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Test 2
Chapters 5-7
97
Biology
Undergraduate 1
02/26/2012

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Term
Carbohydrates
Definition
most abundant of all the macromolecules
Term
Important in Cellular Functions of Carbohydrates
Definition
structure, energy, energy storage, cell identification
Term
Carbohydrate Components
Definition
-consists of C, H, O in a 1:2:1 ratio
-contains hydroxyl, carbonyl groups
-many dissolve easily or retain water
Term
Carb Types
Definition
-Monosaccharides
-Disaccharides
-Polysaccharides
Term
Monosaccharides
Definition
-simple sugars or monomers
-hexose (6C), pentose (5C), triose (3C)
-glucose, ribose, galactose
-used as fuel for cellular work
-shift from linear to ring forms in solution
Term
Disaccharides
Definition
-polymerization
-two monosaccharides linked together by oxygen bridge
-covalent bond in oxygen bridge (glycosidic linkage)
-sweet taste based on molecular shape
-sugars and non sugars
Term
140 lbs/year
Definition
number of lbs of sugar the average american intakes in 1 year (most in high fructose corn syrup)
Term
Polysaccharides
Definition
-long chains of glucose monomers
-chains branched are unbranched
Term
Energy Storage (Carbohydrates)
Definition
-storage polysaccharides
-glycogen (animal)
-starch (plant)
-energy comes from C-H or C-C bonds
-funnels energy into ATP synthesis
Term
Structure (Carbohydrates)
Definition
-structural polysaccharides
-cellulose (most abundant organic compound on earth) (no digestible fiber) (plant cell walls, wood)
-Chitin (glucose monomers with nitrogen) (exoskeleton, fungal cell walls)
-Peptidoglycan (glucose monomer with nitrogen and short peptide) (bacterial cell walls)
Term
Cell Identity (Carbohydrates)
Definition
-glycoproteins (allows cell to cell recognition)
Term
Lipids
Definition
-not a true polymer
-class of nonpolar hydrophobic compounds
-many contain fatty acids except sterols and derivatives
Term
Nonpolar Hydrophobic Compounds
Definition
-water is repelled
-composed of mostly C and H
Term
Sterols/Derivatives
Definition
types of lipids with no fatty acids
Term
Fatty Acids
Definition
-long hydrocarbon chain with carboxyl end
-unsaturated
-saturated
Term
Saturated
Definition
-no double bonds
-solid at room temperature
Term
Unsaturated
Definition
-one or more double bonds
-liquid at room temperature (oils)
Term
Types of Lipids
Definition
-fats
-hydrogenated oils
-waxes
-steroids
-phospholipids
Term
Ester Linkage
Definition
-3 fatty acids linked to a glycerol molecule
-commonly called triglycerides
-twice the energy of complex carbs
Term
Hydrogenated Oils
Definition
transfat
Term
Fat Functions
Definition
-insulation
-padding
-energy
-hormones
-vitamin transport/production
-structure for cell membrane
-70% of brain is fat
Term
Waxes
Definition
-long fatty acid chain linked to an alcohol
-repels water
-important in water proofing (feathers, fur)
Term
Steroids
Definition
-4 fused carbon rings with variable side and functional groups
-cholesterol is main type
Term
Cholesterol Functions
Definition
-plasma membrane component
-precursors to hormones and vitamin D formation
Term
Phospholipids
Definition
-major component of cell membrane
-composed of glycerol backbone, 2 FA tails, and hydrophilic phosphate head
Term
Phospholipid Functions
Definition
-acts as barrier
-amphipathic molecule
Term
Chemical Evolution
Definition
-phospholipids formed membrane around RNA
-created a microenvironment
-chemical reactions more efficient
-control of substance flow between environments
Term
Membrane Function
Definition
-controls activity at cells periphery
-selectively permeable
-controls flux of molecules and ions
-intercepts cell signals
Term
Membrane Structure
Definition
-fluid mosaic model
-phospholipid bilayer
Term
Phospholipid Bilayer
Definition
-main structural component of plasma membrane
-forms stable bilayer
-exhibits selective permeability
-non polar and small polar (oxygen, carbon dioxide) let inside
Term
Selective Permeability
Definition
-lets in small non polar and small uncharged polar
-does not let in large uncharged polar or ions
Term
Permeability Decreases With...
Definition
-longer FA tails
-saturated FA tails
Term
Fluidity of Phospholipid Bilayer
Definition
-free lateral movement
-consistency of vegetable oil
-increased by cholesterol and unsaturated FA's
-affected by temperature
Term
Integral Proteins in Mosaic
Definition
-cell recognition
-enzymes
-form cell junctions
-transport proteins (lets ions/electrolytes in)
Term
Passive Transport
Definition
-does not require energy
-across bilayer or transport proteins
-diffusion
-osmosis
Term
Active Transport
Definition
-requires energy and transport protein
Term
Diffusion
Definition
-high to low concentration
-down concentration gradients to equilibrium
-occurs with non polar and small polar molecules
Term
Osmosis
Definition
-passive transport of water
-moves down concentration gradient
-more free water moves to less free water
-directional flow is based on solute differences
Term
Osmotic Flow is Based On....
Definition
Tonicity
Term
Tonicity
Definition
-relative solute concentration of two fluids
-hypotonic
-hypertonic
-isotonic
Term
Hypotonic
Definition
-turgid
-fewer solutes
-H20 IN
Term
Hypertonic
Definition
-plasmolyze
-more solutes
-H20 OUT
Term
Isotonic
Definition
-flaccid
-same amount of solute
-H20 IN and OUT
Term
Channel Proteins
Definition
-allows large, charge or polar molecules
-water, sugars, amino acids, ions
Term
Aquaporin
Definition
-primary avenue for H20 transport
-exterior (hydrophobic)
-interior (hydrophilic)
Term
Electrochemical Gradient
Definition
charge and amount
Term
Gated Channels
Definition
-open with stimulus
-molecule binding
-charge change
Term
Carrier (transporter) Proteins
Definition
change shape allowing passage
Term
Active Transport (in depth)
Definition
-movement of solute agains electrochemical gradient
-requires ATP and protein pumps
-transport pump is activated by ATP
-binding of phosphate changes protein shape and affinity for solute
Term
Bulk Transport
Definition
-across permeable membrane
-exocytosis
-endocytosis
Term
Exocytosis
Definition
-transport large molecule OUT OF CELL
-vesicles fuse with membrane
Term
Endocytosis
Definition
-transport large molecules INTO CELL
-phagocytosis
-pinocytosis
-receptor mediated endocytosis
Term
Phagocytosis
Definition
cellular eating
Term
Pinocytosis
Definition
cellular drinking
Term
Receptor Mediated Endocytosis
Definition
specific intake
Term
Light Microscope
Definition
-glass lenses/light source
-magnify 1000X
-general shape
-single cell movements/habits
Term
Electron Microscope
Definition
-tungsten filament and magnetic lenses
-SEM (scanning)
-TEM (transmission)
Term
SEM
Definition
-scans surfaces
-50, 000X
Term
TEM
Definition
-internal structures
-250,000X
Term
All Cells Have
Definition
-plasma membrane
-cytoskeleton
-cytoplasm
-DNA
-ribosomes
Term
Plasma Membrane
Definition
controls contact with the environment
Term
Cytoskeleton
Definition
-structure
-division
-intracellular transport
Term
Cytoplasm
Definition
liquid (cytosol) and organelles outside nucleous
Term
DNA
Definition
genetic info within a region of the cell
Term
Ribosomes
Definition
site of protein synthesis
Term
Prokaryotes
Definition
domain bacteria/archaea (extremophiles)
Term
Prokaryotic Cell Structure
Definition
-Coccus (round)
-Bacillus (rod)
-Spirillim (spiral) (least common)
-single circular chromosome in nucleoid region
-plasmids
-specialized membranes
-flagella
-cell wall (peptidoglycan)
-capsule
-pili
Term
Plasmids
Definition
-small circular DNA molecules
-can transfer bacteria to bacteria
-antibiotic resistance
Term
Capsule
Definition
sticky film of monosaccharides
Term
Pili
Definition
sticky hairs that stick out like flagella
Term
Eukaryotic Cells
Definition
-larger than prokaryotic cells
-complexity in compartmentalization
-membrane bound organelles
-domain eukarya (plants, animals, protists, fungi)
Term
In Plant Cells But Not Animal Cells
Definition
-cell wall
-chloroplast
Term
Animals Cells But Not Plant Cells
Definition
centrioles
Term
Nucleus
Definition
-usually largest organelle except for in plants and fungi
-copying and dividing
-response to cell stimulus
Term
Structure of Nuclear Envelope
Definition
-complex double membrane
-lined by a nuclear lamina (fibrous proteins)
-perforated by nuclear pore complexes
Term
Function of Nuclear Envelope
Definition
-perforated pore complexes allow:
-trafficking of molecules
-trafficking molecules must have nuclear localization signal (NLS)
Term
Components of Nucleus
Definition
-chromatin
-nucleolus
-ribosomes
Term
Chromatin
Definition
long fibers of DNA and associated proteins
Term
Nucleolus
Definition
-rRNA is manufactured here
-ribosomal subunits are built
Term
Ribosomes
Definition
-consist of rRNA and proteins
-free floating or bound
-build proteins
Term
Endomembrane System
Definition
-membrane organelles working together
-manufacture, distribute, ship, store cellular products (proteins lipids)
-er, golgi, lysosomes, vesicles
Term
Endomembrane Function
Definition
-make cell products
-used by cell directly
-or follow the secretory pathway
-determined by pulse-chase experiment
Term
Endoplasmic Reticulum
Definition
-usually continues with nuclear envelope
-extensive
-main manufacturer of molecules
-smooth and rough
Term
Smooth ER
Definition
-series of interconnected tubules
-diversity of enzymes embedded in membranes
-assemble lipids (fatty acids, phospholipids, steroids) (hormones: gonads)
-in liver, inactivates wastes and drugs
-attaches -OH
-stores calcium ions (required for muscle contraction)
Term
Rough ER
Definition
-flattened sacs studded with ribosomes
-surface ribosomes produce proteins
-make membrane and secretory proteins
1. proteins enter rough er lumen and are modified (glycosylation)
2. polypeptide has signal sequence for binding (recognized by SRP)
3. cells specialized in secreting proteins have lots of rough er
Term
Golgi Apparatus
Definition
-stacks of membranous stacks (cisternae)
-finish, sort, ship proteins and lipids that arrive from er
-add/remove sugars, phosphates, or split proteins
-manufacture cell wall products
-cell products for secretion leave by exocytosis
Term
Apoptosis
Definition
-controlled killing of cells
-lysosomal derived cell death
-ducks (no activity)
-chicken (some activity)
-syndactly (lack of apoptosis can result in fused digits)
Term
Abnormal Lysosome Can Cause...
Definition
-fatal diseases
-lysosomal storage is hereditary
-Pompe's disease
-Tay-Sach's
Term
Pompe's Disease
Definition
glycogen breakdown
Term
Tay-Sach's Disease
Definition
lipid breakdown
Term
Vacuoles
Definition
-plants and fungi
-50-90% of cell volume
-general maintenance of the cell
-lysosomal storage functions
-stores amino acids, sugars, wastes, pigments
Term
Peroxisomes
Definition
-oxidize molecules (remove electrons)
-forms hydrogen peroxide
-detoxing the liver
-breaks down fat
-glyoxisomes (plants)
Term
Cytoskeleton
Definition
-helps organize cell structure ad activities
-made up of a network of protein fibers: 3 types
-microfilaments
-intermediate filaments
-microtubules
Term
Microfilitiments
Definition
-most slender
-actin (assemble/disassemble very rapidly)
-work with myosin motor proteins (stimulated by ATP)
Term
Intermediate Filaments
Definition
-medium sized and most permanent
-fibrous proteins (keratin)
-reinforces the cell (nucleus)
-anchors nucleus
-persist after cell death
Term
Microtubules
Definition
-hollow tubes of tubulin dimmers
-dynamic assembly/disassembly
-originate from microtubule organizing center (MTOC) (in animals, centrosome)
Term
Microtubule Functions
Definition
-involved in cell shape
-chromosome movement
-vesicle/organelle movement
-work with kinesin motor proteins
-move entire cell
-cilia and flagella
-structure is a 9 + 2 arrangement
-movement occurs by dynein arms (motors)
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