effects of green tea?
Definition
insomnia
Term
Vinca alkaloid, velban, acts by interfering with?
Definition
cell division production in the S phase
Term
The action of anti-neplastic drugs is to slow what?
Definition
the spread of cancer to other sites
Term
Alkylating drug + amioglycoside =
Definition
nephrotoxicity and ototoxicity
Term
plant alkaloids + warfarin =
Definition
increased risk prolonged bleeding
Term
Plank alkaloids work at the amin acid level of?
Definition
cell metabolism
Term
Normal cells reamin unaffected by anti-neoplasm drugs. T or F
Definition
false
Term
What is alopecia?
Definition
hair loose
Term
Cell cycle drugs attack a cell during?
Definition
the phases of cell division
Term
Myelo supression is?
Definition
anti-neoplastics interfere with the bone marrow's ability to make new cells
Term
Anemia occurs with?
Definition
a decreased production of RBC in the bone marrow
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